Clinical trials: Mental Illness
Cardiac Disease
Role of Cerebral Oximetry In Reducing Delirium After Complex Cardiac Surgery
Delirium after cardiac surgery is reported in a range of 3-47% of patients. Delirium is a serious complication that results in prolonged length of stay, increased health care costs and is associated with higher death rates.
- Trial name
- NCT01707446
- Testing
- Cerebral oximetry monitor (The INVOS® Cerebral/Somatic Oximeter), An alarm threshold at 75% of the baseline rSO2 value
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University Health Network, Toronto
Bipolar Disorder
Toi Même: a Mobile System for Measuring Bipolar Illness
Bipolar disorder is a severe psychiatric illness with chronic course and it is associated with high risk of relapse and hospitalisation, and many patients do not recover to their previous psychosocial functioning.
- Trial name
- NCT03508427
- Testing
- Daily self-monitoring
- Where
- 3 sites in France
- Volunteers
- 36 people
- Sponsor
- Institut Pasteur
Autism Spectrum Disorder
The Relationship Between Parents' Fatigue and Quality of Life
By comparing them to a healthy control group, this study aims to investigate the relationship between the participation of children with autism spectrum disorder (ASD) in home, school, and community environments and their…
- Trial name
- NCT05422261
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Alzheimer Disease, Mild Cognitive Impairment
Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia
This study is being performed to generate data regarding brain vibration /oscillation differences between individuals with dementia and normal controls.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Frontotemporal Lobar Degeneration, Memory Disorders
- Trial name
- NCT02333942
- Testing
- Nautilus NeuroWaveTM System
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Lung Cancer, Tobacco Use Disorder
Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients
RATIONALE: Continued smoking after a cancer diagnosis has important health consequences beyond the risks associated with smoking in the general population.
- Conditions
- Lung Cancer, Tobacco Use Disorder, Breast Cancer, Colorectal Cancer
- Trial name
- NCT01434342
- Testing
- Nicotine Replacement Patch
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Wake Forest University Health Sciences
Schizophrenia
Comparative Bioavailability of Risperidone
This is an open-label, one sequence study to evaluate the steady-state comparative bioavailability of 100 mg Risperidone ISM® injectable every 4 weeks compared to once daily 4 mg oral risperidone in subjects with schizophrenia…
- Trial name
- NCT03527186
- Testing
- Risperidone ISM® 100 mg
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- Rovi Pharmaceuticals Laboratories
Burnout, Anxiety
Art Therapy to Address Hospital Clinician Burnout
A structured group art therapy intervention, comprising six 60 - 90-minute weekly workshops.
- Conditions
- Burnout, Anxiety, Stress, Depression
- Trial name
- CHArt (NCT05728086)
- Testing
- Group art therapy
- Where
- United Kingdom
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Schizophrenia
The Establishment of the Early Intervention Program for Patients With Schizophrenia
Schizophrenia is a severe mental illness, which has a prodromal phase of 1-2 years prior to the onset of the illness. During the prodromal phase, patients might show maladaptation and/or poor social functioning.
- Trial name
- NCT00172770
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Memory Impairment, Amnesia
Sedation and Memory Consolidation
The study of plasticity processes, in particular, memory, is one of the fundamental directions in anesthesiology. To date, there are different views on the impact of sedation and anesthesia on memory.
- Conditions
- Memory Impairment, Amnesia, Recall, Recognition
- Trial name
- NCT05045170
- Testing
- Influence of propofol sedation on memory consolidation and 'working memory', Influence of dexmedetomidine sedation on memory consolidation and 'working memory', Influence of spinal anesthesia on memory consolidation and 'working memory'
- Where
- Russia
- Volunteers
- 81 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Obesity & Overweight, Eating Disorders
Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents
Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities.
- Conditions
- Obesity & Overweight, Eating Disorders, Body Image Disturbance, Gender Diverse Populations
- Trial name
- NCT07466069
- Testing
- TransForm Health Program
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Functional Movement Disorder, Functional Neurological Disorder
Tremor Retrainer Software Application for Functional Tremor
The purpose of this clinical trial is to learn about the Tremor Retrainer smartphone application and Simplified Functional Movement Disorder Rating Scale in patients with functional tremor.
