Clinical trials: Mental and Behavioral Disorders
Cigarette Smoking, Marijuana Abuse
Mobile Contingency Management for Marijuana and Tobacco Cessation
The purpose of this pilot project is to pilot-test a combined cannabis and smoking cessation treatment. The intervention combines mobile technology with behavioral strategies, counseling, and medications.
- Trial name
- NCT02869451
- Testing
- bupropion, transdermal nicotine patch, Nicotine polacrilex
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Sudden Cardiac Death
CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death
Despite major progress in molecular and phenotypic characterization of primary electrical disorders, many (aborted) sudden cardiac deaths (SCD) occur in young victims without identifiable abnormalities.
- Trial name
- IQARE-SCD (NCT03387072)
- Testing
- Non interventional study
- Where
- 4 sites in France
- Volunteers
- 394 people
- Sponsor
- Nantes University Hospital
Elderly, Muscle Loss
Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
This study refers to the supplementation of PS23 in human experiments to help the elderly maintain muscle mass, delay muscle loss, promote physical activity, and delay the occurrence of disability and debilitation in elderly…
- Conditions
- Elderly, Muscle Loss, Depression, Anxiety
- Trial name
- NCT06062472
- Testing
- Probiotics, heat-treated of Lactobacillus paracasei HT-PS23
- Where
- Taiwan
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Chi-Chang Huang
Cerebral Palsy, Sleep Disorders in Children
Sleep Quality and Caregiver Burden in Children With Cerebral Palsy
Cerebral palsy (CP) is a lifelong condition affecting movement and posture, often requiring substantial care from family members.
- Conditions
- Cerebral Palsy, Sleep Disorders in Children, Caregiver Burden, Sleep Quality
- Trial name
- CP-SLEEP (NCT07168577)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selim Sezikli
Depression, Major Depressive Disorder
The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression
Many people with depression are treated with a serotonin-specific reuptake inhibitor anti-depressant (SSRI) and feel 'better'. Although many people feel 'better', they do not feel completely 'well'.
- Conditions
- Depression, Major Depressive Disorder, Unipolar Depression
- Trial name
- NCT00125957
- Testing
- Wellbutrin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mclean Hospital
Behavior, Child
Teacher Child Interaction Training (TCIT): Randomized Control Trial
This study is being conducted to evaluate the effects of TCIT on child development, child behavior, and teacher use of skills in the classroom.
- Trial name
- NCT04000230
- Testing
- TCIT, Booster
- Where
- 4 sites in United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dementia
Development and Effectiveness of a User-centered Mobile Application for Informal Caregivers of People Living With Dementia: Randomized Controlled Trial
The research shows that the mobile application developed for informal caregivers of people living with dementia affects caregivers' care burden, quality of life; It was planned as a mixed-type, randomized controlled study to…
- Trial name
- NCT06179667
- Testing
- Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Autism
Autism in Adult Patients and the Effects on Caregivers
Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s…
- Trial name
- NCT00367107
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Posttraumatic Stress Disorder, Depression
A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
In the framework of the epidemiological study, local psychologists are trained in Butare in carrying out diagnostic interviews with orphans and widows who experienced the Rwandan genocide.
- Conditions
- Posttraumatic Stress Disorder, Depression, Prolonged Grief Disorder
- Trial name
- NCT00553956
- Testing
- Narrative Exposure Therapy/Interpersonal Psychotherapy
- Where
- Rwanda
- Volunteers
- 150 people
- Sponsor
- University of Konstanz
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Symptoms and Mechanisms of Child Psychiatric Disorders
In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present…
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Severe Irritability
- Trial name
- NCT05049356
- Where
- 2 sites in Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Mental Health Wellness 2, Health Behavior
Tracking Our Lives Study
College women are at risk for eating disorders, which have profound health impacts. Cross-sectional studies have shown that the use of dietary self-monitoring is associated with eating disorder risk among college students.
