Clinical trials: Mental Status Change
Delirium
Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients
The purpose of this chart review study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be associated with a lower…
- Trial name
- NCT00417664
- Testing
- Dexmedetomidine, Propofol, Midazolam
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Status Epilepticus, Non-Convulsive Status Epilepticus
Point-of-care EEG in the Pediatric Emergency Department
The researchers investigate the use of a simplified electroencephalogram (point-of-care EEG) in the pediatric emergency department for children with impaired consciousness or an ongoing epileptic seizure ("status epilepticus").
- Conditions
- Status Epilepticus, Non-Convulsive Status Epilepticus, Altered Mental Status
- Trial name
- NCT05418634
- Testing
- point of care EEG
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Children's Hospital, Zurich
Mental Status Change
Sun-Kissed Serenity: Morning Rays for a Brighter Mind
Sun-Kissed Serenity: Morning Rays for a Brighter Mind is a 30-day dawn rendezvous with nature. Participants are asked to stand outside for 15 minutes each morning, track progress with surveys, and support mental health with…
- Trial name
- NCT07256574
- Testing
- Morning sunlight
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Mental Status Change, Labor Pain
The Effect of Medical Clowning During Labor
Women during their first labor will be offered the assistance of a medical clown. Their experience will be compared after delivery with that of primiparae who were not helped by a medical clown.
- Trial name
- MedClown (NCT03167567)
- Testing
- Presence of a medical clown during labor
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Alzheimer's Disease, Mild Cognitive Impairment
Observational Study of Cognitive Outcomes for Subjects Who Have Had Prior PET Amyloid Imaging With Florbetapir F 18 (18F-AV-45)
The primary objective of this protocol is to determine if brain amyloid imaged with florbetapir F 18 (18F-AV-45) PET scans is predictive of progressive cognitive impairment during the subsequent 36 months for groups of: normal…
- Trial name
- NCT00857506
- Testing
- florbetapir F 18
- Where
- 8 sites in United States
- Volunteers
- 152 people
- Sponsor
- Avid Radiopharmaceuticals
Sleep Bruxism, Hypertension
Selected Disorders and Sleep Bruxism
Sleep apnea is a common and serious health problem in the Polish population. According to epidemiological data problem concerns about 7% of the adult population. The most common sleep disorder is obstructive sleep apnea (OSA).
- Conditions
- Sleep Bruxism, Hypertension, Thyroid Dysfunction, Mental Status Change
- Trial name
- NCT03083405
- Testing
- Opipramol
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Mild Cognitive Impairment, Subthreshold Depression
A One-year Trajectory of Depression Status Changes in Older Adults With MCI and SD: a Longitudinal Cohort Study
The purpose of this study is to investigate the one-year trajectory of changes in depression status in older adults with mild cognitive impairment and subthreshold depression, and to explore relevant risk factors for predicting…
- Conditions
- Mild Cognitive Impairment, Subthreshold Depression, Older Adults
- Trial name
- NCT06308627
- Where
- China
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Healthy
Posturing Effects on Perception of Time and Perceptions of the Provider-Patient Interaction in the Emergency Department
Study Objective: To examine the perceptions of time spent at the bedside; perceptions of bedside manner; and patient perceptions of the provider-patient interaction offered by emergency providers when they sit versus when they…
- Trial name
- NCT00170105
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nonconvulsive Status Epilepticus, Subclinical Seizure
EEG Cap for Identification of Non-Convulsive Status Epilepticus
Altered mental status (AMS) is one of the most common reasons for inpatient neurology consultation. Non-convulsive status epilepticus (NCSE) is frequently on the differential diagnosis of the patient with AMS.
- Conditions
- Nonconvulsive Status Epilepticus, Subclinical Seizure, Altered Mental Status, Nonepileptic Seizures
- Trial name
- NCT03138876
- Testing
- EEG Cap, Anti-seizure medication, Standard EEG
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Altered Mental Status
Diagnostic Yield and Influence on Length of Stay of Brain Computed Tomography for Elderly Patients With Altered Mental Status in an Emergency Setting
The confusional syndrome is defined by the acute or subacute onset of a deficit syndrome (temporo-spatial disorientation, memory and concentration disorders, abnormal behavior, impairment of intellectual efficiency, fluctuation…
- Trial name
- DISCUSS-CT (NCT04929704)
- Where
- France
- Volunteers
- 470 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Alzheimer's Disease
Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline
This study is designed to determine the effectiveness of florbetapir (18F) in changing patient management and to evaluate the association between scan status and cognitive decline.
