Clinical trials: Mental Health (Depression)
Perinatal Depression, Resilience
Development and Evaluation of SM-ART Intervention (SM-ART)
The approach of this intended research is to help pregnant women practice constructive coping and proactive skills that focus on positive adaptation for safe motherhood through our developed intervention.
- Conditions
- Perinatal Depression, Resilience, Anxiety, Marital Conflict
- Trial name
- SM-ART (NCT04694261)
- Testing
- SM-ART
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Critical Limb Threatening Ischaemia, Depression Disorder
Symptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI
Mental health disorders are common in older people and are often unrecognised. Those living with mental health disorders who are being considered for vascular surgery have worse post operative outcomes, including longer length of…
- Conditions
- Critical Limb Threatening Ischaemia, Depression Disorder, Anxiety
- Trial name
- NCT07529886
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Exercise
Effects of HIIT and MICT Training on Cardiorespiratory Fitness, Testosterone/Cortisol Ratio, and Mental Health in Young Adults
This study will use a randomized, double-blind clinical trial to evaluate the effects of eight-week HIIT and MICT exercise programs on cardiorespiratory fitness, the testosterone/cortisol ratio, and mental health in 68 healthy…
- Trial name
- NCT07397702
- Testing
- High-intensity interval training, Moderate-intensity continuous training
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Chronic Pain, Depression
Digital Tools for Coping With Chronic Pain
Chronic pain is becoming increasingly more prevalent worldwide. High rates of co-morbid psychological distress are also commonly found among individuals living with chronic pain.
- Conditions
- Chronic Pain, Depression, Anxiety, Opioid Use
- Trial name
- NCT03234439
- Testing
- myStrength
- Where
- 12 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- MyStrength, Inc.
Depression
Testing e-Mental Health in Lebanon
The study objective is to test a guided e-mental health intervention called Step-by-Step for people living in Lebanon. Step-by-Step is a self-help programme delivered through an app or website and aims to treat symptoms of…
- Trial name
- NCT03720769
- Testing
- Step-by-Step, Enhanced care as usual
- Where
- Lebanon
- Volunteers
- 1,248 people
- Sponsor
- VU University of Amsterdam
Chronic Pain, Depression, Anxiety
Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
The purpose of this research study is to refine customized in-app notifications in order to optimize users' experience with a mobile app called Wysa for Chronic Pain.
- Trial name
- NCT06978166
- Testing
- Just-In-Time Adaptive Interventions (JITAIs), Wysa for Chronic Pain
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Washington University School of Medicine
Depression, Anxiety
Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their…
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder
- Trial name
- NCT06324383
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depressive Disorder, Recurrent, in Remission, Major Depressive Disorder, Recurrent, Mild
Mindfulness-Based Cognitive Therapy (MBCT) for the Prevention of Depression Relapse or Recurrence Using Videoconference
Objectives: To evaluate the clinical- and cost-effectiveness of two delivery formats of mindfulness-based cognitive therapy (MBCT) - (i) MBCT delivered through eight videoconference group sessions (group MBCT), and (ii) MBCT…
- Conditions
- Major Depressive Disorder, Recurrent, in Remission, Major Depressive Disorder, Recurrent, Mild, Major Depressive Disorder, Recurrent, Moderate
- Trial name
- BECOME (NCT06832605)
- Testing
- Group Mindfulness-Based Cognitive Therapy, Mindfulness-Based Cognitive Therapy Self-Help, Treatment as Usual (TAU)
- Where
- 5 sites in Spain
- Volunteers
- 342 people
- Sponsor
- Fundació Sant Joan de Déu
Distress, PTSD
Scaling-up Psychological Interventions With Syrian Refugees in Switzerland (STRENGTHS_CH): RCT
The current refugee crisis across the Middle East and Europe has large effects on individual refugees' psychological well-being, as well as on the healthcare systems of countries hosting refugees.
- Conditions
- Distress, PTSD, Anxiety, Depression
- Trial name
- NCT04574466
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Depression, Anxiety
Testing a Digital Health Intervention App for Depression and Anxiety
Although mobile applications ("apps") for mental health are popular and widely available, little is known about how well they actually help people with common mental health symptoms of depression, anxiety, and stress.
