Clinical trials: Metabolic Control
Healthy Volunteers
Study to Investigate the Influence of CKD-519 on 24-h Ambulatory Blood Pressure in Healthy Adult Volunteers
The purpose of this study is to determine influence of CKD-519 on 24-h ambulatory blood pressure after oral administration in healthy adult volunteers.
- Trial name
- NCT02916901
- Testing
- CKD-519 200mg
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Obesity
Impact of Employee Wellness Programme
The introduction of a wellness programme for workers employed in a clothing factory will improve quality of life, pain, attendance at work and levels of physical activity.
- Trial name
- NCT01625039
- Testing
- Employee wellness programme, Comparator (Once off educational session and educational materials)
- Where
- South Africa
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Hypercholesterolemia
Multiple Ascending Dose Study of SPC4955 in Healthy Subjects
The purpose of this study is to study safety and tolerability of SPC4955 in healthy subjects.
- Trial name
- NCT01365663
- Testing
- SPC4955, Saline 0.9%
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Santaris Pharma A/S
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Metabolic Syndrome, Premature Aging
The Safety and Efficacy Study of RiaGev in Healthy Adults
This current randomized, double-blind, comparator-controlled, cross over study investigates the efficacy and safety of RiaGev™ via evaluation of NAD+, ATP, glucose, insulin, glutathione, and cortisol levels in healthy adults of…
- Trial name
- NCT04483011
- Testing
- RiaGev
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bioenergy Life Science, Inc.
Sedentary Behaviors, Breaking Prolonged Sitting With Physical Activity
Frequency of Interrupting Sitting and Cognitive Function
Rationale: Sedentary behavior (SB) has been associated with impaired cognitive function in elderly, and negatively impacts glucose metabolism.
- Trial name
- FISCF (NCT06700187)
- Testing
- Interrupting sitting with walking breaks
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hyperlipidemia, Ursodeoxycholic Acid
Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance
The purpose of this clinical trial is to understand whether the drug Ursodeoxycholic acid (UDCA) can prevent glucose intolerance in participants with hyperlipidemia who are taking statins. It will also assess the safety of UDCA.
- Conditions
- Hyperlipidemia, Ursodeoxycholic Acid, Statin Therapy, Glucose Intolerance
- Trial name
- URSTAR (NCT06684106)
- Testing
- Ursodeoxycholic acid (UDCA) 500 mg
- Where
- 2 sites in China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Lifestyle Intervention, Non Communicable Chronic Diseases
Evaluation of the WARIFA App and Its Impact on Healthy Lifestyle
The goal of this study is to assess the effect of the WARIFA app on the adoption of healthy lifestyle behaviours related to Non-communicable diseases (NCDs), as well as in the management of Type 1 Diabetes (T1D).
- Conditions
- Lifestyle Intervention, Non Communicable Chronic Diseases, Type 1 Diabetes (T1D)
- Trial name
- NCT06918444
- Testing
- WARIFA app with AI, WARIFA app without AI
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Investigaciones Biomédicas y Sanitarias (iUIBS) de la Universidad de Las
Alzheimer Disease
Evaluating Simvastatin's Potential Role in Therapy
The purpose of this study is to see how simvastatin, a cholesterol-lowering drug, affects processes related to the development of Alzheimer's disease, including: 1) levels of a substance called beta-amyloid-42 found in the spinal…
- Trial name
- ESPRIT (NCT00486044)
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obesity & Overweight, Foot and Ankle Disorders
Effects of Whole-Body Vibration With Foot Core Exercises: A Randomized Controlled Trial
This randomized, single-blind clinical trial investigates whether adding whole-body vibration (WBV) to a supervised foot core exercise program improves ankle muscle strength, balance, and proprioception in overweight and obese…
- Trial name
- FoCo-WBV (NCT07556198)
- Testing
- Supervised Foot Core Exercise Training (No Vibration), Whole-Body Vibration via DKN Technology Xg-10 Pro
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Istinye University
Obese, Obesity, Morbid
Treatment of Periodontitis in Obese Individuals
Obesity and gum diseases are highly prevalent in all parts of the world. Obesity can negatively influence severity and progression rates of gum diseases.
