Clinical trials: Mental Health (Depression)
Pre-Eclampsia, Depression
Preeclampsia Research on Vitamin D, Inflammation, & Depression
This study is designed to comprehensively investigate the anti-inflammatory role of vitamin D in reproductive aged women, and its association with preeclampsia and depression.
- Conditions
- Pre-Eclampsia, Depression, Inflammation, Vitamin D Deficiency
- Trial name
- PROVIDE (NCT03018132)
- Testing
- mental health screening, education and referral program
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Depression, OCD
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
The study involves multiple retrospective analyses to understand the utilization of mental health treatments provided at Greenbrook and their effectiveness
- Conditions
- Depression, OCD, Anxiety Depression
- Trial name
- NCT06997549
- Testing
- Patients treated with NeuroStar TMS, Patients treated with Esketamine
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Neuronetics
Depressive Symptoms, Anxiety
Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET
The investigators are evaluating the acceptability and effectiveness of brief online wellness modules. Participants will be randomly assigned to the intervention condition, an active control condition, or a wait-list control…
- Trial name
- COMET (NCT04586192)
- Testing
- Common Elements Toolbox- Adult version (COMET-A), Self-awareness Control
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
COPD, Quality of Life
Psychological Distress in Patients With COPD
Chronic obstructive pulmonary disease (COPD) can significantly impact a person's quality of life, not only physically but also mentally.
- Conditions
- COPD, Quality of Life, Mental Health, Psychological Distress
- Trial name
- NCT06395311
- Testing
- COPD psychological well-being assessment
- Where
- Romania
- Volunteers
- 98 people
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara
Breast Cancer, Laughter Therapy
The Effects of Laughter Yoga and Mindfulness-Based Stress Reduction (MBSR) Practices Applied to Women With Breast Cancer
Breast cancer is defined as the most common type of cancer that causes death among women (Siegel et al. 2019). It constitutes 24% of cancers and 15% of cancer-related deaths in women (T.R. Ministry of Health 2020).
- Conditions
- Breast Cancer, Laughter Therapy, Mindfulness Therapy, Life Quality
- Trial name
- NCT06116812
- Testing
- the laughter yoga group, the mindfulness based stress reduction group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Kafkas University
Mental Health Issue
Improving the Mental Health of Home Health Aides
The goal of this study is to improve the mental health of home health aides, a workforce that provides care for adults at home but whose own health has been historically poor.
- Trial name
- MINDSET (NCT06071221)
- Testing
- Living Healthy educational program + peer coaching, Living Healthy educational program
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depression, Anxiety Disorders
The PredictPlusPrevent Study
Objective: To design, develop, and evaluate a personalized intervention for the universal prevention of depression and anxiety in the general population based on risk algorithms, ICTs, and decision support systems (DSS).
- Trial name
- NCT06351800
- Testing
- Predictplusprevent intervention, Psychoeducational intervention
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- The Mediterranean Institute for the Advance of Biotechnology and Health Research
Adolescent - Emotional Problem, Agent
A Virtual Peer Agent for Counseling Adolescents With Stressful Life Events
This study aims to develop and evaluate a virtual companion agent for providing psychological support to adolescents who have recently experienced stressful life events. This is a single-arm, pre-post pilot trial.
- Conditions
- Adolescent - Emotional Problem, Agent, Psychological, Conversational
- Trial name
- NCT07305064
- Testing
- Virtual Peer Agent Counseling
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Sun Yat-sen University
Premature Birth, Low Birth Weight
Pilot Trial of CenteringPregnancy With Mindfulness Skills
In the U.S., rates of preterm birth and low birth weight have increased over the past 30 years. Poor birth outcomes are especially high among racial/ethnic minority populations.
