Clinical trials: Mental Illness
Major Depression, Anxiety Disorders
Internet-Delivered Cognitive Behavior Therapy for Anxiety and Depression Amongst French Canadians
This study represents Phase II of a research program involving an international collaboration with Macquarie University (Sydney, Australia) to implement an Internet-based cognitive behavior therapy for the treatment of anxiety…
- Trial name
- NCT03043833
- Testing
- The Wellbeing Course
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Universite de Moncton
Opioid-induced Constipation
Long Term Safety of Naldemedine
The purpose of this study is to evaluate the long-term safety of naldemedine for the treatment of constipation due to opioid therapy.
- Trial name
- NCT01965652
- Testing
- Naldemedine
- Where
- 186 sites in United States, Australia and 14 more
- Volunteers
- 1,246 people
- Sponsor
- Shionogi
Bipolar Depression
Dopamine D3 Receptor Occupancy in Bipolar Depression
Bipolar disorder is a common condition that can cause significant disability and risk for suicide. Second generation antipsychotic medications can be used to treat depression in bipolar disorder, yet we do not know how they work.
- Trial name
- NCT05060549
- Testing
- Cariprazine
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Posttraumatic Stress Disorder, Family Members
Testing a Peer-led Trauma-focused Intervention for Significant Others of Those With BPD
This project involves developing and piloting a peer-led intervention focused on posttraumatic stress symptoms for the family members and significant others of people with borderline personality disorder.
- Conditions
- Posttraumatic Stress Disorder, Family Members, Spouses
- Trial name
- NCT06135090
- Testing
- Trauma Recovery Program (official title TBD)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- York University
Attention Deficit Hyperactivity Disorder (ADHD)
Cognitive-Motor Training With the DextEgg in Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) is frequently accompanied by deficits in executive functions and fine motor skills, which affect daily activities, academic performance, and health-related quality of life.
- Trial name
- ADHD DextEgg (NCT07913997)
- Testing
- Cognitive-motor DextEgg training, Motor-only DextEgg training
- Volunteers
- 50 people
- Sponsor
- Manuela Pastore-Wapp
Mental Disorder
AI-Assisted Rapid Warning for Mental Disorders Based on High-Resolution Fundus Imaging and High-Speed Eye-Tracking
This project aims to collect eye-tracking trajectories and fundus imaging data from individuals seeking mental health services. By utilizing artificial intelligence, combining dynamic (eye-tracking) and static (fundus) data, and…
- Trial name
- NCT06511713
- Testing
- routine clinical treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Mental Health Center
Normal Pressure Hydrocephalus
Flow MRI in Normal Pressure Hydrocephalus
Normal pressure hydrocephalus diagnosis based on quantitative study of cerebro-spinal fluid and blood flow by phase contrast magnetic resonance imaging.
- Trial name
- HydroFlux (NCT01909960)
- Testing
- Flow imaging
- Where
- 2 sites in France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Insomnia, Cancer
The Sleepio After Cancer Study
This study will recruit women over the age of 18 with a current or prior cancer diagnosis who have clinical insomnia. This study will examine the efficacy of digital cognitive behavioural therapy for insomnia (dCBT-I) compared to…
- Trial name
- SACS (NCT05816460)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia (dCBT-I), Sleep Hygiene Education (SHE)
- Where
- Ireland
- Volunteers
- 308 people
- Sponsor
- University College Dublin
Disordered Eating Behaviors, Disordered Eating
Can a Single-session Intervention Decrease Risk for Mental Health Symptoms in Young Adults? A Preliminary Investigation of Feasibility and Acceptability
This project has two primary aims: 1) to develop a single session intervention to understand different forms of self-evaluation with input from young adults, and 2) to examine whether a single session can improve the ways in…
- Trial name
- NCT07149324
- Testing
- Single Session for Overevaluation
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chloe White
Opioid-Related Disorders, Neuralgia
Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine Resection
Using combination of opioid analgesics and analgesics with different mechanism of action the investigators can decrease the consumption of opioid analgesics and their side effects.
