Clinical trials: Mental and Behavioral Disorders
Substance Use Disorders
Feasibility of Music Therapy in Community Substance Misuse Treatment Services
Music Therapy (MT) has been shown to improve several symptoms experienced by people with Substance Use Disorder (SUD), such as depressive and anxiety symptoms, as well as negative emotions.
- Trial name
- CRAVEMT (NCT05180617)
- Testing
- Music Therapy
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Anglia Ruskin University
Schizophrenia, Schizoaffective Disorder
Recovery From Psychosis in Schizophrenia - The Impact of Cognitive-Behavioral Therapy
This study examines the impact of Cognitive-Behavior Therapy (CBT) on symptoms, physiological arousal, stressors, and the ways to deal with them in individuals with schizophrenia and related disorders.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT00791440
- Testing
- Cognitive-Behavior Therapy, Standard Psychiatric Treatment
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- New York State Psychiatric Institute
Depression, Unipolar, Depression, Bipolar
BioClock: Bright Light Therapy for Depressive Disorders
Bright Light Therapy (BLT) is a proven treatment for depression in seasonal and non-seasonal depressive disorders, as well as bipolar disorder.
- Trial name
- NCT05958940
- Testing
- Bright Light Therapy, Blue Light Blocking Glasses
- Where
- 2 sites in Netherlands
- Volunteers
- 231 people
- Sponsor
- Universiteit Leiden
Chronic Pain
Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain
Refractory chronic pain represents a serious and limiting health condition which does not respond to standard pharmacological therapy.
- Trial name
- NCT05099406
- Testing
- Transcranial electrical stimulation
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Santiago de Compostela
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Agitation, Dementia
Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)
A study to determine the safety and efficacy of BXCL501 dosing for episodes of agitation associated with dementia when they occur (given as needed [PRN]), for a maximum of 28 doses within a 12-week treatment period.
- Trial name
- NCT05271552
- Testing
- BXCL501
- Where
- 11 sites in United States
- Volunteers
- 151 people
- Sponsor
- BioXcel Therapeutics Inc
Dementia
Characteristics of Patients With Dementia Who Are Screaming in Nursing Homes
Patients with dementia develop behavioral problems over time. Among these, the investigators object screams or cries or disruptives vocalizations. Their cause is multifactorial and their management difficult in nursing homes.
- Trial name
- NCT04760015
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Heroin Dependence, Opioid Dependence
Biomarkers of Injectable Extended Release Naltrexone Treatment
This study evaluates the biological markers of treatment of opioid dependent individuals with an extended release formulation of the opioid antagonist naltrexone.
- Trial name
- NCT02324725
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pennsylvania
Nociceptive Pain, Pupillary Light Reflex Lost
Clinical Trial Using Pupillometry to Measure Nociception in Healthy Volunteers.
Pupillometry has been used in healthy volunteers to investigate the usefulness of the pupil light reflex as an indicator of pain intensity on pressure as a nociceptive stimulus.
- Conditions
- Nociceptive Pain, Pupillary Light Reflex Lost, Healthy, Pain, Procedural
- Trial name
- NCT04864340
- Testing
- CE marked medical device, Algometer, Comparator
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Thermoregulation, Sleep Disturbance
Acute Sleep Deprivation on Whole-body Heat Exchange During Exercise-heat Stress in Young and Older Men
Sleep deprivation has long been thought to modulate thermoregulatory function. Seminal work on sleep deprivation and thermoregulation has demonstrated that sleep-deprived individuals experience greater elevations in core…
- Conditions
- Thermoregulation, Sleep Disturbance, Heat Exchange, Aging
- Trial name
- NCT05838014
- Testing
- Sleep deprivation, Normal sleep
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
ADHD, Attention Deficit Hyperactivity Disorder
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
The purpose of the study is to examine the developmental trajectory of response control in boys and girls with ADHD entering adolescence.
- Trial name
- NCT05927506
- Testing
- Other
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Erectile Dysfunction
A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation
The primary purpose of the study is to demonstrate that dapoxetine can prolong intravaginal ejaculatory latency time (IELT) compared with placebo in men with premature ejaculation (PE).
- Trial name
- NCT00210704
- Testing
- Dapoxetine
- Volunteers
- 1,067 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
TBI, Anxiety
Cranial Electrotherapy Stimulation (CES) Therapy
The primary aim of this proposed study is to gather preliminary data for CES use in treating PTSD and anxiety symptoms in OEF/OIF Veterans with PTSD and a history of TBI.
- Conditions
- TBI, Anxiety, PTSD, Depression
- Trial name
- CES (NCT02453347)
- Testing
- CES Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Anxiety, Depression
Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies
This phase II trial tests the safety, side effects and how well group retreat psilocybin therapy works for the treatment of anxiety and depression in patients with solid tumors that have spread from where they first started…
- Conditions
- Anxiety, Depression, Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT07336238
- Testing
- Psychotherapy, Psilocybin, Survey Administration
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Sickle Cell Disease
Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease
Pediatric patients with sickle cell disease are at greater risk for exhibiting nocturnal enuresis (bedwetting) compared to the general population.
- Trial name
- NCT01959958
- Testing
- Questionnaire/Interview
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- St. Jude Children's Research Hospital
Secondary Traumatic Stress, Burnout, Professional
International Online Survey Assessing Secondary Traumatic Stress, Burnout, Compassion Satisfaction and Turnover Intentions Among Youth Care (Para)Professionals in Flanders, Wallonia, France and The Netherlands.
The goal of this observational study is to understand how work-related stress and personal characteristics affect the wellbeing of adults who work with children and young people in youth care services in Flanders, Wallonia…
- Conditions
- Secondary Traumatic Stress, Burnout, Professional, Compassion Fatigue, Compassion Satisfaction
- Trial name
- 2021_VUB_CFCSJ (NCT07384026)
- Where
- Belgium
- Volunteers
- 4,214 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders With Hyperactivity
An Open-label Study of NRP104 in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to assess the long-term safety and efficacy of three NRP104 doses of 30 mg, 50 mg, or 70 mg, administered at the same time daily, in the treatment of adults with ADHD.
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders With Hyperactivity, Attention Deficit Hyperactivity Disorders
- Trial name
- NCT00337285
- Testing
- Vyvanse (lisdexamfetamine dimesylate), NRP104
- Where
- 45 sites in United States
- Volunteers
- 349 people
- Sponsor
- New River Pharmaceuticals
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Stepped Care Treatment for Anxiety Resilience
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD.
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia
- Trial name
- STAR (NCT07228143)
- Testing
- Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Andrew Wiese
Gambling Disorder
Mindfulness-Based Cognitive-Behavioral Therapy for Gambling Disorder
To compare two group psychological interventions for Gambling Disorder in terms of effectiveness and efficacy. One group is based in cognitive-behavioral therapy (TAU) and the other group is based in TAU with Mindfulness-Based…
- Trial name
- NCT03497247
- Testing
- Mindfulness-Based Cognitive-Behavioral Therapy
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Breast Cancer, Gynecologic Cancer
Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms
RATIONALE: Dehydroepiandrosterone (DHEA) may help relieve vaginal symptoms in female cancer survivors. PURPOSE: This randomized phase III trial studies DHEA to see how well it works compared to placebo in treating postmenopausal…
- Trial name
- NCT01376349
- Testing
- prasterone
- Where
- 280 sites in United States
- Volunteers
- 464 people
- Sponsor
- Alliance for Clinical Trials in Oncology
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