Clinical trials: Mental Problems
Autistic Disorder, Constipation
Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress
The clinical manifestation of autism spectrum disorder (ASD) is complex, with medical and mental health disruptions that occur with the three core behavioral criteria used for diagnosis (social behavior, communication, restricted…
- Conditions
- Autistic Disorder, Constipation, Gastrointestinal Diseases
- Trial name
- NCT02442115
- Testing
- Treatment of Functional Constipation by
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Post-Traumatic Stress Disorder (PTSD)
Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
Leveraging veterans' intimate relationships during treatment for posttraumatic stress disorder (PTSD) has the potential to concurrently improve PTSD symptoms and relationship quality.
- Trial name
- CBCT-OT RCT (NCT06194851)
- Testing
- Oxytocin nasal spray, Saline nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Mild Cognitive Impairment
Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain
The investigators aim to conduct a fully powered randomized controlled trial to compare the efficacy of two symptom management programs for older adults with early cognitive decline (either self-reported or confirmed by testing)…
- Conditions
- Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
- Trial name
- NCT05373745
- Testing
- Active Brains 1, Active Brains 2
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Massachusetts General Hospital
Conduct Problems, Anxiety Symptoms
Testing the Effectiveness of Supportive Parents - Coping Kids
The aim of this clinical trial is to test the effectiveness of the parent training intervention Supportive Parents - Coping Kids (SPARCK) for prevention of childhood mental health problems.
- Conditions
- Conduct Problems, Anxiety Symptoms, Depressive Symptoms
- Trial name
- SPARCK (NCT05800522)
- Testing
- Behavioral parent or child directed intervention, Supportive Parents - Coping Kids
- Where
- Norway
- Volunteers
- 252 people
- Sponsor
- Norwegian Center for Child Behavioral Development
Sleep Problem, Bipolar Disorder
Better Sleep in Psychiatric Care - Bipolar
Cognitive Behavioral Therapy (CBT) is treatment of choice for insomnia. Many patients in psychiatric care have sleep problems including insomnia, but are rarely given the choice to participate in CBT to improve their sleep.
- Trial name
- BSIP-Bipolar (NCT04130529)
- Testing
- Adjusted group CBT-i for Bipolar disorder, Sleep lectures
- Where
- 2 sites in Sweden
- Volunteers
- 87 people
- Sponsor
- Karolinska Institutet
Hepatic Encephalopathy, Covert Hepatic Encephalopathy
Affect of Melatonin on Sleep and Cognition in Cirrhosis
The goal of this clinical trial is to learn the affect of melatonin on sleep, cognitive function, and quality of life (QoL) in patients with cirrhosis and a complication called hepatic encephalopathy (HE).
- Conditions
- Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and Insomnia
- Trial name
- SNORE-HE (NCT07046429)
- Testing
- Melatonin tablet 3 mg once daily, Thiamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Conduct Problems
Parent Preferences and Family Engagement in a Conduct Problems Prevention Program
The purpose of this study is to gain a better understanding of family preferences for and engagement in services.
- Trial name
- NCT02432014
- Testing
- PMTO-PTC Group clinic-based, PMTO Individual home-based, PMTO Individual clinic-based
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- University of Minnesota
Child Behavior Problem, Disruptive Behavior
Pilot Study of Cognitive Behavior Therapy With Role-plays in Virtual Reality for Children With Behavior Problems
The main aim of this small pilot trial is to evaluate preliminary effects and feasibility of the child intervention YourSkills for child disruptive behavior (e.g., enhanced anger or aggressive behavior) when evaluated in Sweden…
- Conditions
- Child Behavior Problem, Disruptive Behavior, Oppositional Defiant Disorder, Conduct Problems
- Trial name
- NCT06559800
- Testing
- YourSkills: Cognitive behavioral therapy for children/youth with role-plays in virtual reality
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Type 1 Diabetes (T1D)
Cognitive Function and Mental Health in Children and Youth With Type 1 Diabetes (T1D)
The Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI), Pune, a Center of Excellence in type 1 diabetes (T1D), has extensive experience in studying prospective cohorts with high follow-up rates.
- Trial name
- DMBCOG (NCT07164768)
- Where
- India
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Anxiety Disorders and Symptoms, Depressive Symptoms
Transdiagnostic, Indicated Preventive Intervention for Adolescents At High Risk of Emotional Problems W/Add-On Modules
PROCARE is a preventive intervention that has shown its effectiveness in selective prevention to reduce young people's risk of developing emotional problems.