- Trial name
- NCT02616523
- Testing
- Dexmedetomidine, Lidocaine, Fentanyl
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Social Anxiety Disorder
Efficacy of an Attention Guidance VR Intervention for Social Anxiety Disorder
Social anxiety disorder (SAD) is a prevalent mental health concern that impacts approximately 12% of the population. One mechanism thought to maintain SAD is avoidance of faces (i.e. avoidance of negative evaluative threat).
- Trial name
- NCT03683823
- Testing
- Attention guidance, Control intervention
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas at Austin
Attention Deficit Hyperactivity Disorder
An Open Label Phase I/II Study of the Safety and Dopamine Transporter Binding Properties of C-11 Altropane in Normal Human Subjects and in Subjects With ADHD
The primary objective of this study is to evaluate the Binding Potential in subjects with ADHD and adults without ADHD: the intent being to demonstrate that C-11 Altropane PET can be used to differentiate adults with ADHD from…
- Trial name
- NCT00302380
- Testing
- PET imaging using C-11 altropane as the ligand.
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer's Disease
Project ACT: Advancing Caregiving Techniques
The specific aims of this study are to: 1. Test the immediate effectiveness of the intervention to reduce caregiver upset with targeted disruptive behaviors (primary outcome).
- Trial name
- NCT00259480
- Testing
- Home Based Intervention
- Where
- United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
ADHD
Amiloride Hydrochloride as an Effective Treatment for ADHD
The investigators are proposing to test a medication derived from our prior studies of the gene SLC9A9. This one gene makes NHE proteins that control how we learn and remember items, which is impaired in ADHD and may cause an…
- Trial name
- NCT01733680
- Testing
- amiloride, Behavioral
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- State University of New York - Upstate Medical University
Sexual Dysfunction, Erectile Dysfunction
Botulinum Toxin for Erectile Dysfunction
To evaluate the safety and efficacy of intra-cavernosal Botulinum toxin injection as an alternative line of treatment in patients with erectile dysfunction - not responding to oral PDE5i - through cavernosal smooth muscle…
- Trial name
- NCT03102762
- Testing
- Botulinum Toxin Type A, Normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Alcohol Drinking, Alcohol Use Disorder
Contributing Factors of Solitary Drinking Among Adolescents and Young Adults
A convenience sample of 40 solitary drinkers aged between 10 and 24 will be invited to complete a structured questionnaire and a individual semi-structured interviews.
- Trial name
- NCT05337488
- Testing
- questionnaire with interview
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Alcohol Dependence
Effectiveness of Extended Telephone Monitoring
The purpose of this study is to determine the effectiveness of extended telephone monitoring for alcohol-dependent patients receiving intensive outpatient treatment.
- Trial name
- ETM (NCT00194103)
- Testing
- Telephone Monitoring and Feedback, Telephone Monitoring and Counseling
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Post-traumatic Stress Disorder
Diary for Severe Trauma
Treatment of severe trauma patients includes intensive cares. Both trauma and intensive care may lead to a post-traumatic stress disorder and then to a decreased quality of life.
- Trial name
- Qualitrau (NCT02305303)
- Testing
- Diary
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium
Clinical Evaluation Program of DeltaScan (Ward)
Rationale: Delirium, or acute brain failure, presents as an acute confusional state, and is associated with prolonged hospitalization, an increased risk of dementia, institutionalization and mortality, as well as increased costs.
- Trial name
- NCT03735927
- Where
- Netherlands
- Volunteers
- 3,907 people
- Sponsor
- UMC Utrecht
Nicotine Dependence
Nicotine Related Brain Activity: The Influence of Smoking History and Blood Nicotine Levels
In this study, we sought to explore brain activity in nicotine-dependent men in response to acute intravenous nicotine using pharmacological magnetic resonance imaging (phMRI).
- Trial name
- NCT01588561
- Testing
- Intravenous Nicotine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.