Clinical trials: Metabolic Control
Diabetes Mellitus, Type 2
First Time in Human Study Using GSK2330672
The purpose of this study is to look at the safety and tolerability of increasing single doses of GSK2330672 in healthy volunteers.
- Trial name
- NCT01416324
- Testing
- 0.1 mg GSK2330672, 0.3 mg GSK2330672, 1 mg GSK2330672
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumonia, Vitamin D Deficiency
Kabul Vitamin D Supplementation Trial
Background: Pneumonia is the leading cause of childhood mortality, accounting for 19% of the 10.6 million deaths that occur each year1.
- Trial name
- NCT00548379
- Testing
- vitamin D
- Where
- 2 sites in Afghanistan
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Obesity, Gastro Esophageal Reflux Disease
Effect of Routine Anterior Crural Repair in De-Novo Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy
The purpose of the study is to evaluate the superiority of anterior crural repair during sleeve gastrectomy over no repair in decreasing the incidence of gastroesophageal reflux disease.
- Trial name
- NCT04884074
- Testing
- Standard Sleeve Gastrectomy plus Anterior Crural Repair, Standard sleeve gastrectomy (SSG, the control group)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Malnutrition
Effectiveness of Targeting Food Aid to Malnourished Children Compared to Targeting All Children Under Two Years
The objective of this study is to compare two approaches to targeting donated supplementary food to young children. The study compares the effectiveness of the widely-used curative approach where targeting is based on the child's…
- Trial name
- NCT00210418
- Testing
- Fortified food rations, Education and communication to improve feeding practices
- Where
- Haiti
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Childhood Obesity
A Theory Driven, Rurally Tailored, Family-Based, Telehealth Intervention for Childhood Obesity
This pilot trial aims to improve the lives of individuals in rural Indiana by addressing the leading cause of death, obesity. The purpose is to help children and their families develop healthy behaviors to decrease childhood…
- Trial name
- NCT04720703
- Testing
- Newsletters, Family-based Telehealth Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Indiana University
Healthy, Insulin Sensitivity
Effects of Different Doses of Pinitol on Carbohydrate Metabolism Parameters in Healthy Subjects
The purpose of this study was to assess the acute effects of increasing doses of pinitol on glucose tolerance and insulin sensitivity and to evaluate the absorption of pinitol after consumption of an oral nutritive…
- Trial name
- NCT01738763
- Testing
- Pinitol
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Pregnancy, Gestational Diabetes Mellitus, Class A2
Intrapartum Glycemic Control in GDMA2
This is a randomized, parallel, controlled, non-inferiority trial to assess the impact of a tight versus a more liberalized intrapartum glycemic control in gestational diabetic mothers on neonatal glycemia.
- Conditions
- Pregnancy, Gestational Diabetes Mellitus, Class A2, Neonatal Hypoglycemia
- Trial name
- NCT05647798
- Testing
- Blood sugar check every 2 hours, Blood sugar check every 4 hours
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Overweight, Childhood, Obesity in Children
The Bloom Study - a Safe and Healthy Start in Life
The aim of the Bloom Study is to promote healthy weight development among infants through a home-based health promoting intervention implemented in the Danish setting of community health nurses.
- Trial name
- NCT06705400
- Testing
- Multi-behavioural
- Where
- Denmark
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Iron Deficiency, Anaemia in Children
A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of…
- Trial name
- IHAT-Gut (NCT02941081)
- Testing
- IHAT, Ferrous Sulphate
- Where
- The Gambia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Type 1 Diabetes
A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes
This study will be conducted primarily to evaluate the effects of CT-868 on glucose homeostasis in participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT05794581
- Testing
- CT-868, Victoza
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Carmot Therapeutics, Inc.
Healthy Subjects, Pharmacokinetics of ASP8232
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of ASP8232 in Subjects With Renal Impairment and in Type 2 Diabetes Mellitus Subjects With Chronic Kidney Disease
This study consists of two parts. Part 1 evaluates the effect of renal impairment on the PK and PD of a single dose of ASP8232. In addition, the safety and tolerability will be assessed.
