Clinical trials: Mental Stress
Posttraumatic Stress Disorder
Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD
The purpose of this study is to conduct a randomized controlled trial to compare group and individual CPT-C for the treatment of PTSD in OIF/OEF military personnel.
- Trial name
- NCT02173561
- Testing
- Group Cognitive Processing Therapy-Cognitive Only, Individual Cognitive Processing Therapy-Cognitive Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Post-Traumatic Stress Disorders, Obsessive-Compulsive Disorder
Cognitive Characteristics of PTSD Patients With OCD
Cognitive profile of patients who suffer both from PTSD and OCD, as compared to those who suffer from PTSD or OCD without other comorbidity.
- Trial name
- NCT00294970
- Where
- Israel
- Volunteers
- 76 people
- Sponsor
- Sheba Medical Center
Coronary Artery Disease
The Effect of Stress Ball Application Before Coronary Angiography on Stress, Anxiety and Vital Signs
It aimed to examine stress, anxiety and resorting to life paths to enable researchers to contain this stress.
- Trial name
- NCT05867394
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Aysel Sesci
Trauma
Dexamethasone as an Immediate Intervention
To determine if a single dose of dexamethasone (5 mg) administered in the first 12 hours following a potentially traumatic event alters a) cortisol and FKBP5 RNA the next day in the periphery measured in saliva; b) FKBP5…
- Trial name
- NCT02753166
- Testing
- Dexamethasone
- Where
- United States
- Sponsor
- NYU Langone Health
Burnout, Professional, Negative Affect
Floatation Experience in Nurses and Physicians
The goal of this observational study is to monitor the floatation experience and continue the program as long as deemed important.
- Conditions
- Burnout, Professional, Negative Affect, Positive Affect, Wellbeing
- Trial name
- NCT05977894
- Testing
- Reduced Environmental Stimulation Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Perinatal Mental Health, Pregnancy Related
Mindfulness-Based Stress Reduction for Psycho-socially Vulnerable Pregnant Women.
The aim of the study is to address the need for a wider array of evidence-based and non-pharmacological options to improve mental health in a psycho-socially highly vulnerable group of pregnant women.
- Trial name
- NCT05300646
- Testing
- Prenatal mindfulness-based stress reduction
- Where
- 2 sites in Denmark
- Volunteers
- 238 people
- Sponsor
- University of Aarhus
Mental Health Wellness 1, Eating Behavior
Managing Our Relationship With Food and Eating
There is a need for population-level intervention research to address the impacts of the COVID-19 pandemic on disordered eating and unhealthy eating behaviours.
- Conditions
- Mental Health Wellness 1, Eating Behavior, Stress, Psychological, Eating Habit
- Trial name
- NOURISH (NCT04797689)
- Testing
- Trauma Informed Yoga, Trauma Informed Psychotherapy
- Where
- Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
PTSD
Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days
Veterans with posttraumatic stress disorder (PTSD) need more effective treatments. Existing options can have limited adherence and can be very time-consuming. As such, alternative interventions are needed.
- Trial name
- RAPID5 (NCT07167940)
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder, PTSD and Trauma-related Symptoms
TF-CBT for Autistic Youth Pilot Implementation - Open Pilot
Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms following trauma exposure.
- Conditions
- Autism Spectrum Disorder, PTSD and Trauma-related Symptoms, Autism, Trauma and Stressor Related Disorders
- Trial name
- NCT07420478
- Testing
- Trauma-Focused Cognitive Behavioral Therapy, modified for autistic youth
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mild Cognitive Impairment, Dementia Alzheimers
Protecting Alzheimer Caregivers Using Technology Through Staying Sharp
PROACTS is a Phase I/II study to assess the efficacy of AARP Staying Sharp online health program, focusing on the health of non-professional home-based caregivers of persons with Alzheimer's disease and related dementias (ADRD).
- Conditions
- Mild Cognitive Impairment, Dementia Alzheimers, Old Age; Dementia, Caregiver Burden
- Trial name
- PROACTS (NCT05260515)
- Testing
- Staying Sharp intervention
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Posttraumatic Stress Disorder
Group Written Exposure Therapy for Posttraumatic Stress Disorder
The goal of this clinical trial is to test if Written Exposure Therapy (WET) works well in a group setting in patients with post-traumatic stress disorder (PTSD).
- Trial name
- GWET (NCT05729789)
- Testing
- Group Written Exposure Therapy
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Neuro-Degenerative Disease, Dementia
Decreased Empathy and Emotion Recognition in Patients With Neurodegenerative Disease
This study evaluates an educational brochure tailored to caregivers of people with Alzheimer's disease, Parkinson's disease dementia, Lewy body disease, frontotemporal dementia, and vascular disease dementia.
- Conditions
- Neuro-Degenerative Disease, Dementia, Caregiver Burnout, Alzheimer Disease
- Trial name
- Empathy (NCT04635540)
- Testing
- Educational Brochure
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University Health Network, Toronto
Acceptability of Health Care
Blended Treatment för PTSD Feasibility Study
Feasibility and pilot study using within-group design with the aim of examining whether the blended psychological treatment for PTSD is acceptable for patients and therapists. 20 patients will be included and 4 therapists.
- Trial name
- NCT04881643
- Testing
- Trauma-focused cognitive behavioural therapy via a digital support
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Karolinska Institutet
Mental Health Issue, Musculoskeletal Pain
Sustainable UNiversity Life (SUN) Study
In 2017, Socialstyrelsen reported that mental ill-health in young adults had increased by almost 70% in the previous10 years. A 2014 report showed that 5% of men and 11% of women 18-24 years were diagnosed with depression or…
- Trial name
- SUN (NCT04465435)
- Testing
- Web-based self-report questionnaires, Focus Group Interviews
- Where
- Sweden
- Volunteers
- 4,262 people
- Sponsor
- Sophiahemmet University
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Adjustment Disorder, Anxiety
Online MBCT for Adjustment Disorder During COVID-19: Efficacy, Mechanisms, and RCT
This study tested a 4-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing adjustment disorder during the COVID-19 pandemic.
- Conditions
- Adjustment Disorder, Anxiety, Depressive
- Trial name
- NCT07128017
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), Progressive Muscle Relaxation (Internet-delivered), No Intervention - Waitlist Control
- Where
- Poland
- Volunteers
- 301 people
- Sponsor
- University of Warsaw
PTSD, Depression
Treatment of Depression in Patients With PTSD
Post-traumatic stress disorder is a mental health problem of enormous proportion within the VA system for both male and female veterans.
- Trial name
- NCT00013091
- Testing
- Self-management therapy; Psychoeducational group therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder, Dissociative Identity Disorder
Stabilizing Group Treatment of Complex Trauma: A Randomized Controlled Trial
The research project outlined in this proposal aims to investigate the effectiveness of stabilizing group treatment as an add-on to conventional treatment, for patients with Post Traumatic Stress Disorder (PTSD) or dissociative…
- Conditions
- Posttraumatic Stress Disorder, Dissociative Identity Disorder, Dissociative Disorder
- Trial name
- STAB (NCT02450617)
- Testing
- Conventional individual treatment, Stabilizing group treatment for PTSD, Stabilizing group treatment for Dissociative disorders
- Where
- Norway
- Volunteers
- 158 people
- Sponsor
- Modum Bad
Healthy, Anxiety
Neuromodulation of Brain and Emotional Responses to Psychological Stress
Investigators are conducting this study to test if temporarily and non-invasively stimulating the brain will affect the emotional response to stress in healthy participants.
- Trial name
- NUMBER (NCT06603064)
- Testing
- Active continuous theta burst stimulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
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