Clinical trials: Mental Stress
Acute Stress Disorder
Psychological Interventions in Children After Road Traffic Accidents or Burns
Within a randomized controlled design the effects of a brief early psychological intervention (child, parents) after road traffic accidents or burns shall be examined in a sample of 120 children and adolescents (aged 2 to 16…
- Trial name
- PICARTA-B (NCT01085370)
- Testing
- Early psychological intervention
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- University Children's Hospital, Zurich
Burnout, Anxiety
Mental Health Outcomes and Variations in Exercise in Residents
The goal of this observational study is to learn about the relationship between physical activity levels and mental health outcomes in French medical residents.
- Conditions
- Burnout, Anxiety, Depression Anxiety Disorder, Physical Activity and Wellbeing
- Trial name
- MOVE-Res (NCT07380074)
- Testing
- Physical Activity and Mental Health Outcomes Assessment
- Where
- France
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Post Traumatic Stress Disorder, Major Depressive Disorder
Accelerated TMS to a Novel Brain Target in MDD and PTSD
This is a Clinical Trial designed to evaluate novel transcranial magnetic stimulation (TMS) methods for treating depression/PTSD. TMS is an FDA-approved procedure for treatment-resistant depression.
- Trial name
- NCT03114891
- Testing
- Transcranial Magnetic Stimulation (TMS), Task, fMRI-guided TMS target
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Anxiety Disorders, Depression
Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging
The investigators are developing and then testing whether Mindfulness-Based Stress Reduction, a group-based instruction for increasing mindfulness, reduces anxiety and depressive symptoms and improves cognitive functioning in…
- Trial name
- NCT01693874
- Testing
- MBSR, control (health education)
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Washington University School of Medicine
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Psychological Stress
With-Me - Technology-Aided Phone Coaching for Occupational Health Study
The purpose of this study is to examine whether the technology (web-based coaching, profiling and suggestion tool) brings added value to the traditional phone coaching in occupational health context.
- Trial name
- NCT02445950
- Testing
- Technology-aided phone wellness counselling, Phone wellness counselling
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VTT Technical Research Centre of Finland
Posttraumatic Stress Disorder
Randomized Trial of Prolonged Exposure for the Treatment of Posttraumatic Stress Disorder (PTSD)
This project will examine the impact of PE therapy for the treatment of PTSD with a sample of Latinos. The need to provide effective treatment to Spanish-speaking Latinos with PTSD is critical given the high prevalence of PTSD…
- Trial name
- NCT02134691
- Testing
- Prolonged Exposure, Applied Relaxation
- Where
- Puerto Rico
- Volunteers
- 98 people
- Sponsor
- University of Puerto Rico
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Post Traumatic Stress Disorder
Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD
The goal of this exploratory, mixed-method design study is to gather qualitative and quantitative data obtained through interviews and questionnaires with veterans who are currently enrolled at the VA for healthcare.
- Trial name
- PMATAVP (NCT05895318)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albany Research Institute, Inc.
Delirium, Critical Illness
Goal-Directed Sedation in Mechanically Ventilated Infants and Children
Ventilated pediatric patients are frequently over-sedated and the majority suffer from delirium, a form of acute brain dysfunction that is an independent predictor of increased risk of dying, length of stay, and costs.
- Conditions
- Delirium, Critical Illness, Sedation Complication, Executive Dysfunction
- Trial name
- mini-MENDS (NCT04801589)
- Testing
- Dexmedetomidine, Midazolam
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- Vanderbilt University Medical Center
Stress Disorders, Post-Traumatic
Gene Expression Correlates of Post-Traumatic Stress Disorder (PTSD) Symptom Change After EFT (Emotional Freedom Techniques)
The purpose of the study is to measure the change in psychological symptoms and gene expression in war veterans after a series of 10 EFT coaching sessions.
