Clinical trials: Mental Health Disorders
Metabolic Syndrome, Obesity
Low-intensity Exercise in Metabolic Syndrome
People with metabolic syndrome (MetS) are characterized by a lower quality of life in terms of reduced vital activity, emotional state, and social functioning.
- Conditions
- Metabolic Syndrome, Obesity, Hypertension, Hyperlipidemias
- Trial name
- NCT04346836
- Testing
- Low-intensity, general-fitness exercises, Psychoeducation
- Where
- Poland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Dental Diseases, Schizophrenia
Oral Status of Patients Suffering From SCHIZophrenia Followed at Charles Perrens Hospital
The aim of the study is to describe the oral health status of patients suffering from schizophrenia and schizoaffective disorders in a psychiatric institute in France.
- Trial name
- BUCCOSCHIZ (NCT04191200)
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Oral Health
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or…
- Trial name
- NCT06969092
- Testing
- Oral Frailty
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Quality of Life (QOL), Mental Wellbeing
Arts for Wellness (AFW): Arts-Based Social Prescribing During Inpatient Rehabilitation for Older Adults in Singapore
This mixed-methods study examined whether Arts for Wellness (AFW), an artist-led arts programme introduced during inpatient rehabilitation, improves mental wellbeing among older adults in a Singapore community hospital, and…
- Conditions
- Quality of Life (QOL), Mental Wellbeing, Anxiety, Depression
- Trial name
- SPNAC (NCT07851467)
- Testing
- Arts for Wellness - Dance, Arts for Wellness - Literary arts
- Where
- Singapore
- Volunteers
- 288 people
- Sponsor
- SingHealth Community Hospitals
Tobacco Use Disorder
Financial Incentives for Smoking Cessation
The purpose of this study is to test the effectiveness of financial incentives for increasing long-term smoking cessation rates among employees at General Electric worksites throughout the United States.
- Trial name
- NCT00128375
- Testing
- Financial incentives
- Where
- United States
- Volunteers
- 878 people
- Sponsor
- University of Pennsylvania
Health-related Quality of Life, Emotional Well-being
Enhancing Health-related Quality of Life, Emotional Well-being and Reducing Anxiety: Integrated Psychoeducational Nursing Interventions in Patients Undergoing Modified Electroconvulsive Therapy
Background: Electroconvulsive Therapy (ECT) remains a highly effective intervention for severe psychiatric disorders yet concerns about cognitive and emotional side effects persist.
- Conditions
- Health-related Quality of Life, Emotional Well-being, Modified Electroconvulsive Therapy
- Trial name
- NCT07579819
- Testing
- - After baseline measurement, the 120 patients were randomly divided into two equal groups: Study (Intervention) group (n = 60): received the multidisciplinary psychiatric nursing intervention session, No intervention (observational study)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shereen
Mental Health Wellness 1, Depression
Addressing Mental Health of Cancer Patients and Caregivers Using a Mobile App Suite
A cancer diagnosis affects not only patients but also their caregivers. The purpose of this study is to test the feasibility of using a mobile app suite, IntelliCare, to improve the mental health of cancer patients and caregivers.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety
- Trial name
- NCT03488745
- Testing
- IntelliCare + Phone Coaching
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Autism, Trauma
A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults
The goal of this single-group clinical trial is to learn about the initial efficacy and feasibility of telehealth-delivered Written Exposure Therapy (WET) for autistic adults with traumatic stress symptoms.
- Conditions
- Autism, Trauma, Posttraumatic Stress Disorder, Posttraumatic Stress Symptom
- Trial name
- NCT05862467
- Testing
- Written Exposure Therapy (WET) via telehealth
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wyoming
Schizophrenia, Schizoaffective Disorder
Evaluation of mHealth for Serious Mental Illness
This study is a waitlist control trial evaluating the acceptability and preliminary efficacy of a smartphone application with people with mental illness.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Major Depressive Disorder, Bipolar Disorder
- Trial name
- NCT04068467
- Testing
- Smartphone App, Waitlist Control
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Washington
Pediatric Obesity, Binge-Eating Disorder
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and…
- Trial name
- NCT04701671
- Testing
- Observational (not including MRI scanning), Observational (including MRI scanning)
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcoholism
Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in Alcoholics
This is a randomized, placebo controlled trial of dietary zinc and S-adenosylmethionine (SAMe) in otherwise healthy alcoholic US Veterans.