- Trial name
- NCT01703702
- Testing
- florbetapir (18F)
- Where
- 57 sites in United States, France and 1 more
- Volunteers
- 641 people
- Sponsor
- Avid Radiopharmaceuticals
COVID-19
Do EEG and Neurocognitive Assessments Correlate With COVID Brainfog Symptoms?
Since the neurologic symptoms of some COVID patients ('brain fog') resemble those of patients with concussion, the aim of this study is to identify EEG and cognitive function changes in COVID patients.
- Trial name
- NCT05303116
- Testing
- Brainscope modified EEG and cognitive testing
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Musculoskeletal Disease, Obesity
Healthy Life Centers - Municipal Health Care Service for Lifestyle Changes - a Multicenter Intervention Study
A Healthy Life Center (HLC, 'Frisklivssentrale') is a public community-based health service providing lifestyle support programs for physical activity, smoking cessation and diet, to inhabitants with increased risk for…
- Conditions
- Musculoskeletal Disease, Obesity, Psychological Disorder
- Trial name
- NCT03026296
- Testing
- Healthy Life Center
- Where
- 4 sites in Norway
- Volunteers
- 1,022 people
- Sponsor
- Norwegian University of Science and Technology
Sleep Bruxism, Sleep Disorder
Relationship Between Selected Parameters and Bruxism
Bruxism is a common phenomenon. It is estimated that its prevalence in the adult population is 8-31%. Bruxism occurring during sleep is the activity of the masticatory muscles that appear during sleep, which can be rhythmic or…
- Conditions
- Sleep Bruxism, Sleep Disorder, Psychosomatic Disorder, Pain
- Trial name
- WMU1/2019 (NCT04214561)
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Hepatic Encephalopathy, Cirrhosis
Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy.
This study is being done to find out if the laxative polyethylene glycol (also known as GoLYTELY® or Miralax®) can treat your hepatic encephalopathy (confusion due to your liver disease and/or cirrhosis) better and/or more safely…
- Conditions
- Hepatic Encephalopathy, Cirrhosis, Portosystemic Encephalopathy, PSE
- Trial name
- PSE (NCT01283152)
- Testing
- Polyethylene glycol 3350-electrolyte solution (GoLYTELY®), Lactulose
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Pain, Postoperative Vomiting and Nausea
Efficacy Side-effect Score (ESS): Development and Evaluation of a New Tool for Patients After Surgery
We hypothesized that better control of postoperative pain treatment and its side effects by monitoring ESS might influence the degree of mobility and morbidity in surgical patients and consequently reduce LOS.
- Conditions
- Postoperative Pain, Postoperative Vomiting and Nausea, Postoperative Complications, Mental Status Changes Postoperative
- Trial name
- ESScore (NCT02143128)
- Testing
- Efficacy Safety Score, Verbal Numeric Rating Scale
- Where
- 2 sites in Kazakhstan, Russia
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- Vestre VikenHF Kongsberg Sykehus
Status Epilepticus, Altered Level of Consciousness
eegCap Application in Paediatrics wiTh redUced GCS in REsus
Children frequently present with altered or reduced consciousness levels to emergency departments. By using EEG monitoring, subclinical seizure activity may be detected, leading to earlier pharmacological intervention and…
- Conditions
- Status Epilepticus, Altered Level of Consciousness, Non-epileptic Seizures, Epilepsy
- Trial name
- CAPTURE (NCT05259891)
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University College Cork
Artificial Respiration, Consciousness Disorders
Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness
The purpose of this study is to determine if a weaning strategy from artificial ventilation governs by respiratory behaviour status assessed by our method is safe enough.
- Conditions
- Artificial Respiration, Consciousness Disorders, Wearing Off Effect
- Trial name
- ORGAR (NCT00700869)
- Testing
- mechanical ventilation
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Status Epilepticus, Seizure
EEG in In-hospital Patients With Seizure or Altered Mental State
In Kuopio University Department of Clinical Neurophysiology there have been designed a fast EEG electrode, that is suitable for acute emergency use.
- Conditions
- Status Epilepticus, Seizure, Altered Mental Status
- Trial name
- NCT02383745
- Testing
- Acute EEG with fast EEG electrode
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Kuopio University Hospital