- Trial name
- PROCARE-I+ (NCT06350760)
- Testing
- Active control condition, PROCARE-I+ 8-session
- Where
- 3 sites in Spain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Alcohol Consumption, Alcohol; Harmful Use
Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems
Alcohol is contributing to many health problems and disorders, as well as accidents and social problems. Alcohol consumption has been on the rise the past 25 years, especially in Norway.
- Conditions
- Alcohol Consumption, Alcohol; Harmful Use, Health Risk Behaviors, Alcohol Dependence
- Trial name
- NCT04164940
- Testing
- Brief alcohol intervention
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- Helse Stavanger HF
Depressive Disorder, Treatment-Resistant, Memory Deficits
SAINT® Therapy for Memory Problems in Older Adults With Treatment-Resistant Depression
The goal of this clinical trial is to learn whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®), a type of transcranial magnetic stimulation (TMS), is safe and may improve memory and thinking in adults aged…
- Trial name
- NCT07876908
- Testing
- Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®) with the Magnus Neuromodulation System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BrainHealth Solutions, Inc.
Dual Diagnosis, Alcohol Use Disorder
The 15-Mental Project: Implementation and Evaluation of the 15-Mental in a Mental Health Hospital Setting
The present project will implement and evaluate the effectiveness of a novel, but simple model for addressing and treating alcohol problems among patients admitted to outpatient treatment at mental health hospitals, called the…
- Conditions
- Dual Diagnosis, Alcohol Use Disorder, Hazardous Alcohol Use, Screening and Brief Intervention
- Trial name
- NCT07728968
- Testing
- 15-Mental.
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Alcohol-related Disorders, Alcohol Drinking
Medication and Counseling for Controlled Drinking (Project SMART)
The purpose of this study is to study the effectiveness of medication and specialized psychotherapy in helping gay and bisexual men who do not want to quit drinking learn how to reduce their drinking to healthier levels.
- Conditions
- Alcohol-related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
- Trial name
- NCT00444418
- Testing
- Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Anxiety, Depression
Factorial Optimization Trial to Test Effects of Coping Intervention Components
This study will identify components for inclusion in a coping intervention package to reduce mental health problems among children exposed to high interparental conflict after parental separation/divorce.
- Conditions
- Anxiety, Depression, Coping Skills, Emotional Problem
- Trial name
- NCT05822687
- Testing
- Education, Reappraisal Coping, Distraction Coping
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Arizona State University
Sleep Quality, Sleep Health
Clinical Study to Assess a Dietary Supplement on Sleep Health and Quality
The primary objective of this study is to evaluate the effects of a proprietary oral supplement on the sleep health and quality of people with sleep problems. It is a double-blinded placebo-controlled crossover clinical study.
- Trial name
- NCT05368909
- Testing
- Sleep Supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Dementia
Perceptions Regarding Investigational Screening for Memory Problems in Primary Care
The purpose of this study is to conduct a cross-sectional survey of primary care patients to better understand their perceptions of the risks and benefits of a screen and subsequent diagnostic confirmation of dementia.
- Trial name
- PRISM-PC (NCT00759252)
- Where
- United States
- Volunteers
- 954 people, healthy volunteers welcome
- Sponsor
- Indiana University
Alcohol-Related Disorders, Alcohol Use Disorders
Messaging Interventions to Reduce Alcohol Problems Project
The study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in reducing their alcohol consumption.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- MIRAP (NCT03695653)
- Testing
- Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO)
- Where
- United States
- Volunteers
- 730 people
- Sponsor
- Partnership to End Addiction
Problem Behavior, Aggression
Mind-Body Skills Groups for Behavioral and Emotional Problems in War-Traumatized Male Adolescents in Gaza
The purpose of this study is to determine whether war-traumatize male adolescents with behavioral and emotional problems who participate in mind-body skills groups will have improvement in behavioral and emotional problems…
- Conditions
- Problem Behavior, Aggression, Posttraumatic Stress Disorder
- Trial name
- NCT02671487
- Testing
- Mind-Body Skills Groups
- Where
- Palestinian Territories
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
Infant Regulatory Problems, Regulatory Problems in Infancy
Developing and Testing a Preventive Primary Care Parenting Intervention to Strengthen Parent-Infant Co-Regulation in Families Experiencing Early Regulatory Difficulties
The goal of this randomized controlled trial is to evaluate the effectiveness of a structured parenting support program for families with young infants experiencing early regulatory difficulties.
- Conditions
- Infant Regulatory Problems, Regulatory Problems in Infancy, Parental Stress, Parental Self-efficacy
- Trial name
- NCT07541716
- Testing
- Structured early parenting support program, called "Eat, sleep, cry - repeat"
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universiteit Antwerpen