- Conditions
- Functional Movement Disorder, Functional Neurological Disorder, Functional Neurological Symptom Disorder
- Trial name
- NCT06257069
- Testing
- Tremor Retrainer Smartphone Application
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Schizophrenia
Positron Emission Tomagraphy (PET) Study Following a Single Oral Dose of OPC-34712
Determine the degree of striatal D2 receptor occupancy induced by OPC-34712 at differenht dose levels in healthy volunteers.
- Trial name
- NCT00805454
- Testing
- OPC-34712
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Cannabis Use Disorders
Stress and Marijuana Cue-elicited Craving and Reactivity
The purpose of this study is to explore the interaction between stress and marijuana cues, in hopes that it may lead to the development of new treatments for marijuana dependence.
- Trial name
- NCT00613405
- Testing
- Stress + cue exposure, No stress + cue exposure
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Medical University of South Carolina
Postoperative Delirium
Dexmedetomidine vs Midazolam in Coronary Artery By-pass Surgery
The aim is to compare the incidence of postoperative delirium following coronary artery bypass grafting (CABG) between patients receiving dexmedetomidine and those receiving midazolam infusions.
- Trial name
- NCT07411794
- Testing
- Intravenous Dexmedetomidine infusion + Standard Anesthesia, intravenous midazolam infusion + Standard anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University
Major Depressive Disorder, Dysthymia Disorder
Oxytocin Add-on for Stable Depressed Patients
The objective of the study is to compare the efficacy of intranasal oxytocin versus intranasal placebo to improve depression symptoms in patients with Major Depressive Disorder (MDD) or Dysthymia Disorder.
- Trial name
- NCT01211756
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- David Feifel
Depression, Post-Traumatic Stress Disorder
Depression Screening in Primary Care: Using HIT for Patients With Limited English
This study assessed the potential of Health Information Technology (HIT) to improve the screening, diagnosis, and treatment of depression and post-traumatic stress among LEP Southeast Asians.
- Trial name
- NCT03191929
- Testing
- HIT Intervention, Minimal Intervention Control Arm
- Volunteers
- 410 people
- Sponsor
- Dara Sorkin
Postoperative, Delirium
Dexmedetomidine for the Treatment of Delirium After Heart Surgery
Primary hypothesis: Dexmedetomidine is equal or superior to haloperidol and placebo in the treatment of psychomotor confusion in patients who are recovering from heart surgery.
- Conditions
- Postoperative, Delirium, Psychomotor, Confusion
- Trial name
- DexinDelir (NCT01140529)
- Testing
- Dexmedetomidine, Haloperidol, Saline
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Thorax-Kärlkliniken
Psychosis, Schizophrenia and Other Psychotic Disorders
What is the Feasibility of Narrative Exposure Therapy (NET) for People Experiencing Psychosis?
The goal of this interventional study is to evaluate the feasibility of Narrative Exposure Therapy (NET) for people experiencing psychosis.
- Trial name
- NCT07237529
- Testing
- Narrative Exposure Therapy (NET)
- Volunteers
- 1 people
- Sponsor
- University of Nottingham
Speech, Autism Spectrum Disorder (ASD)
Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder
Recent studies indicate that children with ASD have a significantly higher risk of co-occurring speech sound disorders than typically developing children.
- Trial name
- NCT07472829
- Testing
- Approaches to ASD social intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Nursing, Hemodialysis Patient
THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES IN HEMODIALYSIS PATIENTS
The aim of this study is to determine the effect of Progressive Relaxation Exercise (PGE) applied according to the circadian rhythms of hemodialysis (HD) patients on symptom management, sleep quality, comfort and mental…
- Conditions
- Nursing, Hemodialysis Patient, Circadian Rhythm, Relaxation Exercise
- Trial name
- NCT07499297
- Testing
- Progressive Relaxation Exercises
- Volunteers
- 75 people
- Sponsor
- Karamanoğlu Mehmetbey University
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