- Trial name
- ExZACTO (NCT01899521)
- Testing
- Bronchoscopy, Zinc sulfate 220 mg once daily, S-adenosylmethionine 400 mg twice daily
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- VA Office of Research and Development
Motivational Interviews, Bipolar Disorder
Motivational Interviewing in Patients With Bipolar Disorder
Introduction: A poor therapeutic relationship, poor quality of life, impaired functioning, ineffective coping methods, and lack of motivation It is associated with poor adjustment (to symptoms, treatment, and environment) in…
- Trial name
- NCT05428241
- Testing
- Assigned Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Pamukkale University
Cognition, Affect (Mental Function)
PRECOG Pilot Project
This pilot study aims to investigate the chronic effects of a prebiotic blend on cognitive, affective and gut microbiome outcomes in healthy adults aged 60-75 years.
- Conditions
- Cognition, Affect (Mental Function), Gut Microbiome
- Trial name
- NCT06911957
- Testing
- Prebiotic blend
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading
Major Depressive Disorder
Mobile Screening for Major Depressive Disorder in Adults From an Ethnically and Socioeconomically Diverse Population.
Major depressive disorder (MDD) is a mental disorder leading to a variety of emotional and physical problems affecting almost 300 million people worldwide.
- Trial name
- MOOD (NCT05989412)
- Testing
- Patient health questionnaire-9 via the Your Research application
- Where
- Netherlands
- Volunteers
- 1,786 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Overweight and Obesity
Effect of a Group Intervention Program Based on Acceptance and Mindfulness on the Physical and Emotional Well-being of Overweight and Obese Individuals
The objective of the present study is to evaluate the effect of a 20-week group intervention program based on acceptance and mindfulness in emotional eating, weight loss, physiological parameters and the level of physical…
- Trial name
- Mind&Life (NCT03718728)
- Testing
- Mind&Life, Standard
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Mental Health Disorder
Arena Labs - Improving Clinician Well Being
To determine the efficacy of the asynchronous performance coaching platform, Arena Strive at changing measures of physiological resilience, professional fulfillment, burnout, and self-valuation in full time clinicians.
- Trial name
- NCT05653700
- Testing
- Arena Strive, Control Cohort
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cognitive Dysfunction
Immersive Nature-Based Wellbeing Program in Older Adults With Cognitive Impairment
This study aims to evaluate an immersive virtual reality program designed to support cognitive and emotional well-being in older adults with mild to moderate cognitive impairment.
- Trial name
- COGNITIO (NCT07802392)
- Testing
- Immersive virtual reality program
- Where
- Spain
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Depressive Symptoms, Major Depressive Disorder
Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology
The primary aim of this pilot study is to assess the feasibility, acceptability, and preliminary evidence of efficacy of a self-guided, cognitive behavioral therapy (CBT)-based mobile app intervention (SparkRx) for symptoms of…
- Conditions
- Depressive Symptoms, Major Depressive Disorder, Depression, Cardiology
- Trial name
- NCT05461599
- Testing
- SparkRx Mobile App
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Limbix Health, Inc.
Nicotine Dependence
Trial on the Effectiveness of Mindfulness Training for Smokers
The Mindfulness Training for Smokers study follows a randomized controlled design with 240 total participants. Both the study group and the control group will be enrolled in the Wisconsin Tobacco Quit Line and will receive four…
- Trial name
- MTS (NCT01093599)
- Testing
- Quit Line plus MTS, Quit Line Only
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Wisconsin, Madison
Substance Use Disorders, HIV
Implementing Technology-Assisted Drug Treatment and Relapse Prevention in Federally Qualified Health Centers (FQHCs)
Implementing a mobile-phone based system for drug use disorders in primary care settings.
- Trial name
- Seva (NCT01963234)
- Testing
- Seva
- Where
- 3 sites in United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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