- Trial name
- NCT05373329
- Testing
- Sanvello (app)
- Where
- United States
- Volunteers
- 4,607 people
- Sponsor
- University of Nevada, Las Vegas
ADHD, Conduct Disorder
Preventing Health Disparities in Hispanic Youth
This study seeks to investigate the efficacy and mechanisms of a highly promising "Culturally Informed Family Therapy for Adolescents" in preventing the emergence of two important health disparities in Hispanic youth, namely drug…
- Conditions
- ADHD, Conduct Disorder, Depression, Family Dysfunction
- Trial name
- CIFFTA-P (NCT02318745)
- Testing
- Culturally Informed Family Treatment for Adolescents, Individual Treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Miami
Doula Support, Postpartum
The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.
The primary objective of this research is to conduct a randomized clinical trial to examine the impact of nurse-coordinated, doula-delivered postpartum support (intervention arm) on postpartum health care utilization, health…
- Conditions
- Doula Support, Postpartum, Postpartum Depression (PPD), Postpartum Anemia
- Trial name
- NEST (NCT07787845)
- Testing
- Doula-delivered, Nurse-coordinated postpartum support
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of South Carolina
Periodontitis, Depression
Impact of Periodontal Therapy on Mental Health Parameters
Objectives: Primary: To determine the efficacy of periodontal treatment on mental health outcomes in patients with major depression and periodontitis.
- Trial name
- LeakBrainRCT (NCT06036472)
- Testing
- Standard periodontal therapy (steps 1 & 2), supragingival debridement with anesthesia (step 1)
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
COVID-19
Public Health Consequences of Covid-19
Aim of this observational study is to improve our understanding of the impact of Covid-19 on health. By an online questionnaire at least 60.000 people are invited by email to participate.
- Trial name
- NCT05128695
- Testing
- there is no intervention; the study is observational
- Where
- Netherlands
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Public Health Service South Limburg
Posttraumatic Stress Disorder, Cancer
PTSD Mobile App for Cancer Survivors
The purpose of this study is to use a stepped-care approach in treating symptoms of posttraumatic stress disorder (PTSD). The information learned by doing this study may help us to develop some target treatments for PTSD symptoms…
- Trial name
- NCT04058795
- Testing
- Cancer Distress Coach (CaDC) App, CaDC + mCoaching, mCBT
- Where
- 3 sites in United States
- Volunteers
- 524 people
- Sponsor
- Duke University
Perinatal Mental Health, Antenatal Depression
Enjoy Your Bump : Online Cognitive Behavioural Therapy in Pregnancy
A feasibility study evaluating how acceptable women experiencing low mood or anxiety during their pregnancy find an online Cognitive Behavioural Therapy course called 'Enjoy Your Bump'.
- Conditions
- Perinatal Mental Health, Antenatal Depression, Antenatal Anxiety
- Trial name
- NCT03373734
- Testing
- Enjoy Your Bump
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Burnout, Professional, Stress, Psychological
Foundational Programs to Combat Clinician Stress
This is a prospective, randomized, controlled clinical trial in which clinicians from University of Pennsylvania Health Systems (UPHS) including Penn Medicine- Lancaster General Health (LGH) and Massachusetts General Hospital…
- Conditions
- Burnout, Professional, Stress, Psychological, Stress, Physiological, Psychological Well-Being
- Trial name
- FACCTS (NCT07220421)
- Testing
- Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation, Health Education Program (HEP)
- Where
- 6 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06570993)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Depression, Schizophrenia
Norwegian Adult Mental Health Registry
"The Norwegian Adult Mental Health Registry" (NAMHR) is a medical quality register collecting and systematizing data on patients and their treatment in specialist mental health care for adults in Norway.
- Conditions
- Depression, Schizophrenia, Bipolar Disorder, Eating Disorders
- Trial name
- NAMHR (NCT06115200)
- Volunteers
- 150,000 people
- Sponsor
- Helse Stavanger HF
Mental Illness, Depression
Identifying Parents in Child Welfare Services Who Need Mental Health Support: Depression and Anxiety Symptoms
The main aim of this study is to examine the occurrence of mental health symptoms among parents referred to the Swedish child welfare services for child maltreatment and other family related risks.
- Conditions
- Mental Illness, Depression, Anxiety
- Trial name
- NCT06572865
- Testing
- Screening for depression and anxiety
- Where
- Sweden
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
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