Clinical trials: Mental and Behavioral Disorders
Osteoarthritis, Knee, Psychological Disorder
Total Knee Arthroplasty Combined With Psychological Intervention for Patients With Psychological Disorders
Objective To evaluate the incidence of psychological problems in total knee arthroplasty (TKA) patients and examine whether perioperative psychological intervention can improve the outcomes of and patient satisfaction with TKA.
- Conditions
- Osteoarthritis, Knee, Psychological Disorder, Psychological Intervention, Satisfaction
- Trial name
- NCT03715608
- Testing
- Psychological Intervention
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Obsessive-Compulsive Disorder
Precision Brain Mapping to Predict and Track Response to Exposure and Response Prevention Therapy in Youth With Obsessive-Compulsive Disorder
The goal of this clinical trial is to learn whether brain scan results can help predict and track changes in obsessive-compulsive disorder, or OCD, symptoms in children and teens ages 10 to 17 who receive Exposure and Response…
- Trial name
- NCT07570108
- Testing
- Exposure and Response Prevention Therapy, Clinical Assessments, Research MRI Sessions
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Combat Disorders, Stress Disorders, Post-Traumatic
A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD
The primary aim of this project is to examine whether administration of D-Cycloserine (DCS), a partial N-methyl-D-aspartate (NMDA) receptor agonist that has been shown to facilitate fear extinction, enhances the therapeutic…
- Trial name
- NCT00371176
- Testing
- Exposure therapy, D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- US Department of Veterans Affairs
Sleep Quality, Mood Disorders
Effect of the Nintendo Ring Fit Adventure Exergame on Running Completion Time
The coronavirus disease 2019 (COVID-19) outbreak has not only changed the lifestyles of people globally but has also resulted in other challenges, such as the requirement of self-isolation and distance learning.
- Trial name
- NCT05227040
- Testing
- Nintendo Ring Fit Adventure Exergame
- Where
- Taiwan
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Pain, Insomnia
Effect of Medical Marijuana on Neurocognition and Escalation of Use
This study will use a randomized controlled design to test whether patients who use medical marijuana, compared to a waitlist control group, experience a change in health outcomes (relief of symptoms, or adverse health outcomes…
- Conditions
- Pain, Insomnia, Depression, Anxiety
- Trial name
- MMNE (NCT03224468)
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mental Handicap
The Oral Accessibility Spatula (Spatule SAB)
The purpose of this study is to evaluate the efficiency and the safe use of a new medical device to improve the oral accessibility of disabled people during the oral-dental examination.
- Trial name
- SAB (NCT02818374)
- Testing
- oral accessibility spatula (SAB)
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Traumatic Brain Injury (TBI) Patients
Transcutaneous Vagus Nerve Stimulation for Attention and Memory
This clinical trial aims to evaluate whether transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive brain stimulation method, can improve attention and memory in veterans with traumatic brain injury (TBI) and…
- Trial name
- taVNS (NCT06723743)
- Testing
- Transcutaneous vagus nerve stimulation for attention in veterans with TBI, Soterix Medical Vagus Nerve Stimulation mini-CT
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Alzheimer Dementia (AD), Caregiver Burden of People With Dementia
VICA: A Virtual Care Assistant for Dementia Caregivers
This pilot randomized controlled trial evaluates the feasibility and preliminary efficacy of VICA, an AI-powered virtual care assistant that delivers evidence-based education, symptom monitoring, and coaching to informal…
- Trial name
- VICA (NCT07779785)
- Testing
- VICA - Virtual Informal Care Assistant, Education only BPSD mobile app
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Indiana University
Diabetes Mellitus, Type 2, Insomnia
The Impact of Cognitive Behavioral Therapy for Insomnia (CBT-I) on Glycemic Control in Older Type 2 Diabetes (T2D) Comorbid With Insomnia
This study is a RCT aiming to use CBT-I as intervention, compared to usual care as control, to elucidate the effect of CBT-I on glycemic control, sleep quality, psychological outcomes, and cognitive function in Hong Kong Chinese…
- Trial name
- NCT04831385
- Testing
- Cognitive Behavioural Therapy
- Where
- Hong Kong
- Volunteers
- 214 people
- Sponsor
- Chinese University of Hong Kong
Bereavement
Family-authored Digital ICU Diary Intervention to Support Bereaved Family Members in Intensive Care Unit: A Pilot Mixed Methods Study
Objectives: To assess the feasibility, acceptability and appropriateness of a family-authored digital ICU diary intervention for bereaved family members in Hong Kong ICUs, and to explore family members' experiences of writing…
- Trial name
- ICU-Diary-HK (NCT07788768)
- Testing
- Family-authored Digital ICU Diary Intervention, Standard Care
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Endometriosis
TENS Self-applied in the Complementary Treatment of Deep Endometriosis
Objective: to evaluate the effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) self-applied for the treatment of pain and the impact of this therapy on quality of life and sexuality of women with deep…
- Trial name
- tici_mira (NCT02769052)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
ADHD, Parenting
Moms Managing Attention-Deficit/Hyperactivity Disorder (ADHD) Study
The study will develop and test a behavioral program for pregnant individuals with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- MomMA (NCT06540547)
- Testing
- MomMA Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pittsburgh
Agitation, Psychosis
Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone
Behavioral and psychological symptoms of dementia (BPSD) are among the most distressing manifestations of dementia. Pharmacotherapy is frequently used and especially in institutional settings.
