Clinical trials: Mesenteric Ischemia
Portal Vein Thrombosis, Mesenteric Vein Thrombosis
Treatment of Splanchnic Vein Thrombosis With Rivaroxaban. A Pilot, Prospective Cohort Study
Anticoagulant therapy is generally recommended for all patients presenting with acute symptomatic splanchnic vein thrombosis, starting with either low-molecular weight heparin (LMWH) or unfractionated heparin and continuing with…
- Conditions
- Portal Vein Thrombosis, Mesenteric Vein Thrombosis, Splenic Vein Thrombosis
- Trial name
- NCT02627053
- Testing
- rivaroxaban
- Where
- 4 sites in Canada, Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Small Bowel Gangrene, Mesenteric Artery Ischemia
Outcomes of Different Surgical Procedures After High Level Resection for Patients With Small Intestinal Gangrene
In this cohort study, aim to evaluate and compare short-term postoperative outcomes of different surgical procedures for patients with intestinal gangrene who underwent high level small bowel resection (< 150 cm from DJ).
- Conditions
- Small Bowel Gangrene, Mesenteric Artery Ischemia, Strangulated Hernia
- Trial name
- NCT06759727
- Volunteers
- 40 people
- Sponsor
- Assiut University
Ischemia, Fatty Acid-Binding Proteins
Kidney and Intestinal Markers for Early Detection of Organ Injury After Endovascular Aortic Repair
This study aims to investigate the predictive value of novel biomarkers and contrast-enhanced ultrasonography for early detection of abdominal end-organ (kidney and intestinum) hypoperfusion and ischemia in patients undergoing…
- Conditions
- Ischemia, Fatty Acid-Binding Proteins, Mesenteric Vascular Disease, Acute Kidney Injury
- Trial name
- KISMED (NCT01915446)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Regensburg
Mesenteric Ischemia, Permeability CT Technics
Dynamic Contrast Enhancement Computed Tomography Based Technic to Assess Gastro Intestinal Wall Perfusion : Feasibility Study
This feasibility study has therefore several aims: 1. construct a dedicated CT perfusion protocol for GIT wall perfusion; 2. used a two-compartment pharmacokinetic model which is more adapted that a unique compartment model; 3.
- Trial name
- PERFE-CT (NCT03367065)
- Testing
- Dynamic contrast enhanced computerised tomography
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Poitiers University Hospital
Laparotomy, Bowel Obstruction
Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery
The aim of this study is to investigate the effect of early, supplementary parenteral nutrition following emergency laparotomy. Currently, parenteral nutrition is used in postoperative patients if or when oral or enteral…
- Conditions
- Laparotomy, Bowel Obstruction, Ischemia, Mesenteric
- Trial name
- EATERS (NCT06089551)
- Testing
- SmofKabiven
- Where
- Denmark
- Volunteers
- 342 people
- Sponsor
- Copenhagen University Hospital at Herlev
Cardiac Arrest (CA)
Incidence of Colon Ischemia in Patients After Cardiopulmonary Resuscitation (CPR)
Bedside colonoscopy 24-36 hours after successful CPR
- Trial name
- NCT07359313
- Testing
- colonoscopy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Freiburg
Visceral Artery Aneurysm, Mesenteric Artery Ischemia
European Multicentre Study of Long-term Results Following Visceral Arteries Revascularization: the E-VisAR Study
Visceral arteries pathologies are a broad-spectrum of conditions with an extremely low incidence, estimated at 9.2% and 6.2% per 100,000 inhabitants for chronic and acute mesenteric ischemia, respectively, and 0.01-0.2% for…
- Conditions
- Visceral Artery Aneurysm, Mesenteric Artery Ischemia, Renal Artery Aneurysm, Renal Artery Stenosis
- Trial name
- E-VisAR (NCT06913530)
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Mesenteric Vascular Disease
Mesenteric Ischemia Markers Study
Vascular bowel disease remains a socially significant and potentially fatal condition (if it develops into AMI), primarily due to delayed diagnosis.
- Trial name
- MESMARK (NCT07460700)
- Testing
- Blood samples
- Where
- Belarus
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Belarusian State Medical University
Superior Mesenteric Artery Syndrome
SMAS: a Prospective Study in a Single Institution
Superior Mesenteric Artery Syndrome (SMAS) is a rare cause of duodenal obstruction, that should be suspected in cases of chronic, refractory upper digestive symptoms.
