Clinical trials: Mesenteric Ischemia, open to volunteers
Chronic Mesenteric Ischemia
Promoting Early Diagnosis of Chronic Mesenteric Ischemia
CMI is an incapacitating disease and timely diagnosis remains problematic. Despite the substantial compensatory capacity of the mesenteric circulation CMI is relatively common, its incidence being comparable to other well-known…
- Trial name
- PROMISE (NCT05735002)
- Testing
- 13C-butyrate breath test
- Where
- 4 sites in Netherlands
- Volunteers
- 296 people
- Sponsor
- Erasmus Medical Center
Cardiac Arrest (CA)
Incidence of Colon Ischemia in Patients After Cardiopulmonary Resuscitation (CPR)
Bedside colonoscopy 24-36 hours after successful CPR
- Trial name
- NCT07359313
- Testing
- colonoscopy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Freiburg
Small Bowel Gangrene, Mesenteric Artery Ischemia
Outcomes of Different Surgical Procedures After High Level Resection for Patients With Small Intestinal Gangrene
In this cohort study, aim to evaluate and compare short-term postoperative outcomes of different surgical procedures for patients with intestinal gangrene who underwent high level small bowel resection (< 150 cm from DJ).
- Conditions
- Small Bowel Gangrene, Mesenteric Artery Ischemia, Strangulated Hernia
- Trial name
- NCT06759727
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cancer, Rectal
Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum
The present study will investigate the safety of inferior mesenteric artery embolization prior to rectal surgery, according to IDEAL recommendations (Lancet 2009).
- Trial name
- AMIREMBOL_2 (NCT06236633)
- Testing
- Ischemic preconditioning, Arteriogram
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Mesenteric Ischemia
ORal Antibiotics in Acute Mesenteric Ischemia
Acute mesenteric ischemia (AMI) is a life-threatening condition with an increasing incidence (7-13/100000 PY). The mortality of AMI is associated with the development and extent of transmural intestinal necrosis (IN), ranging…
- Trial name
- ORIAMI (NCT06387147)
- Testing
- Gentamicin, Metronidazole
- Where
- 4 sites in France
- Volunteers
- 196 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Superior Mesenteric Artery Syndrome
Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population
Multicenter, prospective, observational research project on children aged from 10 to 15 years old undergoing abdominal ultrasound examinations during routine clinical practice.
- Trial name
- NCT04515251
- Testing
- Ultrasound measurements
- Where
- 2 sites in Switzerland
- Volunteers
- 289 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Non-Occlusive Mesenteric Ischaemia (NOMI), Acute Mesenteric Ischemia
Predictors of Transmural Non-Occlusive Mesenteric Ischemia in ICU Patients With Suspected Acute Mesenteric Ischemia
Acute mesenteric ischemia (AMI) is a rare but life-threatening condition associated with high mortality and major diagnostic challenges due to nonspecific clinical presentation and limited reliable biomarkers.
- Trial name
- AMESI-EST (NCT07610356)
- Testing
- Observation
- Where
- 2 sites in Estonia
- Volunteers
- 150 people
- Sponsor
- University of Tartu
Bowel; Ischemic, Acute
FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery
This is a prospective, multicentre, non-randomized cohort study using real-time intraoperative visualization of bowel perfusion by indocyanine green (ICG) in all-cause bowel ischemia.
- Trial name
- FLAMES (NCT06322862)
- Testing
- Indocyanine green
- Where
- 5 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Mesenteric Ischemia
Blood Flow and Oxygenation in the Portal Vein in Subjects With Chronic Narrowing of the Blood Vessels to the Gut
In this study the investigators will, with an Magnetic Resonance Imaging (MRI) method, measure the oxygen content in the portal vein, which conduct the blood from the guts to the liver.
- Trial name
- NCT07182669
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Mesenteric Ischemia
Evaluation of the Discriminative Abilities of Biomarkers for the Diagnosis of Acute Mesenteric Ischemia Compared With Another Similar Clinical Presentation: a Pilot Study
Acute mesenteric ischemia (AMI) is associated with high mortality (50-80%). The prognosis depends on the time it takes to diagnose the condition, and the possibility of revascularization in eligible patients.
- Trial name
- SOS-ISMES (NCT06869564)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Mesenteric Vascular Disease
Mesenteric Ischemia Markers Study
Vascular bowel disease remains a socially significant and potentially fatal condition (if it develops into AMI), primarily due to delayed diagnosis.