- Conditions
- Premature Birth, Low Birth Weight, Postpartum Depression
- Trial name
- NCT01646463
- Testing
- CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Youth Mental Health, Anxiety
Using Conversational AI to Teach Growth Mindset Skills to Youths in India
This study aims to test whether a brief digital intervention using conversational AI can improve mental health outcomes among school-aged youth (grades 6-8) in India, where most young people with mental health issues do not…
- Conditions
- Youth Mental Health, Anxiety, Depression
- Trial name
- NCT07316647
- Testing
- Growth mindset training using conversational AI
- Where
- India
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Harvard University
Mental Health
Trial Phase: Syndemic Adapted Medly Uganda
The purpose of this study is to evaluate the effectiveness of the Syndemic-Adapted Medly Uganda (SAMU) in improving mental health care among adults living with HIV and hypertension in Uganda.
- Trial name
- SAMU (NCT07525271)
- Testing
- Syndemic-Adapted Medly Uganda (SAMU)
- Where
- 3 sites in Uganda
- Volunteers
- 1,500 people
- Sponsor
- Yale University
Depression
Mental Health in Adults and Children- Frugal Innovations (MAC-FI): Adult Depression Component
This stepped wedge, randomized controlled trial will test the effectiveness of a Supported Self-Management intervention for depression among adults in Vietnam.
- Trial name
- MAC-FI (NCT03001063)
- Testing
- Supported Self-Management, Enhanced treatment as usual
- Where
- Vietnam
- Volunteers
- 376 people
- Sponsor
- Simon Fraser University
Nonsuicidal Self Injury, Suicidal Ideation
Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults
This is a feasibility trial of a digital mental health intervention aimed at young adults (ages 18-25) with nonsuicidal self-injury and who are not currently engaged in mental health treatment.
- Conditions
- Nonsuicidal Self Injury, Suicidal Ideation, Depression, Anxiety
- Trial name
- NCT05325944
- Testing
- Self-guided digital intervention for NSSI, Digital intervention for NSSI with coaching, Active control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Depression
Improving Mood in Veterans in Primary Care
The purpose of the Improving Mood in Veterans in Primary Care (IIR 14-047) is to evaluate a brief educational individual workshop that is meant to help Veterans better understand feelings of sadness and ways to improve their…
- Trial name
- NCT02276807
- Testing
- Brief Behavioral Activation, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development
Psychological Distress, Anxiety
The Short-term Effects of PRISMA on Mental Health
Given the high prevalence of mental health issues, such as anxiety and depression, in pretrial detainees, the Swiss Federal Justice Department (SFJD) approved a model trial ("Modellversuch Untersuchungshaft", MV).
- Conditions
- Psychological Distress, Anxiety, Depression, Suicidal Ideation
- Trial name
- PRISMA (NCT06197711)
- Testing
- PRISMA
- Where
- Switzerland
- Volunteers
- 1,480 people
- Sponsor
- University of Zurich
Perimenopause, Menopause
The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.
The aim of this clinical trial is to determine if resistance training and a newly developed plant-based nutritional supplement can improve the symptoms and musculoskeletal health of perimenopausal women.
- Trial name
- NCT07135232
- Testing
- Sarmentosin - L- theanine, Resistance Training
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Depressive Symptoms
EMA Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms
Youth depression is a matter of concern worldwide. It affects an important part of the young population around the world and its consequences both physically and mentally make this issue an important research field for…
- Trial name
- NCT04830527
- Testing
- EMA prompting for patients, PDF Reports for therapists
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Vania Martínez-Nahuel
Major Depression
Thyroid Medication and Antidepressants for Treating Major Depression
This study will evaluate the effectiveness of treatment with supplemental triiodothyronine (T3, Cytomel) and sertraline (Zoloft), a selective serotonin reuptake inhibitor (SSRI), in improving symptoms of major depressive disorder…
- Trial name
- NCT00208702
- Testing
- Triiodothyronine, Sertraline
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Emory University
Cigarette Smoking
Tailored Tobacco Quitline for Rural Veterans
The proposed work is designed to help increase access to tobacco cessation services among rural veterans and to develop more effective treatment services that better address comorbid issues commonly experienced by rural smokers.
- Trial name
- NCT01592695
- Testing
- Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
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