Clinical trials: Mental and Behavioral Disorders
Major Depressive Disorder
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents; yet the neural underpinnings of perceived…
- Trial name
- NCT04788524
- Testing
- Computer Task Manipulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression, Stress
Effects of Landscapes on the Brain
There is an established consensus between researchers that the contact with natural environments has beneficial influence on mental health and well-being of people exposed to them.
- Conditions
- Depression, Stress, Anxiety Disorders
- Trial name
- NCT04210856
- Testing
- Contemplative landscape exposure
- Where
- Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Eating Disorder Symptom
Efficacy of Eat Breathe Thrive, a Yoga-Based Program
The purpose of this study is to evaluate the efficacy of the 7-week Eat Breathe Thrive (EBT) program which was designed to increase positive body image, awareness, self-regulation, and mindful eating habits.
- Trial name
- NCT03348345
- Testing
- Eat Breathe Thrive
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Substance Use Disorders
Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers
In recent years ketamine abuse becomes prevalent in youth in some Asian countries. Chronic ketamine abuse may lead to uropathology and cognitive impairments.
- Trial name
- NCT03644719
- Testing
- Cognitive behavioral skills training
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Nature, Human, Mental Health Wellness 1
Effects of Forest Bathing in Vancouver, B.C. Parks
This study aims to investigate environmental factors that influence people's responses to the Japanese practice of forest bathing in Vancouver, B.C. parks.
- Conditions
- Nature, Human, Mental Health Wellness 1, Stress, Psychological, Blood Pressure
- Trial name
- NCT05502588
- Testing
- Self-Guided Forest Bathing, Guided Forest Bathing
- Where
- 4 sites in Canada
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Human Immunodeficiency Virus, Depression
Community Home-based Care Intervention and Its Health Outcome in HIV-positive People
An intervention study was designed to examine the impact of impact of community home-based care intervention on mental health and treatment outcome in HIV-positive people.
- Conditions
- Human Immunodeficiency Virus, Depression, Stress, Anxiety
- Trial name
- HIV (NCT03505866)
- Testing
- Community home-based care intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Integrated Development Foundation Nepal
Maternal Health, Pregnancy
Understanding the Role of Doulas in Supporting People With PMADs
Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility.
- Conditions
- Maternal Health, Pregnancy, Delivery, Obstetric, Self Efficacy
- Trial name
- NCT05763537
- Testing
- Standard Doula Care Plus PMAD Intervention, Standard Doula Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Montana
REM Sleep Behavior Disorder, Neurodegeneration
Search for Biomarkers of Neurodegenerative Diseases in Idiopathic REM Sleep Behavior Disorder
This study is a prospective study with a mean of 7-year follow-up interval, aims to monitor the progression of α-synucleinopathy neurodegeneration by the evolution of prodromal markers and development of clinical disorders in…
- Trial name
- NCT04048603
- Where
- Hong Kong
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Breathing Exercises
The Effect of Diaphragmatic Breathing Exercise on Pain, Anxiety, and Depression
Background: After total knee replacement (TKR) surgery, patients often experience intense levels of pain, stress, and anxiety that can adversely affect postoperative recovery.
- Trial name
- NCT04225169
- Testing
- Breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Burnout, Insomnia
Improving the Mental Health and Well Being of Healthcare Providers Through the Transcendental Meditation Technique
The level of stress-related disorders experienced by Healthcare Providers (HCPs) has increased due to the recent COVID-19 Pandemic, impacting patient care and provider shortages.
- Conditions
- Burnout, Insomnia, Well Being
- Trial name
- NCT05239429
- Testing
- Transcendental Meditation Technique
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical and Cosmetic Research
Mental Stress, Myocardial Ischemia
Heart-brain-axis and Psychosocial Stress
The main study objective is to prospectively determine the influence of sex-related risk factors and psychosocial variables on neuronal stress responses and myocardial perfusion in a population of 64 female and male individuals…
- Conditions
- Mental Stress, Myocardial Ischemia, Sex Role, Gender
- Trial name
- NCT06345573
- Testing
- Mental stress
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Depression, Anxiety
A Gratitude Intervention App to Reduce Symptoms of Depression, Anxiety and Stress
The goal of this clinical trial is to examine whether a newly developed gratitude intervention app can effectively improve psychological functioning, as measured by depression, anxiety, and stress symptoms, positive and negative…
- Conditions
- Depression, Anxiety, Stress
- Trial name
- NCT06621745
- Testing
- Gratitude Intervention App
- Where
- Canada
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Depression
Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for Depression
This study will examine multiple carefully selected clinical and biological markers, using both existing state-of-the-art technologies as well as pioneering, innovative approaches.
- Trial name
- EMBARC (NCT01407094)
- Testing
- Sertraline, BupropionXL
- Where
- 4 sites in United States
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Autism Disorder, Language Development Disorders
Rural Autistic Individuals - Supporting Expression
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are…
- Conditions
- Autism Disorder, Language Development Disorders, ADHD, Typical Development
- Trial name
- RAISE (NCT07054866)
- Testing
- Speech-Gesture combinations
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montana State University
Sleep Disturbance, Attention Deficit
Sleep and Exposure to Screens of Digital Media Devices in Israel
The aims of this survey are to assess the relationships between exposure to screens of digital media devices, sleep patterns, and daily function such as subjective sleepiness and attention abilities in adult Israel population
- Trial name
- NCT03318302
- Testing
- Survey
- Where
- Israel
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Insomnia
Infant Behavioral Sleep Intervention: Comparative Efficacy
While frequent night awakenings in newborns are common and expected, an estimated 20-30% of older infants and toddlers have frequent problematic night wakings requiring parental intervention throughout the night.
- Trial name
- NCT03447665
- Testing
- Bedtime routine, Sleep schedule, Intervention (bedtime)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Insomnia, Nocturnal Awakening
Use Of The Dietary Supplement 5-ALA And Its Relationship With Sleep And Mood
PURPOSE: The purpose of this investigation is to determine if a relationship exists between the administration of a dietary supplement containing 5-ALA and sleep and mood.
- Conditions
- Insomnia, Nocturnal Awakening, Irritability, Coping Behavior
- Trial name
- NCT01508741
- Testing
- 5-Aminolevulinic Acid (5-ALA)
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Quality of Life, Antidepressive Agents
Study of the Effects of Plx on Bioparametric Measurements.
The main objective is to study the effects of the intake of a nutraceutical on health indicators, focused on sleep and stress, as well as cardiovascular (blood pressure...), circulating (cortisol) and body composition parameters…
- Conditions
- Quality of Life, Antidepressive Agents, Depression, Anxiety, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT05128812
- Testing
- PLX
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alicante
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