Clinical trials: Mental Test
Suicide Prevention
Validation and Testing of a Suicide Prevention Program to Improve Mental Well-Being Among Adolescents in Gilgit Baltistan, Pakistan: A Pre/Post-Intervention Protocol
Background Globally, around 800,000 people die annually by committing suicide with a disproportionate burden of 77% of these deaths occurring in low- and middle income countries.
- Trial name
- Protocol (NCT06721364)
- Testing
- Suicide prevention treatment
- Where
- Pakistan
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Alcohol Use Disorder (AUD), Alcoholism
Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer
Individuals with substance use disorders (SUD) have to cope with drug-related cues and contexts, which can affect instrumental drug seeking as shown with Pavlovian to instrumental transfer (PIT) paradigms in animals and humans.
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders, Smoking, Tobacco
- Trial name
- ReCoDe (NCT05992272)
- Testing
- fMRI imaging (BOLD), sMRI (structure), Trier Social Stress Test
- Where
- 2 sites in Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
ADHD, Attention
Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD)
Impaired WM is a central deficit in ADHD. A computerized training program, Cogmed, has been shown to increase WM capacity in children with ADHD.
- Trial name
- Cog-RAST (NCT01124721)
- Testing
- Cognitive training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Davis
Alzheimers Disease
Clinical Utility of Early vs. Late Blood Biomarker Testing for Alzheimer's Disease
The goal of this study is to evaluate whether use of the PrecivityAD2 blood biomarker assay with early result disclosure along with discretionary Precivity-ApoE proteotype testing will shorten the time to Alzheimer's Disease or…
- Trial name
- ADELAIDE (NCT06856681)
- Testing
- PrecivityAD2 - Early Testing, PrecivityAD2 - Delayed Testing
- Sponsor
- C2N Diagnostics
Autism Spectrum Disorders
Cortical Metrics Assessment Outcome Measure Development in Autism With Memantine Treatment
Specific Aim 1: Obtain proof of concept evidence that cortical metrics will change in response to treatment with Memantine extended release (XR)®, an agent that modulates n-methyl d-asptartate (NMDA) receptor activation, in…
- Trial name
- NCT02353130
- Testing
- Memantine-XR
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety Symptoms, Post-traumatic Stress Symptoms
Improving Student Mental Health Through a Universal Trauma-Informed Intervention
The goal of this trial is to identify the most effective ways for schools to deliver RAP Club, a universal school-based mental health intervention.
- Conditions
- Anxiety Symptoms, Post-traumatic Stress Symptoms, Depressive Symptoms, Behavioral Problems
- Trial name
- PPP (NCT07842432)
- Testing
- RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Battered Women
Effectiveness of a Telephone Intervention to Improve the Mental Health of Abused Women
The purpose of this study is to determine if a telephone social support and empowerment intervention is more effective than usual community services in improving the mental health of community-dwelling women abused by their…
- Trial name
- NCT01054898
- Testing
- advocacy intervention, usual community services
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Pathological Gambling
Testing Resources: Manual and Webinar Guided Treatment vs. Manual Guided Treatment
Research specific to women's gambling treatment needs is limited but suggests a critical need for women sensitive options and reduced barriers to access.
- Trial name
- NCT01743092
- Testing
- Webinar, Tutuorial workbook
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Centre for Addiction and Mental Health
Neurocognitive Disorder, Robotic Assisted Laparoscopic Radical Prostatectomy
The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases
The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the…
- Conditions
- Neurocognitive Disorder, Robotic Assisted Laparoscopic Radical Prostatectomy, Near Infrared Spectroscopy
- Trial name
- NCT06869304
- Testing
- Montreal Cognitive Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Major Depressive Disorder, Bipolar Disorder
Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)
Background: People with TRD are often helped by electroconvulsive therapy (ECT). But ECT can affect memory and thinking. Researchers want to study a treatment called TEST that uses less electricity.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Unipolar Major Depression
- Trial name
- NCT05172271
- Testing
- MagPro TMS Stimulator and coil, Thymatron(R) System IV, Magnetic Resonance Imaging Scanner
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- National Institute of Mental Health (NIMH)
Caregiver Burden, Dementia
Mobile App Intervention for Informal Dementia Caregivers
Informal caregivers of persons with dementia (PWD) usually experience elevated levels of caregiving burden and potential depression.