- Conditions
- Mental Health Wellness 2, Health Behavior, Eating Disorders
- Trial name
- NCT04052529
- Testing
- Dietary self-monitoring
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Mental Health, Psychological Trauma
Pathway-Matched Resilience-Oriented Therapy in Rwanda
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (RoT), a culturally adapted group-based psychosocial intervention for post-genocide Rwanda.
- Conditions
- Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression
- Trial name
- RoT-CRT (NCT07621731)
- Testing
- Resilience-Oriented Therapy - Emotion-Regulation Variant, Resilience-Oriented Therapy - Identity-Development Variant, Resilience-Oriented Therapy - Behavioural Self-Management Variant
- Where
- 5 sites in Rwanda
- Volunteers
- 427 people
- Sponsor
- Alexandros Lordos, PhD
Tobacco Use Cessation, Tobacco Use Disorder
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers.
- Trial name
- NCT00129272
- Testing
- Bupropion-SR
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Ketoses, Metabolic, Ketogenic Dieting
Effect of Nutritional Ketosis on Alcohol Metabolism
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after…
- Conditions
- Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging
- Trial name
- KAM (NCT06065657)
- Testing
- Ketone Supplement, Control Diet, Ketogenic diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Attention Deficit Hyperactivity Disorder
Towards an Understanding of the Mechanism of Action of Methylphenidate in ADHD
Approximately 1-in-20 children worldwide have Attention Deficit Hyperactivity Disorder (ADHD), a condition associated with disabling inattention, hyperactivity and impulsivity.
- Trial name
- NCT05600881
- Testing
- Methylphenidate
- Volunteers
- 35 people
- Sponsor
- University of Dublin, Trinity College
Attention Deficit Hyperactivity Disorder
Community-Based Care for Minority Adolescents With ADHD: Improving Fidelity With Machine Learning-Assisted Supervision and Fidelity Feedback.
This project proposes to reduce disparities in care among disadvantaged racial/ethnic minority adolescents with ADHD by improving community therapist fidelity to evidence-based behavior therapy through a technology-assisted…
- Trial name
- NCT05135065
- Testing
- Artificial Intelligence-Assisted Supervision Protocol
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Seattle Children's Hospital
Transgenderism, Erectile Dysfunction
Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.
Transgender and gender diverse (TGD) individuals most often choose for phalloplasty as a means to create masculine external genitalia.
- Conditions
- Transgenderism, Erectile Dysfunction, Prosthesis Durability, Gender Dysphoria
- Trial name
- EROS (NCT05883553)
- Testing
- Usability and added value of device within sexual activity
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Aging, Addiction
Based-virtual Reality Diagnosis for Neuropsychiatric Diseases and Sleep/Wake Disorders
The objective of this research is to develop original virtual reality scenarios and/or new virtual reality equipments to evaluate or diagnose pathologies, such as attention deficit disorders or neuropsychiatric pathologies…
- Conditions
- Aging, Addiction, Attention Deficit Disorder With Hyperactivity, Sleep Disorders
- Trial name
- PHENOVIRTPSY (NCT02544295)
- Testing
- Clinical interview, Virtual reality task
- Where
- France
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Attention-Deficit Hyperactivity Disorder, Unspecified Type, Autism Spectrum Disorder
A Multi-dimensional Prospective Study to Discover Gene-microenvironment Interactions in Neurodevelopmental Disorders
This project is the first involving the two most common neurodevelopmental disorders, ASD and ADHD, as well as TDC to establish a multi-dimensional database (clinic, behavior, neurocognitive function, brain imaging, metabolomics…
- Trial name
- NCT04878575
- Testing
- ASD diagnosis, Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Alcohol Drinking, Heavy Drinking
Reset Challenge: Reducing High-risk Drinking for Cancer Prevention
This is a single-arm, non-randomized, prospective study to evaluate the feasibility and preliminary efficacy of a 30-day mobile Health (mHealth) Reset Challenge for reducing high-risk drinking.
- Conditions
- Alcohol Drinking, Heavy Drinking, Binge Drinking
- Trial name
- NCT07591428
- Testing
- 30-Day Alcohol Abstinence Challenge
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Oklahoma
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