Clinical trials: Mental and Behavioral Disorders
Attention Deficit Hyperactivity Disorder
Study of Computer Attention Training Programs in Schools for Children With Attention Deficit/Hyperactivity Disorder
This study examines the efficacy of two computer-based attention training systems, one with and one without neurofeedback. The training systems intend to help children learn to focus and attend more effectively.
- Trial name
- CATS (NCT01583829)
- Testing
- Neurofeedback, Cognitive Training, Waitlist Control
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Bipolar Disorder
Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania
Background: Bipolar disorder is one of the most common mental illnesses affecting 1%-4% of the population, and one of the leading causes of worldwide disability.
- Trial name
- NCT01893229
- Testing
- Lithium, Valproate, Oxcarbazepine
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Guiyun Xu
Attention Deficit Hyperactivity Disorder
Mindfulness Intervention for College Students With ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that commonly persists into adulthood and is associated with significant life impairments.
- Trial name
- NCT06076967
- Testing
- Mindfulness Awareness Practices for ADHD (adapted), Services-As-Usual
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama, Tuscaloosa
Caregiver Burden, Caregiver Burnout
Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.
The purpose of this study is to develop and test CarePair, a mobile application-based needs assessment and service referral platform for family caregivers of persons with dementia designed to alleviate stress and promote…
- Conditions
- Caregiver Burden, Caregiver Burnout, Dementia
- Trial name
- CarePair (NCT06418971)
- Testing
- CarePair
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cocaine Dependence
Brain Function and Structure in Cocaine Dependence
The purpose of this study is to examine the role of brain MRI findings in predicting treatment outcomes among individuals with cocaine dependence.
- Trial name
- NCT02080832
- Testing
- Citalopram
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Virginia Commonwealth University
Kinesiophobia, Metabolic Syndrome
Evaluation of Kinesophobia in Patients With Metabolic Syndrome
Metabolic syndrome (MS) is a public health problem characterized by central obesity, increased blood pressure and triglyceride levels, decreased blood HDL levels and the presence of insulin resistance (1).Kinesiophobia is a fear…
- Trial name
- NCT04123132
- Testing
- Kinesiophobia
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Psychiatric Disorders
TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric Patients
Mental disorders are often accompanied by health-risk behaviours, psychiatric comorbidity, and reduced functioning. TORCH investigates transdiagnostic mechanisms underlying multiple health behaviour change in adult psychiatric…
- Trial name
- TORCH (NCT07844798)
- Testing
- person-centred interventions
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Depression, Anxiety
Mental Health First Aid for College Students
Most college students with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Eating Disorders
- Trial name
- NCT02021344
- Testing
- Mental Health First Aid
- Where
- United States
- Volunteers
- 2,543 people
- Sponsor
- University of Michigan
Depression, Bipolar Disorder
Prevention of Mood Disorders by Folic Acid Supplementation
The purpose of this study is to determine whether daily folic acid supplements can prevent new episodes of mood disorder in young people (aged 14-24 years) of biological parents with current or past history of depression or…
- Trial name
- PRE-EMPT (NCT00459264)
- Testing
- Folic Acid
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Muscle Weakness, Late Effect of Burn
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
This study will measure efficacy of early in-patient exercise as an adjunct to current Standard of Care (SOC) for 96 patients in a multi-centre trial.
- Conditions
- Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
- Trial name
- MP-10 (NCT02739464)
- Testing
- Exercise + SOC PT/OT, SOC PT/OT
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Depressive Disorder
Safety and Efficacy Study in Patients With Major Depressive Disorder
The purpose of this study is to test if GSK163090 can reduce the symptoms of depression. The safety and how well the body can handle the drug will also be investigated.
- Trial name
- NCT00896363
- Testing
- GSK163090 1 mg, GSK163090 3 mg
- Where
- 15 sites in Russia
- Volunteers
- 99 people
- Sponsor
- GlaxoSmithKline
Pain, Postoperative, Orthognathic Surgery
Personalization of Opioid Prescription Following Orthognathic Surgery
This study aims to investigate pain management and satisfaction following orthognathic surgery, which is a type of surgery that corrects jaw and facial bone issues.
