Clinical trials: Mental Health (Depression)
Diabetes, Hypertension
Pharmacy Interventions to Improve Chronic Disease Medication Refill
Compare the effectiveness of 3 strategies by pharmacists to decrease the time to refill of prescriptions for common chronic diseases (diabetes, hypertension, hyperlipidemia, heart failure, depression, psychoses).
- Conditions
- Diabetes, Hypertension, Hyperlipidemia, Heart Diseases
- Trial name
- NCT00469365
- Testing
- pharmacist contact with the patient via telephone, Pharmacist contact with the patient's physician via fax, Usual care
- Where
- United States
- Volunteers
- 3,048 people
- Sponsor
- Medical University of South Carolina
Depression
E-mental Health Support for Rural Areas
In the treatment of depression, primary care team play an important role, but they are most effective when inserted into a collaborative model of disease management.
- Trial name
- NCT02200367
- Testing
- e-mental health collaborative programme, Usual Care
- Volunteers
- 254 people
- Sponsor
- University of Chile
Chronic Pain, Depression
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depression.
- Trial name
- NCT07118722
- Testing
- Quiet Focus, Health Enhancement Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Depression, Quality of Life
Impact of Breathing Exercises and Meditation on Quality of Life in Dry Eye Disease Patients: A Pilot Study
People staring at computer screens for long hours, blinking less frequently, or having long-term contact lens wear are prone to dry eye disease (DED).
- Conditions
- Depression, Quality of Life, Dry Eye, Anxiety
- Trial name
- NCT03345381
- Testing
- SKY + ASTM + usual care, Usual care
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Major Depression, Generalized Anxiety Disorder (GAD)
Online Writing Intervention for Major Depressive Disorder
The goal of this trial is to examine the feasibility of administering an online writing intervention to patients diagnosed with Major Depressive Disorder, and whether this intervention impacts symptoms of depression.
- Trial name
- NCT06699719
- Testing
- Expressive writing
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Centre for Addiction and Mental Health
Risk Assessment, Resilience, Psychological
Resilience in Adolescent Development
RAD is a 10-year natural history, longitudinal, prospective assessment study of a cohort of 2,500 participants (ages 10-24 years) that will help uncover the socio-demographic, lifestyle, clinical, psychological, and…
- Conditions
- Risk Assessment, Resilience, Psychological, Depression, Mood Disorders
- Trial name
- RAD (NCT03458936)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
COPD, Depression
The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity
Chronic Obstructive Pulmonary Disease (COPD) is prevalent and debilitating chronic disease in Veterans. COPD is highly co-morbid with depression and anxiety conferring greater morbidity and mortality risk.
- Conditions
- COPD, Depression, Anxiety
- Trial name
- NCT04953806
- Testing
- Step-CBT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VA Office of Research and Development
Primary Dysmenorrhea (PD)
Pelvic Floor and Diaphragmatic Breathing Exercises for Primary Dysmenorrhea
This study investigates whether combining pelvic floor muscle exercises with diaphragmatic breathing exercises can reduce menstrual pain in women with primary dysmenorrhea.
- Trial name
- PFDD (NCT07263516)
- Testing
- Pelvic Floor + Breathing Exercises, Diaphragmatic Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Gelisim University
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stress, Anxiety
European platforM to PromOte Wellbeing and HEalth in the Workplace (EMPOWER)
EMPOWER is a multidisciplinary research and innovation effort aiming to developing, implementing, evaluating and disseminating the effectiveness and cost-effectiveness of a modular eHealth intervention platform to promote health…
- Conditions
- Stress, Anxiety, Depression, Insomnia
- Trial name
- EMPOWER (NCT04907604)
- Testing
- A multi-modal and integrative e-health platform aimed at promoting health and reducing the negative impact of mental problems in the workplace
- Volunteers
- 729 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Major Depressive Disorder (MDD, Anxiety Disorder, Generalized
Serotonin Variants & Gut Microbiota in Mental Health
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway (including serotonergic system, methylation cycle, intestinal barrier integrity, and inflammatory response…
- Conditions
- Major Depressive Disorder (MDD, Anxiety Disorder, Generalized, Stress Disorders, Post-Traumatic, Panic Disorder
- Trial name
- NCT07634458
- Testing
- SNP Genotyping and Gut Metagenomics
- Volunteers
- 30 people
- Sponsor
- Neurobiologix
Premenstrual Dysphoric Disorder, PMDD
The SPARK-PMDD Study
Scientists have found that the immune system, the body's system dedicated to fighting infections, can be in a state of "hyperactivity" (i.e., more active than you would normally expect) in some people with depression and…
- Conditions
- Premenstrual Dysphoric Disorder, PMDD, Premenstrual Dysphoric Disorder ( PMDD), Premenstrual Dysphoric Disorder (PMDD)
- Trial name
- SPARK-PMDD (NCT07771426)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King's College London
Peri-implantitis, Peri-implant Mucositis
Peri-Implant Sulcus Fluid Stress Markers in Health and Disease
This study examines the association between psychosocial stress and peri-implant diseases. Peri-implant diseases are inflammatory conditions affecting the tissues around dental implants and may contribute to implant failure.