- Trial name
- MESMARK (NCT07460700)
- Testing
- Blood samples
- Where
- Belarus
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Belarusian State Medical University
Visceral Artery Aneurysm, Mesenteric Artery Ischemia
European Multicentre Study of Long-term Results Following Visceral Arteries Revascularization: the E-VisAR Study
Visceral arteries pathologies are a broad-spectrum of conditions with an extremely low incidence, estimated at 9.2% and 6.2% per 100,000 inhabitants for chronic and acute mesenteric ischemia, respectively, and 0.01-0.2% for…
- Conditions
- Visceral Artery Aneurysm, Mesenteric Artery Ischemia, Renal Artery Aneurysm, Renal Artery Stenosis
- Trial name
- E-VisAR (NCT06913530)
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Acute Mesenteric Ischemia
Searching Biomarkers of Acute Intestinal Ischemic Injuries
The aim of the SURVIBIO study is to characterize accurate biomarkers for acute mesenteric ischemia, in particular at early stages.
- Trial name
- Survibio (NCT03518099)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 556 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mesenteric Ischemia
Cohort SURVI : Intestinal Ischemia and Vascular Diseases
The first Intestinal Vascular Emergency Unit (SURVI), with the institutional support of AP-HP, opened on 4 January 2016, within the Paris-Nord Val de Seine University Hospital Group.
- Trial name
- Survibase (NCT04746534)
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mesenteric Ischemia, Bowel; Ischemic
Copenhagen Mesenteric Stent Study - A Randomized Trial of Stent Versus Covered Stent Treatment for Chronic Mesenteric Ischemia
Chronic mesenteric ischemia (CMI) is often caused by narrowings in the arteries providing blood to the intestines. Endovascular stent placement is considered the preferred treatment for this condition.
- Conditions
- Mesenteric Ischemia, Bowel; Ischemic, Superior Mesenteric Atherosclerosis, Mesenteric Artery Stenosis
- Trial name
- COMESS (NCT05244629)
- Testing
- BMS vs. CS
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Mesenteric Ischemia
Assessment of Quality of Life After Acute Mesenteric Ischemia
Acute mesenteric ischemia is a severe abdominal emergency associated with a poor prognosis. While numerous studies have been conducted on the incidence, outcomes, and risk factors of mesenteric ischemia, very few focus on the…
- Trial name
- EQVIMA-1 (NCT07303153)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Mesenteric Ischemia, Median Arcuate Ligament Syndrome
Intestinal Ischemia Biomarker in Patients With Chronic Mesenteric Ischemia
Plasma Alpha glutathione S transferase (Alpha GST) has been previously demonstrated to be raised in patients with chronic mesenteric ischemia (CMI) caused by atherosclerosis and in patients with median arcuate ligament syndrome…
- Conditions
- Chronic Mesenteric Ischemia, Median Arcuate Ligament Syndrome, Crohn Disease, Cholelithiasis
- Trial name
- NCT06468774
- Testing
- Laparoscopic surgery
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Gastric Outlet Obstruction, Small Bowel Obstruction
GT Metabolic Magnet System in Adults With Gastrointestinal Disorders
Evaluate the performance and safety of the GT Metabolic Magnet System for the creation of side-to-side compression anastomosis in the stomach and/or small bowel in conditions requiring an anastomosis as part of the underlying…
- Conditions
- Gastric Outlet Obstruction, Small Bowel Obstruction, Superior Mesenteric Artery Syndrome
- Trial name
- NCT07317076
- Testing
- Magnet System
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- GT Metabolic Solutions, Inc.
Mesenteric Ischemia, Median Arcuate Ligament Syndrome
Coeliac Artery Release or Sham Operation
In patients with Median Arcuate Ligament Syndrome (MALS), significant external compression of the coeliac artery (CA) by the median arcuate ligament (MAL) increasing mucosal ischemia (1,2) is assumed to cause chronic disabling…
- Conditions
- Mesenteric Ischemia, Median Arcuate Ligament Syndrome, Dunbar Syndrome, Coeliac Artery Compression
- Trial name
- CARoSO (NCT05468580)
- Testing
- Endoscopic Coeliac Artery Release (eCAR)
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Medisch Spectrum Twente
Chronic Mesenteric Ischemia, Ischemia, Mesenteric
Translesional PRESSURE Measurements to Assess Clinical Relevance of a Mesenteric Artery Stenosis (PRESSURE-study)
Chronic mesenteric ischemia (CMI) is an incapacitating disease with a vast impact on quality of life due to severe abdominal pain after a meal, resulting in fear of eating and subsequent weight loss.
- Trial name
- PRESSURE (NCT07059520)
- Where
- 3 sites in Netherlands
- Volunteers
- 125 people
- Sponsor
- Erasmus Medical Center