- Trial name
- NCT03416647
- Testing
- Duodenojejunostomy
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Azienda Ospedaliera di Padova
Non-Occlusive Mesenteric Ischaemia (NOMI), Acute Mesenteric Ischemia
Predictors of Transmural Non-Occlusive Mesenteric Ischemia in ICU Patients With Suspected Acute Mesenteric Ischemia
Acute mesenteric ischemia (AMI) is a rare but life-threatening condition associated with high mortality and major diagnostic challenges due to nonspecific clinical presentation and limited reliable biomarkers.
- Trial name
- AMESI-EST (NCT07610356)
- Testing
- Observation
- Where
- 2 sites in Estonia
- Volunteers
- 150 people
- Sponsor
- University of Tartu
Embolism Mesenteric
Preoperative Embolization of the Inferior Mesenteric Artery in Colorectal Surgery
Preoperative embolization of the inferior mesenteric artery in colorectal surgery (EPAMIR). This is a prospective, monocentric, non-randomized study.
- Trial name
- EPAMIR (NCT05422560)
- Testing
- Embolization of the inferior mesenteric artery
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Ischemia
Biomagnetic Characterization of Gastric Dysrhythmias:Study 2
The purpose of this study is to use the Squid magnetometer (Superconducting QUantum Interference Device) to help diagnose electrical and mechanical abnormalities of the stomach and intestines.
- Trial name
- SQUID (NCT00178984)
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Ultra-trail Participation
Evaluation of Biological Markers of Mesenteric Ischemia During an Ultra-trail
To assess the evolution of biological markers of mesenteric ischemia during ultratrail.
- Trial name
- ISKETRAIL (NCT03205098)
- Testing
- Blood analysis
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Mesenteric Artery Ischemia, Thromboembolism
Endovascular thromBectomy of Acute Mesentery Vessels Occlusion Hybrid With Emergent Laparoscopic Surgery
Acute mesenteric artery thromboembolism(AMT) is one of the important causes of acute abdomen and intestinal necrosis. If the intestinal blood supply is not restore in time, the prognosis of the disease is often poor and even…
- Trial name
- BOWEL (NCT04686981)
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Non-Occlusive Mesenteric Ischemia
Demographics, Diagnosis, Management, and Outcomes of Non-occlusive Mesenteric Ischemia.
This prospective multicenter observational study, conducted between June , 2022, and April, 2023, is a preplanned analysis of the AMESI study titled 'Demographics, diagnosis, management, and outcomes of non-occlusive mesenteric…
- Trial name
- NCT06970015
- Testing
- No intervention
- Where
- Estonia
- Volunteers
- 566 people
- Sponsor
- University of Tartu
Bowel; Ischemic, Acute
FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery
This is a prospective, multicentre, non-randomized cohort study using real-time intraoperative visualization of bowel perfusion by indocyanine green (ICG) in all-cause bowel ischemia.
- Trial name
- FLAMES (NCT06322862)
- Testing
- Indocyanine green
- Where
- 5 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer, Rectal
Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum
The present study will investigate the safety of inferior mesenteric artery embolization prior to rectal surgery, according to IDEAL recommendations (Lancet 2009).
- Trial name
- AMIREMBOL_2 (NCT06236633)
- Testing
- Ischemic preconditioning, Arteriogram
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Mesenteric Ischemia
Investigation of Chronic Intestinal Ischemia
Patients suspected of chronic mesenteric ischemia caused by atherosclerosis or median arcuate ligament syndrome shall be investigated with trans mucosal and transserosal laser Doppler flowmeter and visible light spectroscopy.
- Trial name
- NCT02914912
- Where
- 2 sites in Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Acute Mesenteric Ischemia, Sepsis Bacterial
Performance of the SeptiCyte LAB Test for Antibiotic Stewardship in Mesenteric Ischemia
This study will help determine whether the SeptiCyte LAB test can accurately differentiate between SIRS and actual infections in postoperative patients, potentially reducing unnecessary antibiotic use and improving patient…
- Conditions
- Acute Mesenteric Ischemia, Sepsis Bacterial, Intra-abdominal Infection, Digestive Inflammation
- Trial name
- SPASM (NCT06507423)
- Testing
- Septicyte Lab Test pre operative, Septicyte Lab Test post operative
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Mesenteric Ischemia
Promoting Early Diagnosis of Chronic Mesenteric Ischemia
CMI is an incapacitating disease and timely diagnosis remains problematic. Despite the substantial compensatory capacity of the mesenteric circulation CMI is relatively common, its incidence being comparable to other well-known…
- Trial name
- PROMISE (NCT05735002)
- Testing
- 13C-butyrate breath test
- Where
- 4 sites in Netherlands
- Volunteers
- 296 people
- Sponsor
- Erasmus Medical Center