- Conditions
- Caregiver Burden, Dementia, Digital Health
- Trial name
- NCT05551533
- Testing
- Kampung Care App
- Where
- Singapore
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Institute of Mental Health, Singapore
Schizophrenia
A Clinical Study to Evaluate the Bioavailability Between Two Products Containing Paliperidone 100 mg in the Form of a Prolonged Release Suspension for Injection in Patients With Schizophrenia Who Are Already Stabilized in This Treatment
This clinical study will compare the equivalence of two products containing Paliperidone 100 mg in the form of a prolonged release suspension for injection in patients affected by schizophrenia who are already receiving this…
- Trial name
- NCT03425552
- Testing
- Paliperidone
- Where
- 3 sites in Jordan
- Volunteers
- 70 people
- Sponsor
- Pharmathen S.A.
Cigarette Smoking, Nicotine Dependence
Smokers' Response to Nicotine Dependence Genotyping
Innovative strategies to reduce adult smoking prevalence include using genetic information to motivate cessation and, ultimately, to tailor cessation pharmacotherapy.
- Trial name
- NCT01780038
- Testing
- Receipt of Genetic Results, No results given
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Erectile Dysfunction
Bioequivalence Study Comparing Two Test Products With One Reference Product, All Containing 5 mg Yohimbine
Type: Bioequivalence study in male healthy volunteers, therapeutical indication (erectile disfunction) not studied Products, dosage, and route of administration: Test 1: Yohimbin "Spiegel"® (Desma GmbH, Germany), tablet…
- Trial name
- NCT00975325
- Testing
- Yohimbine
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Walter Ritter GmbH & Co
Mental Health Issue, Mental Health Disorder
Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions
US residents who have obesity and sign the informed consent form and are screened and enrolled for this study. Participants who are enrolled complete a survey upon enrollment and are randomized into one of two arms.
- Conditions
- Mental Health Issue, Mental Health Disorder, Mental Health, Depression
- Trial name
- NCT06190184
- Testing
- VIOME Precision Nutrition Program, Control arm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Viome
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Depressive Symptoms, Depression
Efficacy of an Online Self-help Program for Negative Affect and Depression
The aim of the study is to test Body, breath \& mind (BBM, internet-based self-help program) for its efficacy in reducing depressive symptoms and improving quality of life.
- Trial name
- NCT05293691
- Testing
- Body, Breath & Mind, Moodgym
- Where
- Germany
- Volunteers
- 303 people
- Sponsor
- University of Witten/Herdecke
HIV, Substance Abuse
Women-Focused HIV Prevention in the Western Cape
The purpose of this study is to test the effectiveness of a woman-focused HIV prevention intervention combined with voluntary counseling and testing (VCT), compared to VCT only, and VCT combined with an attention-control…
- Conditions
- HIV, Substance Abuse, Violence
- Trial name
- WC-WHC (NCT00729391)
- Testing
- Woman-Focused Intervention (Women's Health CoOp), Nutrition (Attention-Control), VCT Only
- Where
- South Africa
- Volunteers
- 720 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Chronic Pain
The Effects of Water Temperature on the Cold Pressor Test
This current study is intended to be completed under the umbrella of the current GHUCCTS IRB- approved study "Opioid-Induced Hyperalgesia In Prescription Opioid Abusers: Effects of Pregabalin" (Lyrica study) (PRO00000669).
- Trial name
- NCT03083626
- Testing
- Cold pressor test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgetown University