Clinical trials: Mental and Behavioral Disorders
Pain, Fatigue
A Patient-Controlled Cognitive-Behavioral Intervention for Cancer Symptoms
Patients receiving treatment for advanced cancer often experience co-occuring pain, fatigue, and sleep disturbance that are not relieved with medications.
- Conditions
- Pain, Fatigue, Sleep Disturbance, Cancer
- Trial name
- NCT00946803
- Testing
- Patient-Controlled Cognitive-Behavioral Intervention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Wisconsin, Madison
Schizophrenia Disorders
Effect of AQW051 on Cognitive Function in Patients With Chronic Stable Schizophrenia
This PoC study is designed to assess the cognitive effects of doses of AQW051 in patients with chronic stable schizophrenia.
- Trial name
- NCT01163227
- Testing
- AQW051 2 mg (single and multiple doses), AQW051 15mg (single and multiple doses), AQW051 100mg (single dose), and 50mg (multiple doses)
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- Novartis Pharmaceuticals
Attention Deficit Hyperactivity Disorder (ADHD)
Organizational Skill Training (OST) in Schools
The primary aim of this project is to address the need for an effective school-based intervention for elementary school-aged students with Organization, Time Management, and Planning (OTMP) deficits by adapting an…
- Trial name
- NCT02663986
- Testing
- Organizational Skills Training (OST) Intervention
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- NYU Langone Health
Mental Health Wellness 1
Emotional Intelligence Program for Adolescents With Antisocial Behavior (DYNAMIS)
This study assessed the effectiveness of an emotional intelligence program based on the Salovey and Mayer model among adolescents exhibiting antisocial behavior.
- Trial name
- DYNAMIS (NCT06124183)
- Testing
- The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals
- Where
- Colombia
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Major Depression
Safety, Tolerability and Efficacy of the Transdermal System in Elderly Subjects With Major Depression
Objective of this 16-week, open-label study is to assess the safety and tolerability of once daily application of three doses of STS during continuous dosing in the treatment of elderly subjects with major depression.
- Trial name
- NCT00285766
- Testing
- Selegiline Transdermal System
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- Somerset Pharmaceuticals
Efficacy, Self, Fatigue; Muscle, Heart
Neuromodulation of the Autonomic Nervous System in Athletes
There are few studies in the literature that have evaluated the effects of using percutaneous stimulation of the auricular branch of the vagus nerve for sports purposes (to accelerate recovery after physical exertion).
- Conditions
- Efficacy, Self, Fatigue; Muscle, Heart, Fatigue, Mental, Fatigue; Combat
- Trial name
- NANSA (NCT06281795)
- Testing
- tVNS
- Where
- Russia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Bulimia Nervosa, Eating Disorder
Rapid Response to Day Hospital Treatment in Bulimia Nervosa and Purging Disorder
Treatments for bulimia nervosa (BN) have relatively high rates of nonremission and relapse, meaning that improving treatments is a high priority in this area.
- Trial name
- CBT-RR (NCT02444065)
- Testing
- Cognitive Behavior Therapy (CBT), Motivational Interviewing (MI)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Depression, Psychosis
Cognitive Remediation in Youth at Risk of Serious Mental Illness
The primary aim of the project is to test the effectiveness of a cognitive remediation treatment (CRT) program, My Brain Solutions (MBS), in addition to motivational interviewing (MI) in improving cognition and functional outcome…
- Conditions
- Depression, Psychosis, Anxiety, Mental Illness
- Trial name
- NCT02582528
- Testing
- Cognitive remediation treatment, Motivational Interviewing
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Bipolar Disorder
Neuropsychological Characterization of Patients With Bipolar Disorder and a History of Suicide Attempt
The main objective of this study is to evaluate decision-making using the Iowa Gambling Task (IGT) among patients with euthymic bipolar disorder according to their personal history of suicide attempt ("suicidal" vs.