- Conditions
- Pain, Postoperative, Orthognathic Surgery, Opioid Use, Patient Satisfaction
- Trial name
- NCT05708521
- Testing
- Personalization of dose and frequency and instituting a tapering protocol of hydromorphone post-orthognathic surgery, Standardized dose and frequency of hydromorphone with no tapering post-orthognathic surgery
- Where
- Canada
- Volunteers
- 201 people
- Sponsor
- Nova Scotia Health Authority
Attention Deficit/Hyperactivity Disorder (ADHD)
The Efficacy and Safety of Phosphatidylserine-Omega3 in Children With Attention-Deficit/ Hyperactivity Disorder
The primary objective of this trial is to determine whether an oral administration of Phosphatidylserine-Omega3 would significantly improve the clinical symptoms of children suffering from ADHD.
- Trial name
- NCT00418184
- Testing
- Phosphatidylserine-Omega3, Colored cellulose tainted with fishy odor
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Enzymotec
Patient Compliance, Sleep Disorder
The Effects of Frequent Follow up on Compliance in Patients Receiving PAP Therapy Due to OSA (Pap: Positive Airway Pressure, OSA: Obstructive Sleep Apnea )
The investigators planned to investigate the effect of close monitoring on compliance and the factors affecting compliance among patients receiving PAP treatment due to OSA.This study was a single-center, prospective, randomized…
- Conditions
- Patient Compliance, Sleep Disorder, Obstructive Sleep Apnea of Adult
- Trial name
- NCT05894733
- Testing
- study group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital
ADHD
CTx-1301 Comparative Bioavailability Study
The primary purpose of this study is to compare the bioavailability of CTx-1301 (dexmethylphenidate) to the registered listed drug, Focalin XR and to evaluate dose proportionality of CTx-1301.
- Trial name
- NCT04138498
- Testing
- Dexmethylphenidate 5 Mg Oral Capsule, Extended Release, Dexmethylphenidate 6.25 mg Tablet, Dexmethylphenidate 40 Mg Oral Capsule, Extended Release
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Cingulate Therapeutics
Spinal Cord Injuries, Psychological Distress
A Guided Online ACT Intervention Combined With Psychoeducation for People With Spinal Cord Injury
The purpose of this preliminary study is to examine the effects of a guided online acceptance and commitment therapy (ACT) intervention combined with psychoeducation on people with spinal cord injury (SCI) who experience…
- Trial name
- NCT04670406
- Testing
- acceptance and commitment therapy (ACT) combined with psychoeducation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Substance-Related Disorders
Transcranial Direct Current Stimulation on Inhibitory Control in Addictions.
The research in neuroscience of the last 20 years is defined, in addition to continuing to advance in the field of behavioral and pharmacological therapy, by the birth and development of a new therapeutic category, called…
- Trial name
- NCT05350033
- Testing
- tDCS - tDCS
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad de Almeria
Colorectal Cancer (CRC)
Normobaric Oxygen Therapy in Colorectal Cancer Patients
Colorectal cancer (CRC) patients undergoing chemotherapy often experience anemia, oxidative stress, and immune suppression, significantly impacting their quality of life and treatment outcomes.
- Trial name
- NBO-ONCO (NCT06946004)
- Testing
- Normobaric oxygen therapy
- Where
- Poland
- Volunteers
- 254 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Depression, Postpartum
The Impact of Creative Interventions on Symptoms of Postnatal Depression (Cohort Study)
Post-natal depression (PND) is anticipated to affect 12.9% of new mothers with at least 75,000 cases per year in the UK alone. However, despite this, there is currently a worrying lack of support for new mothers, with data…
- Trial name
- NCT02526433
- Where
- United Kingdom
- Volunteers
- 2,558 people, healthy volunteers welcome
- Sponsor
- Royal College of Music
Binge Eating Disorder, Obesity
Craving, Binge Eating and Obesity
This research study is designed to look at the effectiveness of bupropion for reducing binge eating in overweight persons with binge eating problems.
- Trial name
- NCT00414167
- Testing
- bupropion
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Yale University
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