Clinical trials: Metabolic Control
Hyperglycemia
Gycabiane and Glycemic Control of Prediabetic Subjects
The purpose of this study is to examine the effects of supplementation Glycabiane, a dietary supplement, on glycemic control of overweight prediabetic subjects.
- Trial name
- NCT01530685
- Testing
- Glycabiane
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- PiLeJe
Diabetes Type 2, Malnutrition
Evaluation of Glycemic Control by Flash Monitoring of Glucose (MFG) in Malnourished Patients With Type 2 Diabetes
Evaluation of Glycemic Control by Flash Monitoring of Glucose (MFG) in Malnourished Patients With Type 2 Diabetes (MFG SNO)
- Trial name
- MFG-SNO (NCT05443204)
- Testing
- Fortimel energy, Nutrision Advanced Diason Energy HP
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Type 2 Diabetes
Sitagliptin in Prevention of Type 2 Diabetes Mellitus
The hypothesis is, in subjects with persistent impaired glucose tolerance(IGT) , sitagliptin will decrease the conversion rate to diabetes as compared to a placebo in three years.
- Trial name
- SITAGLIPTIN (NCT01038648)
- Testing
- Sitagliptin, life style modification at base line
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
Vitamin D Deficiency
A Study to Assess the Effectiveness of an Investigational Drug in Elderly Subjects With Low Vitamin D Levels (0822A-009)
This study will assess the effectiveness of an investigational drug in elderly subjects with low vitamin D levels.
- Trial name
- NCT00242476
- Testing
- MK0822A
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Hypercholesterolemia
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.
AZD8233 has not been evaluated in clinical studies previously. This is a first-in-human (FiH) study. This study will assess the safety, tolerability and pharmacokinetics (PK) of AZD8233, following subcutaneous (SC) administration…
- Trial name
- NCT03593785
- Testing
- AZD8233
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Parkinson's Disease, Gaucher's Disease
Intravenous N-acetylcysteine for the Treatment of Gaucher's Disease and Parkinson's Disease
The investigators are interested in determining if the investigators are able to detect changes in brain chemistry using Magnetic Resonance Spectroscopy (MRS) in individuals with Parkinson's disease (PD), those with Gaucher's…
- Trial name
- NCT01427517
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Osteopenia of Prematurity
Comparison of Two Different Doses of Vitamin D in Preterm Infants
randomized clinical trial comparing two different doses of vitamin d supplementation in preterm infants
- Trial name
- NCT03889717
- Testing
- vitamin D
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes
A Computer-Based Simulation of DKA Management
A 2-by-2 factorial cluster randomized controlled trial was performed to: 1) Compare the effects of supervised (coached) versus unsupervised (no coach) administration of the DKA simulator on trainees' knowledge of DKA management…
- Trial name
- DKA (NCT02799563)
- Testing
- Coach, Preselected number of cases, Coach, Self-selected number of cases, No coach, Preselected number of cases
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Gastric Emptying, Diabetes Mellitus
The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.
The purpose of this study is to determine whether 3 g cinnamon was sufficient to delay the gastric emptying rate of a high-fat solid meal and subsequently reduce postprandial blood glucose and lipid responses, oxidative stress…
- Trial name
- CinnGastEmpt (NCT01350284)
- Testing
- Cinnamon
- Where
- Ireland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Insulin Sensitivity
Insulin Sensitivity and Beta Cell Function After Carbohydrate Loading in Hip Replacement Surgery
The purpose of this study is to determine whether preload of carbohydrate or water before elective hip replacement improve insulin sensitivity and or beta cell function in human.
- Trial name
- NCT01774084
- Testing
- Experimental: PreOp, NutriciaNordica AB
- Where
- 2 sites in Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Overweight
Anti-obesity Effect of Koji-extracted Beverage Fermented With Pediococcus Pentosaceus LP28
This study is designed to evaluate the effect of koji-extracted beverage fermented with Pediococcus pentosaceus LP28 on BMI and body fat in overweight subjects.
- Trial name
- NCT02050555
- Testing
- Koji-extracted beverage fermented with Pediococcus pentosaceus LP28
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Diabetes Mellitus, Type 2
A Research Study to Check the Safety of NNC9836-0001 When Given to Healthy Participants and Participants With Type 2 Diabetes
The purpose of this clinical study is to determine if the study medicine NNC9836-0001 is safe and tolerable in healthy participants with overweight or obesity or who have type 2 diabetes (T2D).
- Trial name
- NCT07896109
- Testing
- NNC9836-0001
- Where
- Germany
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Glucose Intolerance, Exercise
The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults
The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this…
- Conditions
- Glucose Intolerance, Exercise, Vascular Function
- Trial name
- NCT05468255
- Testing
- removal of exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Gestational Diabetes, GDM
The MalaYsian GestatiOnal Diabetes and Prevention of DiabetES Study
Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy and is associated with adverse foetal, infant, and maternal outcomes.
- Conditions
- Gestational Diabetes, GDM, Pregnancy-Induced Diabetes
- Trial name
- MyGODDESS (NCT05204706)
- Testing
- MyManis app
- Where
- 3 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Hyperlipidemia, Ursodeoxycholic Acid
Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance
The purpose of this clinical trial is to understand whether the drug Ursodeoxycholic acid (UDCA) can prevent glucose intolerance in participants with hyperlipidemia who are taking statins. It will also assess the safety of UDCA.
- Conditions
- Hyperlipidemia, Ursodeoxycholic Acid, Statin Therapy, Glucose Intolerance
- Trial name
- URSTAR (NCT06684106)
- Testing
- Ursodeoxycholic acid (UDCA) 500 mg
- Where
- 2 sites in China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Energy Metabolism
Acute Effects of Caffeine on Mitochondrial Function in Peripheral Blood Mononuclear Cells
This randomized, double-blind, placebo-controlled crossover study will evaluate the acute effects of caffeine consumption on substrate utilization, resting energy metabolism, and mitochondrial function in peripheral blood…
- Trial name
- MITOCAFFEINE (NCT07873047)
- Testing
- Caffeine (5 mg/kg)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity, Infant
Health e-Baby: Trial to Reduce Obesity Risk Factors During the First 1,000 Days
Specific Aim: Feasibility of a Pilot Randomized Controlled Trial (RCT) in Pregnancy and Infancy to Reduce Childhood Obesity Risk Factors in Early Life.
- Trial name
- NCT05225649
- Testing
- Behavior Change Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Columbia University
Chronic Kidney Disease
Efficacy of the 6-point Diet
The dietary restriction of proteins and sodium is a cornerstone in the treatment of chronic kidney disease (CKD) and of its metabolic consequences. Dietary adjustments in CKD are complex and the patients' compliance is very low.
- Trial name
- PIS (NCT01865526)
- Testing
- Six point diet, Low protein diet
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federico II University
Nurse's Role
Nurse-led Therapeutic Education Effects in Glycemic Control and Knowledge of Type 1 Diabetes Mellitus Patients Under Hospital Transition
The goal of this interventional quasiexperimental study is to learn about the influence of therapeutic education carried out by nurses in the management and knowledge of patients with T1DM.
- Trial name
- NCT05766215
- Testing
- Therapeutic Education
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Obesity, Overweight and Obesity
Investigation of the Effects of a Bifidobacterium Breve Strain on Fat Loss in Healthy Adults
Overweight has become a critical issue in North America and the market value of weight loss products is expected to rise as the population becomes more health-conscious and aware of the risks associated with excess body weight.
- Trial name
- NCT04677738
- Testing
- B. breve strain
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Morinaga Milk Industry Co., LTD
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