Clinical trials: Metabolic Cardiovascular Syndrome
Pre Diabetes, Impaired Glucose Tolerance
Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control
This 12 week placebo-controlled study evaluates the efficacy and safety of E. hallii supplementation.
- Conditions
- Pre Diabetes, Impaired Glucose Tolerance, Insulin Sensitivity, Insulin Resistance
- Trial name
- NCT04529473
- Testing
- Eubacterium hallii
- Where
- 3 sites in United States, Ireland and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Prevention
Health Effects of Commuter Cycling
The purpose of this study is to determine whether cycling to school is effective in the prevention of the metabolic syndrome.
- Trial name
- NCT01236222
- Testing
- Cycling to school
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Obesity, Chronic Kidney Disease
FFT, Inflammation, Lipid Metabolism, Blood Pressure and Organ Damage in Patients With Obesity, Chronic Kidney Disease (CKD).
Fructose intake from added sugars has increased dramatically over the last century and has recently been implicated as potential contributor to metabolic syndrome, obesity, hypertension, inflammation and kidney disease.
- Conditions
- Obesity, Chronic Kidney Disease, Metabolic Syndrome
- Trial name
- NCT01332526
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Collegium Medicum w Bydgoszczy
Systolic and Diastolic Blood Pressure Levels, Uric Acid Levels
Hyperuricemia on Hypertension and Metabolic Syndrome
The purpose of this study is to evaluate the influence of hyperuricemia treatment compared with placebo on participants with high risk of hypertension and metabolic syndrome.
- Conditions
- Systolic and Diastolic Blood Pressure Levels, Uric Acid Levels, Metabolic Syndrome Parameters, Hepatic Enzymes
- Trial name
- NCT01157936
- Testing
- Allopurinol
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Anorexia Nervosa, Metabolic Syndrome
Does Metabolic Syndrome Exist in Anorexia Nervosa?
The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of…
- Trial name
- NCT00271921
- Testing
- Calorie controlled diet
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Prediabetes, Hyperglycemia
Personality Traits and Biochemical Risk Phenotypes
This prospective observational study investigates the association between personality traits and routine laboratory abnormalities in adults undergoing routine health assessment.
- Conditions
- Prediabetes, Hyperglycemia, Metabolic Syndrome
- Trial name
- PHEBiP (NCT07653048)
- Where
- Romania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical Center TOPMED
Metabolic Syndrome as Breast Cancer Risk Factor
Metabolic Syndrome as Modifiable Risk Factor for Breast Cancer
Healthy women and women with breast cancer have been enrolled in our nested case-control study between 2008 and 2009 in order to evaluate the association between metabolic syndrome and breast cancer, analyzing anthropometric…
- Trial name
- NCT01172886
- Where
- Italy
- Volunteers
- 777 people, healthy volunteers welcome
- Sponsor
- Sbarro Health Research Organization
Metabolic Syndrome
Egg Yolk and Underlying Metabolisms on Modifying HDL Levels in Individuals With Metabolic Syndrome
This research compare the effects of low carbohydrate intake and consumption of 3 eggs per day, and low energy diet on diabetes control and biomarkers of CVD in obese people.
- Trial name
- NCT04608136
- Testing
- Diet intervention
- Where
- Thailand
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cardiometabolic Syndrome
The Platform for Interdisciplinary Cardiovascular-metabolic-neurovascular Diseases (PICMAN)
Background Changes in metabolism and mitochondrial function appear to precede cardiac dysfunction, with much evidence supporting metabolic dysregulation as one of the earliest precursors of cardiovascular disease.
- Trial name
- PICMAN (NCT06062836)
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Nonalcoholic Steatohepatitis, Metabolic Syndrome
The Role of Leptin Receptors in NASH
NAFLD is a spectrum of liver diseases associated with varying degrees of hepatic steatosis, inflammation, and in some cases, fibrosis.