- Conditions
- Obese, Obesity, Morbid, Periodontitis
- Trial name
- CLIMBEO (NCT03103204)
- Testing
- One-stage full-mouth disinfection with chlorhexidine
- Where
- Brazil
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Type 2 Diabetes Mellitus, Medical Education
Generative AI-Based Simulation for Diagnostic Communication in Type 2 Diabetes (DIALOGUE-DM2)
This randomized controlled trial evaluates the effectiveness of a generative artificial intelligence (AI)-based simulation program in improving diagnostic communication skills among medical students.
- Conditions
- Type 2 Diabetes Mellitus, Medical Education, Diagnostic Communication, Artificial Intelligence Simulation
- Trial name
- DIALOGUE-DM2 (NCT07252193)
- Testing
- AI-Based Simulation Training (DIALOGUE-DM2), Traditional Training
- Where
- Mexico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06570993)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Gestational Diabetes, GDM
The MalaYsian GestatiOnal Diabetes and Prevention of DiabetES Study
Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy and is associated with adverse foetal, infant, and maternal outcomes.
- Conditions
- Gestational Diabetes, GDM, Pregnancy-Induced Diabetes
- Trial name
- MyGODDESS (NCT05204706)
- Testing
- MyManis app
- Where
- 3 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Overweight Adults
Effects of a Soya-Based Fibre Beverage on Weight and Health in Overweight Adults
The goal of this intervention study is to evaluate the effect of soya-based dietary fiber beverage (SBB) in overweight adults. The main question it aims to answer is: Does the SBB effective in improving the weight and metabolic…
- Trial name
- SBB-WEIGHTLOSS (NCT07614178)
- Testing
- Soya-based dietary fibre beverage
- Where
- Malaysia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Hypercholesterolemia
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous (SC) Administered Alirocumab in Healthy Chinese Subjects
Primary Objective: To assess the safety and tolerability of ascending single SC doses of alirocumab in Chinese healthy subjects. Secondary Objectives: To assess the pharmacokinetic profile of a single SC dose of alirocumab.
- Trial name
- NCT02979015
- Testing
- alirocumab SAR236553 (REGN727)
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sanofi
Non-anemic Iron Deficiency
Treatment of Non-Anemic Iron Deficiency in Pregnancy
The objective is to investigate the treatment of non-anemic iron deficiency (NAID) and the impact on development of anemia later in pregnancy.
- Trial name
- NCT05423249
- Testing
- Ferrous sulfate, Prenatal, Docusate Sodium
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Obesity Prevention
HealthyW8_60+ Pilot
This pilot study will focus on men and women aged ≥60 years for a period of 3 months during which each participant will use the HLRS.
- Trial name
- HealthyW8 (NCT06816147)
- Testing
- Investigators will evaluate the acceptance and adherence to a healthy lifestyle recommender solution (HLRS), a digital app, among participants
- Where
- Luxembourg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Diabetes
Clinical Trial to Assess the Effects of Dairy on Insulin Sensitivity and β-Cell Function
The aim of this trial is to evaluate the effects of dairy product consumption on insulin sensitivity and pancreatic β-cell function in men and women at risk for the development of type 2 diabetes mellitus (T2DM) who habitually…
- Trial name
- NCT01936935
- Testing
- Low-fat dairy, Sugar-sweetened beverages
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Provident Clinical Research
Hypercholesterolemia
A Single Dose Escalation Study of PCSK9 Inhibitor (JS002) in Health Subjects
JS002 is a recombinant humanized Anti- PCSK9 monoclonal antibody; This is a phase Ia, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of a single…
- Trial name
- NCT04197817
- Testing
- JS002
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
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