- Trial name
- NCT01250431
- Testing
- EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Autonomic Nervous System Imbalance, Heart Rate Variability (HRV)
Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary outcomes of a heart rate variability biofeedback (HRVB) intervention among adults with opioid use disorder (OUD) receiving residential…
- Conditions
- Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques
- Trial name
- NCT07361731
- Testing
- Heart rate variability biofeedback
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Arizona State University
Ketogenic Diet, Drug Resistant Epilepsy
Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy
The goal of this clinical trial was to evaluate the effectiveness of a low glycemic index diet (LGID) on seizure frequency, oxidative stress markers and quality of life in children with drug-resistant epilepsy.
- Conditions
- Ketogenic Diet, Drug Resistant Epilepsy, Oxidative Stress, Quality of Life
- Trial name
- NCT06432231
- Testing
- Low glycemic index diet treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Izmir Katip Celebi University
Post Traumatic Stress Disorder
Computer Assisted Lessening of Intrusive Memories in the Emergency Department
During the COVID-19 pandemic, clinical staff working in frontline NHS hospital and pre-hospital departments (e.g. emergency department, intensive care unit, ambulance service) are being faced with difficult and stressful…
- Trial name
- CALM-ED (NCT04769999)
- Testing
- Simple cognitive task
- Where
- 3 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Oxford
Kava, Anxiety
Effect of Kava on Anxiety and Stress in Cancer Survivors
This is a pilot, two-arm, randomized, blinded, placebo-controlled cross-over clinical trial to study the safety and effect of 14 days of kava on anxiety and physiologic stress in survivors of cancer and its treatment.
- Conditions
- Kava, Anxiety, Stress, Cancer
- Trial name
- NCT06213298
- Testing
- Kava
- Where
- United States
- Sponsor
- Masonic Cancer Center, University of Minnesota
Neurological Disorders, Mental Health
ACT for Mental Health in Neurological Disorders
The goal of this clinical trial is to examine the efficacy of this manual for mental health in people with mixed neurological disorders, including post-COVID.
- Conditions
- Neurological Disorders, Mental Health, Executive Function (Cognition), Depression/Anxiety
- Trial name
- NCT06897553
- Testing
- ACT-based group therapy
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Bielefeld University
Common Mental Disorders, Depression
Integrated Mental Health Care and Vocational Rehabilitation to People With to Common Mental Disorders
The purpose of this study is to investigate the efficacy of an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of depression, stress, anxiety, personality- and functional…
- Conditions
- Common Mental Disorders, Depression, Anxiety, Personality Disorders
- Trial name
- IBBIS II (NCT04432129)
- Testing
- IBBIS II, Service as Usual
- Where
- Denmark
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Chronic Obstructive Pulmonary Disease
Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial
Background: Informative and supportive nursing care is essential to reduce complications and improve outcomes in Chronic Obstructive Pulmonary Disease (COPD) patients treated with Non-Invasive Ventilation (NIV).
- Trial name
- NCT04834037
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Earthquake, Stress Disorders, Post-Traumatic
The Effect of Exercise on Post-traumatic Stress Disorder and Sleep Quality in Individuals Affected by the 2023 Kahramanmaraş Earthquakes
Natural disasters can have adverse impacts on both physical and mental health. Post-traumatic stress disorder (PTSD) and sleep disorders are among the most common problems seen after natural disasters.
- Trial name
- NCT06388876
- Testing
- Exercise, lifestyle advice
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Nursing Home, Dementia
San Rocco Study: Implementation of the Non-pharmacological Therapies for People With Dementia Living in Nursing Home
The goals of this clinical trial are 1) to estimate the number of professional caregivers and the time spent to carry out the non-pharmacological therapies for people with dementia and 2) to evaluate differences between…
- Conditions
- Nursing Home, Dementia, Staff
- Trial name
- NCT05814276
- Testing
- Training on non-pharmacological therapies' methodology
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Associazione Ginco Ticino
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