- Conditions
- Healthy Subjects, Pharmacokinetics of ASP8232, Pharmacodynamics of ASP8232, Chronic Kidney Disease (CKD)
- Trial name
- NCT02218099
- Testing
- ASP8232
- Where
- 3 sites in Bulgaria, Moldova and 1 more
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Obesity, Adult
Efficacy of Mindful Tai Chi on Obese or Overweight Adults: A Randomized Controlled Clinical Trial
Background: New weight-loss intervention programs are being studied to determine their effectiveness in helping overweight and obese individuals reach a healthy weight.
- Conditions
- Obesity, Adult, Healthy
- Trial name
- NCT01264029
- Testing
- Mindful Tai Chi Intervention, Mindfulness Meditation, Mall Walking
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Overweight or Obesity
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy Subjects
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-4729 injection in healthy subjects.
- Trial name
- NCT06762600
- Testing
- HRS-4729 injection, HRS9531 injection, Acetaminophen
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Patients With Cardiovascular Disease, Healthy Participants
OCTA in Cardiovascular Disease and Healthy Controls
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy…
- Trial name
- NCT07359664
- Testing
- Retinal vascular assessment using OCTA and SLDF
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Diabetes Mellitus, Type 2, Educational Problems
The Effect of Web-Based Education in Patients With Type 2 Diabetes
This research was designed as a randomized controlled study to develop a web-based training program and evaluate the program's impact on diabetes management.
- Trial name
- NCT04626531
- Testing
- Web-Based Education, Control Group
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Postprandial Hyperglycemia
Is Mid-morning Breakfast as Healthy as Early-morning Breakfast for Blood Sugar Control in Adolescent Girls?
Repeated, elevated levels of glucose (sugar) within the blood after eating can lead to type 2 diabetes. In adults, eating breakfast lowers blood glucose responses to subsequent meals when compared with skipping breakfast.
- Trial name
- NCT05000944
- Testing
- breakfast omission (BO), early-morning breakfast consumption (EM-BC), mid-morning breakfast consumption (MM-BC)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Psychological Distress, Protein Deficiency
The Effect of Plasma Donation Frequency on Donor Health
This project is a randomized controlled non-inferiority study that aims to cover knowledge gaps about the composition and development of plasma proteins, inflammation markers and mental health in Norwegian, voluntary, and unpaid…
- Conditions
- Psychological Distress, Protein Deficiency, Inflammation
- Trial name
- NCT05179200
- Testing
- Plasmapheresis, Whole blood donation
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sykehuset Innlandet HF
Healthy Subjects, Obesity
A Phase 1 Study of HEC88473 Injection in Healthy Subjects, Obese Subjects and T2DM Subjects
This is a single-center, randomized, double-blind, placebo-controlled, escalating single-dose and multiple-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HEC88473 injection in healthy…
- Conditions
- Healthy Subjects, Obesity, T2DM (Type 2 Diabetes Mellitus)
- Trial name
- NCT05943886
- Testing
- HEC88473 injection
- Where
- China
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Dongguan HEC Biopharmaceutical R&D Co., Ltd.
Healthy Volunteers
A Multiple Dose Safety And Pharmacokinetic (PK) Study Of PF-06427878 In Overweight-Obese, Otherwise Healthy Subjects
PF-06427878 is a new compound proposed for the treatment of hyperlipidemia. The primary purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics after 2 weeks of dosing of PF-06427878 in…
- Trial name
- NCT02855177
- Testing
- PF-06427878
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obesity and Metabolic Syndrome
The Effects of Early vs. Delayed Time-Restricted Eating on Metabolic Syndrome Parameters
This study aims to compare the effects of early and delayed time-restricted eating on metabolic syndrome parameters in obese women.
- Trial name
- NCT07096505
- Testing
- Early time restricted eating with calorie restriction, Delayed Time Restricted Eating with calorie restriction, Control group with calorie restriction
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- SINEM BAYRAM
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