Clinical trials: Mental Stress
Autism
Autism in Adult Patients and the Effects on Caregivers
Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s…
- Trial name
- NCT00367107
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Posttraumatic Stress Disorder, Depression
A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
In the framework of the epidemiological study, local psychologists are trained in Butare in carrying out diagnostic interviews with orphans and widows who experienced the Rwandan genocide.
- Conditions
- Posttraumatic Stress Disorder, Depression, Prolonged Grief Disorder
- Trial name
- NCT00553956
- Testing
- Narrative Exposure Therapy/Interpersonal Psychotherapy
- Where
- Rwanda
- Volunteers
- 150 people
- Sponsor
- University of Konstanz
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Symptoms and Mechanisms of Child Psychiatric Disorders
In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present…
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Severe Irritability
- Trial name
- NCT05049356
- Where
- 2 sites in Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Mental Health, Psychological Trauma
Pathway-Matched Resilience-Oriented Therapy in Rwanda
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (RoT), a culturally adapted group-based psychosocial intervention for post-genocide Rwanda.
- Conditions
- Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression
- Trial name
- RoT-CRT (NCT07621731)
- Testing
- Resilience-Oriented Therapy - Emotion-Regulation Variant, Resilience-Oriented Therapy - Identity-Development Variant, Resilience-Oriented Therapy - Behavioural Self-Management Variant
- Where
- 5 sites in Rwanda
- Volunteers
- 427 people
- Sponsor
- Alexandros Lordos, PhD
Tobacco Use Cessation, Tobacco Use Disorder
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers.
- Trial name
- NCT00129272
- Testing
- Bupropion-SR
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Dementia, Caregivers
VA Cultivating Access to Resources, Education, and Skills for Dementia Caregivers
The purpose of this study is to study the effects of an education and skill-building intervention on family caregivers of Veterans with dementia.
- Conditions
- Dementia, Caregivers, Neurodegenerative Diseases, Brain Diseases
- Trial name
- VACARES (NCT02106065)
- Testing
- Education and Skill-Building Rehabilitation (ESBR), Supplemental Education Materials
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stress, Psychological Factors
Body Awareness Therapy in High Stressed Young Adults: Effects on Function, Balance, Sleep and Mood
Body Awareness Therapy (BAT) is a holistic approach to human movement that considers the physical, physiological, psychological, and existential aspects of human existence.
- Conditions
- Stress, Psychological Factors, Sleep, Postural Balance
- Trial name
- NCT07045792
- Testing
- Body Awareness Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Musculoskeletal Disorder, Anxiety Disorders
A Multicentre Randomised Controlled Trial of the Norwegian Health in Work Service. The NSAC Efficacy Study
The Norwegian Sickness Absence Clinic (NSAC) is a publicly funded specialist outpatient health service, which is uniquely available for the work force.
- Conditions
- Musculoskeletal Disorder, Anxiety Disorders, Depression, Fatigue
- Trial name
- NSAC (NCT05310695)
- Testing
- NSAC - rapid, NSAC - ordinary, NSAC - active control
- Where
- 5 sites in Norway
- Volunteers
- 2,500 people
- Sponsor
- Nordlandssykehuset HF
Opioid Use Disorder, Intimate Partner Violence (IPV)
Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery
Using a hybrid type 1 effectiveness-implementation approach, this study aims to evaluate the impact of a novel stepped care model ("PCT+2HOPE") versus treatment as usual (TAU) on increasing retention in community-based medication…
- Conditions
- Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
- Trial name
- STRONGER (NCT07115030)
- Testing
- PCT+2HOPE
- Where
- 3 sites in United States
- Volunteers
- 532 people
- Sponsor
- Yale University
PTSD
Peer-Delivered Whole Health Coaching for Veterans With PTSD
The investigators are evaluating a service called peer-delivered Whole Health Coaching to understand how it can help Veterans with PTSD.
- Trial name
- NCT03364192
- Testing
- Whole Health Coaching
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Insomnia
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and…
- Conditions
- Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress
- Trial name
- NCT05663034
- Testing
- Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Neuropathic Pain, PTSD
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants.
- Trial name
- NCT06414356
- Testing
- Ketamine, Magnesium sulfate, Ketamine + Magnesium sulfate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Margaux M. Salas, PhD
Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder
Back on My Feet: Emotional Recovery From Fall Injury
We will compare two programs that are designed to help older adults who have had fall injuries manage anxiety and improve their level of functioning.
- Conditions
- Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder, Fear of Falling
- Trial name
- NCT01998945
- Testing
- Exposure-based Cognitive Behavioral Therapy, Relaxation Training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Weill Medical College of Cornell University
PTSD, Suicidal Ideation
Experiential Avoidance in Combat Veterans With and Without Posttraumatic Stress Disorder
This study plans to examine if symptoms of PTSD affect how Veterans who have served in combat think and react to certain information, and whether or not this has an influence on suicidal thoughts.
- Trial name
- NCT01652430
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Stress Disorders, Post-Traumatic, Depression
Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress
The primary purpose of this study is to test whether and how cognitive-behavioral therapy for insomnia (CBTi), a well-supported and highly effective insomnia treatment, may directly improve Posttraumatic Stress Disorder (PTSD)…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Sleep
- Trial name
- NCT01743339
- Testing
- Cognitive Behavioral Therapy, Control
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Rochester
Caregiver Burden
A Study on the Relationship Between Caregiver Burden, Resilience, and Sleep Quality in Individuals Providing Care for Bedridden Patients
This observational study aims to examine the relationship between caregiver burden, psychological resilience, and sleep quality in individuals providing care for bedridden patients, particularly in the context of palliative care.
- Trial name
- Caregiver (NCT07131930)
- Testing
- Caregiver Burden, Psychological Resilience, Sleep Quality
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- UĞUR UZUN
Acute Stress Reaction
Promoting Improved Functioning Among People Experiencing Stressful Situations
The iCOVER intervention was developed to rapidly restore functioning in individuals experiencing an Acute Stress Reaction (ASR). iCOVER is undergoing widespread adoption but has not been tested for efficacy.
- Trial name
- iCOVER (NCT06482567)
- Testing
- iCOVER, Physical Presence with Reassurance
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders
Body Therapy for War Veterans With Post Traumatic Stress Disorder (PTSD)
The present study is a randomized, controlled trial that compares a certain type of body therapy, called ManuVision, to treatment as usual (TAU) in war veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders, Behavioral Symptoms, Depression
- Trial name
- NCT03777800
- Testing
- Body therapy, Treatment as usual
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Southern Denmark
Anxiety, Pain
The Effectiveness of Stress Ball in Managing Anxiety and Pain During Prostate Biopsy
This study aimed to determine the effectiveness of stress ball application in the management of anxiety and pain during prostate biopsy.
- Conditions
- Anxiety, Pain, Prostate Biopsy
- Trial name
- NCT07101172
- Testing
- stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hitit University
Aggression, Stress
The Therapeutic Effects of Equine-Assisted Psychotherapy
Equine-assisted interventions (EAI) are an emerging form of alternate psychotherapy that has been increasingly found to produce improvements in various treatment outcomes.
- Conditions
- Aggression, Stress, Psychopathy, Empathy
- Trial name
- EAP (NCT04200612)
- Testing
- Equine-Assisted Psychotherapy, Equine-Assisted Activities
- Where
- Singapore
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Chua Yi Rong Shawn
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