- Trial name
- DECISIDAIRE (NCT02116400)
- Testing
- Interview, Neuropsychological testing, Serum concentration of lithium or sodium divalproate.
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Mammography, Early Diagnosis of Cancer
The Effect of Virtual Reality on Pain, Anxiety and Satisfaction Level Before Mammography
In this study, it is planned to determine the effect of virtual reality applied to women before mammography on pain, anxiety and satisfaction levels.
- Trial name
- NCT06265207
- Testing
- Virtual reality, routine maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ardahan University
Distress, Emotional
Universally Delivered Interventions for Young People
Mental health problems are amongst the major contributors to disease burden globally. According to a recent study, 34% of young people worldwide (aged 10-19) suffer from depression and more than half of this population belongs to…
- Trial name
- Mindset-PK (NCT06442007)
- Testing
- Behavioral Activation - single session intervention (BA-SSI), 4-session Mindset intervention
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Depressive Disorder, Depression
The Role of Inflammatory Processes in Development and Treatment of Depression
The study investigates the influence of inflammatory processes on the development and the course of uni- and bipolar depression.
- Conditions
- Depressive Disorder, Depression, Inflammation
- Trial name
- INFLAME-D (NCT03920475)
- Testing
- Sertraline or venlafaxine, Immune parameters
- Volunteers
- 104 people
- Sponsor
- Kliniken Essen-Mitte
Primary Biliary Cholangitis (PBC)
eMPower Mechanisms
Primary Biliary Cholangitis (PBC) is a chronic liver disease that can cause fatigue, itching, brain fog, and emotional distress, all of which can lower quality of life.
- Trial name
- NCT06861465
- Testing
- Online Mind-Body Wellness Program, Online Mind-Body Wellness Program + Nutritional Counselling
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Bipolar Affective Disorder, Schizophrenia Disorders
Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients
This observational study will characterise the general psychiatric and general medical phenotypes of 100 adults, sequentially admitted to NHS General Adult Psychiatry (GAP) "mental health" inpatient wards, providing the first…
- Conditions
- Bipolar Affective Disorder, Schizophrenia Disorders, Depression Disorders, Personality Disorders
- Trial name
- NCT07398365
- Testing
- Questionnaires, rating scales, & review of notes
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Nicotine Dependence, Alcohol Use
Pilot Study on Mindfulness for Tobacco and Alcohol in University Students
A. The study follows a randomized controlled design with approximately 60 smokers with a history of alcohol abuse age 18-29. The study will compare a 7-week mindfulness intervention to a matched 7-week education intervention to…
- Trial name
- NCT01679236
- Testing
- Mindfulness Training for Smokers, Interactive Learning for Smokers
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Wisconsin, Madison
ADHD
The Effects of an Online Mindfulness-based Intervention for Children with Attention-Deficit/Hyperactivity Disorder
This study will investigate the effects of an online mindfulness-based intervention with a randomized controlled trial.
- Trial name
- MindADHD (NCT06298136)
- Testing
- mindfulness-based intervention, child behavior management
- Where
- Hong Kong
- Volunteers
- 208 people
- Sponsor
- The Hong Kong Polytechnic University
ARMS, APS
Cognitive Behavioral Therapy for the Prevention of Paranoia in Adolescents at High Risk
The main objective of this study is to decrease the severity of symptoms and improve psycho-social functioning in youth at high risk of developing psychosis by providing a specialized Group-and-Family-based Cognitive Behavioral…
- Conditions
- ARMS, APS, Prodromal Symptoms
- Trial name
- NCT01923701
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Attention Deficit Disorder With Hyperactivity
Pharmacokinetic and Tolerability Study of NFC-1 in Subjects Aged 6-17 Years With ADHD
This is a open-label, single ascending dose, pharmacokinetic, and tolerability study of NFC-1 in Children and Adolescents (Ages 6-17 Years) with ADHD.
- Trial name
- NCT03006367
- Testing
- NFC-1 100 mg, NFC-1 200 mg, NFC-1 400 mg
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
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