- Conditions
- Peri-implantitis, Peri-implant Mucositis, Peri-Implant Health
- Trial name
- NCT07353515
- Testing
- Psychological Assessment, Peri-implant Sulcular Fluid Biomarker Analysis, Peri-implant Clinical Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Inonu University
Mental Disorder, Depressive Disorder
Reducing Stigma Among Healthcare Providers (RESHAPE-cRCT)
A growing number of trials have demonstrated treatment effectiveness for mental illness by non-specialist providers, such as primary care providers, in low-resource settings.
- Conditions
- Mental Disorder, Depressive Disorder, Anxiety Disorder, Alcohol Use Disorder
- Trial name
- RESHAPE-cRCT (NCT04282915)
- Testing
- Reducing Stigma among Healthcare Providers (RESHAPE), mental health Gap Action Programme
- Where
- Nepal
- Volunteers
- 8,705 people, healthy volunteers welcome
- Sponsor
- George Washington University
Pediatric Obesity, Pediatric Overweight
BasketballRx: Game Changing Health
The goal of this study is to learn if BasketballRx, a basketball and health program, works well for children and teens who are overweight or have obesity.
- Conditions
- Pediatric Obesity, Pediatric Overweight, Anxiety, Depression Disorders
- Trial name
- NCT07778433
- Testing
- BasketballRx
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Perinatal Depression, Perinatal Anxiety
Feasibility and Implementation of Early Referral in Perinatal Mental Health
This study is part of the e-Perinatal project and is embedded within the main cluster randomized trial. The primary aim is to evaluate the feasibility, acceptability, and preliminary effectiveness of an early diagnosis detection…
- Trial name
- e-Perinatal-Re (NCT07609550)
- Testing
- The e-Perinatal intervention is a personalized mobile health (mHealth) program, Standard routine maternal care
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Depression, Anxiety
Development and Evaluation of a CBT-based Transdiagnostic Transcultural Web App for Mental Health Problems
This study aims to (1) develop a CBT-based transcultural, transdiagnostic interactive web app and (2) assess the feasibility, acceptability, and preliminary efficacy of this intervention.
- Trial name
- WCBT (NCT06158763)
- Testing
- Web-based CBT guided self-help Interventions
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Major Depressive Disorder, Mood Disorders
Clinical Validation of Samsung Smartwatch
Objective: Wearable technology holds promising potential for mental health monitoring and detection. Samsung has developed an algorithm that they believe can detect signs of depression and anxiety in smartwatch users.
- Conditions
- Major Depressive Disorder, Mood Disorders, Mental Health Issue
- Trial name
- NCT05767593
- Testing
- Wearing Samsung smartwatch and filling out daily surveys
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress, Stress, Psychological
The Effect of SKY Breath Meditation on Health and Well-being
The goal of this pilot SKY (Sudarshan Kriya Yoga) Breath Meditation study is to establish feasibility and acceptability of the intervention; and investigate preliminary effectiveness of the intervention at the DNA methylation…
- Conditions
- Stress, Stress, Psychological, Stress, Physiological, Anxiety
- Trial name
- NCT05523414
- Testing
- SKY
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post Traumatic Stress Disorder
Childbirth-related Post-traumatic Stress Disorder in Switzerland: The Swiss Cohort on Traumatic Childbirth and Health
The goal of this observational study is to investigate the prevalence of Childbirth post-traumatic stress disorder (CB-PTSD) and Childbirth post-traumatic stress symptom (CB-PTSS) in Switzerland, and to analyze the psychological…
- Trial name
- SwiTCH (NCT05865704)
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
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