Clinical trials: Metabolic Control
Type 2 Diabetes Mellitus, Diabetic Kidney Disease
Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.
Current study will render insight in to the role of renal hypoxia in the diabetic kidney and is able to associate its finding with measurements of renal perfusion and glomerular filtration rate.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Diabetic Nephropathy, Renal Hypoxia
- Trial name
- ROCKIES (NCT04027530)
- Testing
- Ertugliflozin 15 mg
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Obesity, Eating Disorders
Internet Weight Control for Bingeing Adolescents
The purpose of this study is to determine if an internet-based intervention designed to reduce binge eating and improve healthy weight regulation skills will result in reductions in binge eating and weight loss, or weight…
- Trial name
- NCT00125112
- Testing
- Internet-based intervention designed to reduce binge eating and improve healthy weight regulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Iron Deficiency, Anaemia in Children
A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of…
- Trial name
- IHAT-Gut (NCT02941081)
- Testing
- IHAT, Ferrous Sulphate
- Where
- The Gambia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Type 2 Diabetes, Glycemic Control
Blood Glucose Homeostasis in Type 2 Diabetes: the Effects of Saccharose
Hyperglycemia forms a direct and independent risk factor for the development of cardiovascular co-morbidities in type 2 diabetes.
- Trial name
- NCT00821665
- Testing
- Sucrose consumption, water consumption
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Osteoporosis, Cardiovascular Disease
Epimedium Prenylflavonoid (EP) Extract for Osteoporosis and Cardiovascular Disease
The primary objective of the trial is to develop Epimedium Prenylflavonoid (EP) extract as a pharmaceutical-quality intervention for post-menopausal osteoporosis and cardiovascular disease.
- Trial name
- NCT02931305
- Testing
- Epimedium Prenylflavonoids Extract
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Type 2 Diabetes, Obesity
Changes in Incretins Response and Glycemic Control After Gastric Bypass Surgery in Type 2 Diabetic Patients Versus Healthy
The purpose of this study is to determine the early changes in gut hormonal, and other metabolites with known relations to the glycemic homeostasis.
- Trial name
- NCT01820273
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Obesity, Eating Behaviour
The Effect of Neurofeedback on Eating Behaviour
Neuroimaging is becoming increasingly common to investigate the neural networks underlying eating behaviour and food preference in normal-weight and obese humans.
- Trial name
- NCT02148770
- Testing
- Neurofeedback
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Cholesterol; Lipidosis
Can Mindful Eating Improve Cholesterol and Glucose Level
This study aims to explore the effectiveness of mindful eating and its effect on cholesterol and glucose level. The participants will be required to get tested for their fasting total cholesterol and blood glucose level for two…
- Trial name
- NCT04833595
- Testing
- Mindfulness practice
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
High Blood Glucose
Brown Seaweeds Effect on Glucose Tolerance and Appetite Response
The project is a randomized, 3-way, blinded crossover trial in which 20 healthy, fasted participants consume meals with 30 g of a linear corn starch and 5 g of one of the seaweeds, Laminara digitata or Undaria pinnatifida or a…
- Trial name
- NCT02608372
- Testing
- LD, UP, CTR
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Overweight and Obesity
Total Lifestyle Reconstruction for Body Weight Control and Maintenance
Obesity stands as a significant health concern of the 21st century. The prevalence of obesity is steadily rising worldwide, and Taiwan is no exception, with nearly four to five out of ten individuals facing issues of overweight…
- Trial name
- NCT06223386
- Testing
- Designed on-line course A with 3-month consultation with the dietitian, Designed on-line course B with 3-month consultation with the dietitian, Designed on-line course B with 3-month consultation with the dietitians + 3-month daily dietary assessment by the dietitians
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Academia Sinica, Taiwan
Metformin, Prediabetes
Effect of Metformin on Healthy Live Birth in Women With Prediabetes
To evaluate the efficacy and safety of metformin pretreatment on reproductive outcomes in infertile women with prediabetes.