- Conditions
- Agitation, Psychosis, Alzheimer's Disease
- Trial name
- EscBPSD (NCT01119638)
- Testing
- Escitalopram, Risperidone
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Abarbanel Mental Health Center
Care Acceptor, Health, Pain, Postoperative
Effect of Comedy Therapy on Pain and Anxiety Levels After Ureterorenoscopy
The aim is to determine the effect of comedy therapy on pain and anxiety levels in patients after Uretero-Renoscopy (URS) surgery.
- Conditions
- Care Acceptor, Health, Pain, Postoperative, Anxiety Postoperative, Surgery
- Trial name
- NCT06805058
- Testing
- comedy therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bitlis Eren University
Attention Deficit Hyperactivity Disorder, Sleep Onset Insomnia
Comparing Treatment With Melatonin to Treatment With Stimulants (Methylphenidate) in Children With Attention Deficit Hyperactivity Disorder and Sleep Difficulties
The study hypothesis is that some children with Attention-Deficit-Hyperactivity-Disorder (ADHD) who also have sleep onset difficulties will improve with Melatonin treatment to an extent similar to that of stimulants treatment.
- Trial name
- NCT01393574
- Testing
- Melatonin, Methylphenidate
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Assaf-Harofeh Medical Center
Obsessive-Compulsive Disorder
Characterize The Modulatory Effects Of Dopamine D2/D3 Receptor Agonist And Antagonist Drugs On Compulsive Behaviors
3 groups of subjects (healthy controls, OCD subjects and stimulant-dependent subjects) will receive pramipexole (1.5 mg, single dose), amisulpride (400 mg, single dose) or placebo in a cross-over, double-blind, placebo-controlled…
- Trial name
- NCT00471588
- Testing
- Pramipexole, Amisulpride
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Depression, Anxiety
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT06261463
- Testing
- CAFES2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Illinois Chicago
Gambling Disorder, Gaming Disorder
GamReg Sweden - Quality Register for Gambling and Gaming Disorders
This is a quality register for the monitoring of clinical assessment and treatment for gambling disorder and gaming disorder in Swedish health care.
- Trial name
- NCT05276193
- Testing
- Observational health care register - no applicable intervention at present
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Region Skane
Adolescent Psychiatry, Antisocial Personality Disorders
Impaired Decision-making in Adolescents
There is clear evidence that aggressive behavior and disruptive behavior disorders (DBD) in middle childhood are associated with an increased risk for substance abuse in adolescence.
- Conditions
- Adolescent Psychiatry, Antisocial Personality Disorders, Substance-Related Disorders
- Trial name
- NCT01253993
- Where
- Netherlands
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Attention Deficit Hyperactivity Disorder
Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)
The purpose of this study is to evaluate the safety and efficacy of two medications--clonidine and methylphenidate--alone or in combination to treat attention deficit hyperactivity disorder in children ages 4 through 6.
- Trial name
- kiddie-CAT (NCT00414921)
- Testing
- clonidine, methylphenidate
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
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