- Trial name
- NASH (NCT00583999)
- Testing
- no interventions, only regular blood-draw
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Metabolic Syndrome
IT-Based Training in Metabolic Syndrome
Prospective, randomized, single center, controlled intervention study to investigate the effect of a systematic combined personal and IT-based training on the outcome of patients with metabolic syndrome.
- Trial name
- SPRINT (NCT00686244)
- Testing
- Combined 3-monthly endurance and strength training
- Where
- Germany
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Metabolic Syndrome, Obesity
Effects of Alpha Lipoic Acid Supplementation on Metabolic Syndrome Markers in Young Overweight or Obese Males
Eight weeks supplementation of alpha lipoic acid (known superantioxidant already produced by the body) will significantly improve metabolic syndrome markers (e.g., excess body weight, blood pressure, glucose, insulin, blood…
- Trial name
- ALA (NCT03342599)
- Testing
- Alpha Lipoic Acid Supplement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of La Verne
HIV Infections, Dyslipidemias
Seronegatives and Metabolic Abnormalities Protocol 2 (SAMA002): Study to Compare the Effect of Kaletra and Combivir® in HIV-Negative Healthy Subjects
This is a randomised study of the effect of treatment with Combivir (zidovudine [AZT] and lamivudine [3TC]) and Kaletra (lopinavir [LPVr]), alone and in combination, on the development of abnormalities in lipid and glucose…
- Conditions
- HIV Infections, Dyslipidemias, Glucose Metabolism Disorders, Metabolic Diseases
- Trial name
- NCT00192621
- Testing
- Combivir (zidovudine [AZT] / lamivudine [3TC]), Kaletra (lopinavir [LPVr])
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Glucose Intolerance, Type 2 Diabetes Mellitus
Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
The purpose of the randomized trial is to quantify the effect of vitamin D and calcium supplementation on beta-cell function, insulin sensitivity, glucose tolerance and systemic inflammation and other cardiometabolic outcomes in…
- Conditions
- Glucose Intolerance, Type 2 Diabetes Mellitus, Metabolic Syndrome
- Trial name
- CaDDM (NCT00436475)
- Testing
- Vitamin D3 2,000 IU orally once daily, Calcium Carbonate 400 mg orally twice daily
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Metabolic Syndrome
Metabolic Syndrome and Insulin Resistance at Allina
Vitamin D deficiency is widespread and appears to represent one easily and inexpensively modifiable risk factor for diabetes and cardiovascular disease.
- Trial name
- MISURA (NCT01545830)
- Testing
- vitamin D3 (cholecalciferol)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Obesity, Childhood, Cardiovascular Diseases
Paediatric Obesity and Cardiovascular Dysfunction
Background Childhood obesity has been related to an impaired cardiovascular structure and function. Aims of this study will be to evaluate early cardiovascular abnormalities in a large population of obese children and adolescents…
- Trial name
- NCT03169257
- Testing
- diet plus physical activity
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Cardiometabolic Syndrome
Effects of Quercetin on Cardiometabolic Outcomes
Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount.
- Trial name
- NCT06230861
- Testing
- Quercetin
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Pancreatic Ductal Adenocarcinoma, Pancreatic Cyst
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
The long-term goal of our PIC is to develop effective strategies that can be applied clinically at the point-of-care to prevent, intercept, or detect PDAC at an early stage, thereby reducing PDAC burden and saving lives.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatic Cyst, Chronic Pancreatitis, Fatty Pancreas
- Trial name
- NCT05692596
- Testing
- Data collection
- Where
- United States
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Polycystic Ovary Syndrome
Could the Therapy With Inositol Affect the Cardiovascular Risk in PCOS Women? Results of a Randomized Clinical Trial
Polycystic ovary syndrome (PCOS) is associated with an increased cardiovascular risk. The aim of the study was to evaluate long-term effects of inositol on some cardiovascular risk factors in PCOS patients.
- Trial name
- NCT01574261
- Testing
- Inositol
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
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