- Conditions
- Metformin, Prediabetes, In-Vitro Fertilization
- Trial name
- MELT-PreDM (NCT06064669)
- Testing
- Metformin pretreatment before ovarian stimulation, Metformin pretreatment before endometrial preparation for frozen embryo transfer
- Where
- China
- Volunteers
- 988 people, healthy volunteers welcome
- Sponsor
- Shandong University
Diabetes Mellitus, Type 2
Smartphone Application for Type 2 Diabetes
Since diabetes is a chronic disease closely related to unhealthy lifestyle, the improvement and management of living habits are as significant as medical care with regard to the disease.
- Trial name
- NCT03468283
- Testing
- mobile application for diabetes
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kangbuk Samsung Hospital
Obesity
The Addition of Probiotic Consumption to a Nutritional Intervention and Caloric Restriction on Body Weight and Composition in Overweight Participants
Limited interventional human studies suggest that probiotic supplementation may be a beneficial strategy for promoting weight loss when added to a nutritional intervention via their effects on lipid absorption and metabolic…
- Trial name
- NCT02962583
- Testing
- Weight loss, Probiotic Formula
- Where
- Canada
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Laval University
Glucose Intolerance, Microbial Colonization
Effects of Tagatose on Glycemic Response and Gastrointestinal Microbiota in Healthy Adults
The primary objective of this clinical-trial is to determine, in subjects with impaired fasting glucose (IFG) and/or insulin resistance (IR), if tagatose meets the definition of a prebiotic, namely that consuming tagatose for 4…
- Trial name
- NCT06920641
- Testing
- Tagatose
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Medical Education, Endocrine System Diseases
Integrated PBL-CBL-CTTM Teaching to Enhance Clinical Self-Efficacy in Endocrine Critical Illness Among Internal Medicine Residents: An RCT
This randomized controlled trial evaluates whether an integrated online-offline multimodal teaching approach combining Problem-Based Learning (PBL), Case-Based Learning (CBL), and Case Three-Dimensional Teaching Method (CTTM)…
- Conditions
- Medical Education, Endocrine System Diseases, Critical Illness
- Trial name
- PBL-CBL-CTTM (NCT07801170)
- Testing
- Lecture-based learning (LBL), PBL plus LBL, Integrated PBL-CBL-CTTM
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chaohu Hospital of Anhui Medical University
Bone Loss, Osteoporosis
Single Ascending-Dose Study to Characterize the Safety, Pharmacokinetics, and Pharmacodynamics of CEP-37251 in Healthy Postmenopausal Women
Study to Characterize the Safety, Pharmacokinetics, and Pharmacodynamics of CEP-37251 in Healthy Postmenopausal Women.
- Trial name
- NCT01159873
- Testing
- CEP-37251
- Where
- Australia
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cephalon
Malnutrition
Randomized Controlled Trial in South Africa Comparing the Efficacy of Complementary Food Products on Child Growth
Complementary food supplements (CFS), fortified products that are mixed with the infant's usual complementary foods, have the potential to improve nutrition among infants.
- Trial name
- TSWAKA (NCT01845610)
- Testing
- Fortified fat-based paste with essential fatty acids, DHA, ARA, phytase, L-lysine, potassium, phosphorous, magnesium and manganese, Fortified fat-based paste with essential fatty acids
- Where
- South Africa
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Disorder of Circulatory System, Metabolic Disease
Investigation of Long-term Effects of CarelessTM on Microcirculation
Aim of the study is to investigate long-term effects of CarelessTM, a Mangifera indica fruit powder on microcirculation and endothelial function after supplementation of 4 weeks.
- Trial name
- NCT02588313
- Testing
- Mango fruit powder
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vital Solutions Swiss AG
Contraception
Metabolism Study to Investigate the Impact of a Sequential Oral Contraceptive
The purpose of this study is to confirm the safety of SH T00658ID with regard to plasma lipids, hemostatic variables, and carbohydrate metabolism.
- Trial name
- NCT00185224
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), SH D00264A (Triquilar)
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bayer
Type 2 Diabetes Mellitus
Safety Study to Evaluate BMS-767778 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus (T2DM)
To assess the safety and tolerability and the PK/PD relationship of BMS-767778 administered as single and multiple oral doses in healthy subjects, and in subjects with T2DM
- Trial name
- NCT00707590
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
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