Clinical trials: Metabolic Control
Gestational Diabetes Mellitus (GDM)
STRONG: SMART Trial
Gestational diabetes is a type of diabetes that develops during pregnancy and can increase the risk of health problems for both mothers and babies.
- Trial name
- NCT07920588
- Testing
- STRONG Group Prenatal Care, Usual Prenatal Care, Group-Based Gestational Diabetes Education
- Where
- American Samoa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Yale University
Deficiencies Micronutrient, Nutrition Disorders
Effect of Consuming Vitamin A-fortified Sugar on Serum Retinol Levels in Children
The increase in vitamin A deficiency (<20 mcg/dL) among children under five in Colombia (2010-2015) is a public health problem (27.3%).
- Trial name
- NCT07860060
- Testing
- white sugar fortified with retinol, refined white sugar for culinary use
- Where
- Colombia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Obesity, Pregnancy
Does Dietary and Lifestyle Counseling Prevent Excessive Weight Gain During Pregnancy? A Randomized Controlled Trial
The purpose of this study is to determine if an organized, consistent program of dietary and lifestyle counseling will prevent excessive gestational weight gain.
- Trial name
- WIP (NCT00792480)
- Testing
- Dietary and lifestyle counseling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carolinas Medical Center
Obesity, Normal Weight
Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)
The overall aim of the MEMORY study is to examine the concept of 'food memory' - how specific macronutrient compositions influence subsequent food preference and intake, and whether this differs across the BMI range from normal…
- Conditions
- Obesity, Normal Weight, Overweight
- Trial name
- MEMORY (NCT06752967)
- Testing
- High protein liquid test meal, High carbohydrate liquid test meal
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Obesity, Prevention & Control
KAN-DO: A Family-based Intervention to Prevent Childhood Obesity
The purpose of this study is to evaluate the efficacy of an intervention (KAN-DO: Kids \& Adults Now - Defeat Obesity) encouraging postpartum mothers and their preschool-aged children to work together to promote healthy eating…
- Conditions
- Obesity, Prevention & Control, Postpartum Period
- Trial name
- KAN-DO (NCT00563264)
- Testing
- KAN-DO
- Where
- 2 sites in United States
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Duke University
Visceral Obesity, Reflux Esophagitis
Adipokines and the Risk of Reflux Esophagitis
We aimed to risk faoctors for GERD and association between visceral obesity, plasma adipoline(leptin, adiponectin, IL-6, TNF-α)and development of reflux esophagitis in healthy Koreans.
- Trial name
- NCT01560598
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Polycystic Ovary Syndrome
The Effect of Escitalopram in PCOS
In a randomized study the investigators aim to characterize the effect of antidepressive medicine on quality of life, body composition, adrenal activity and glucose metabolism in PCOS.
- Trial name
- NCT05840692
- Testing
- Escitalopram 20 mg
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Impaired Glucose Tolerance, Fetal Macrosomia
Treatment of Impaired Glucose Tolerance in Pregnancy
The purpose of this study is to evaluate if treatment (insulin or diet) of pregnant women with impaired glucose tolerance (75-g OGTT with a fasting P-gluc <7.0 mmol/l and 2 h P-gluc >10.0 and <12.2 mmol/l) close to normoglycemia…
- Trial name
- TIP (NCT00625781)
- Testing
- Insulin aspart and Insulin human (isophane)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Chronic Diseases
A Cluster-randomized Controlled Knowledge Translation Feasibility Study in Alberta Community Pharmacies
Background: Despite evidence of benefit for pharmacist involvement in chronic disease management, the provision of these services in community pharmacy has been suboptimal.
- Trial name
- NCT02191111
- Testing
- Task-focused facilitation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obesity, Overweight
A Study of SHR-2906 Injection in Healthy Subjects With a Single Dose and in Obese Patients With Multiple Doses
This study is a randomized, double-blind, placebo-controlled, dose-escalation phase I clinical trial. This study consists of two parts: the single-dose escalation study (SAD) in healthy subjects and the multiple-dose escalation…
- Trial name
- NCT07280936
- Testing
- SHR-2906 Injection
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Diabetes Mellitus, Type 2, Healthy Males
A First in Human, Single Dose, Safety and Tolerability Study of MKC253 Inhalation Powder in Healthy Adult Males
26 subjects will be enrolled into 5 different dose groups. The trial will consist of a screening, a dosing and a follow-up visit.
- Trial name
- NCT00475371
- Testing
- MKC253 Inhalation Powder
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Prediabetes, Hyperglycemia
Benefit of IQP-VV-102 in Reducing Postprandial Glucose Level in Overweight Caucasian Subjects
In this trial, the investigational product , the active ingredients which has been proven to reduce postprandial glucose in healthy and diabetic patients, will be tested.
- Trial name
- NCT02541344
- Testing
- Dose 1 of IQP-VV-102, Dose 2 of IQP-VV-102
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
MELAS Syndrome, Mitochondrial Respiratory Chain Deficiencies
Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
The purpose of this First In Human study is to investigate the safety and tolerability of KL1333 after a single oral dose and to investigate the pharmacokinetic characteristics of KL1333 after a single oral dose.
- Trial name
- NCT03056209
- Testing
- KL1333 25 mg, KL1333 50 mg, KL1333 100 mg
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.
Diabetes Mellitus, Glycemic Control
Effect of Dry Roasted Peanuts and Boiled Peanuts on Glycemic Control
Research on glycemic control related to nuts or whole snack foods has focused primarily on tree nuts. Different processing and cooking methods have not been comprehensively analyzed to observe the effect on nutrient quality…
- Trial name
- NCT04171648
- Testing
- Roasted Peanut Treatment, Boiled Peanut Treatment
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Pregnancy, Body Weight Changes
Targeting Pregnancy-related Weight Gain to Reduce Disparities in Obesity
The purpose of this study is to find out whether a technology-base healthy lifestyle program is an acceptable and effective way for African-American mothers to improve their eating and activity during pregnancy, compared to usual…
- Conditions
- Pregnancy, Body Weight Changes, Behavioral, Obesity
- Trial name
- NCT02229708
- Testing
- Healthy Lifestyle Group
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Temple University
Osteoporosis
A Study to Assess the Effects of a Light Breakfast on the Safety, Tolerability, and Pharmacokinetics of Odanacatib (MK0822)
This study will assess the safety and tolerability of single doses of odanacatib (MK0822) when administered with a light breakfast.
- Trial name
- NCT00863525
- Testing
- odanacatib
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
NAFLD, Type 2 Diabetes
Study Visceral Adipose Tissue and Liver Stifness in a Retrospective Cohort of Diabetes Mellitus Patients
Non Alcoholic Fatty Liver Disease (NAFLD) is an emergent disease worldwide, and soon the leading cause of hepatic transplant in the USA.
- Trial name
- NCT04493814
- Where
- France
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Diabetic Cardiomyopathies, Type2 Diabetes
Effect of High-intensity Interval Training on Cardiac Function and Regulation of Glycemic Control in Diabetic Cardiomyopathy
According to data of the International Diabetes Federation (IDF), diabetes in general affects approximately 415 million people worldwide and this number is still increasing.
- Trial name
- NCT03299790
- Testing
- high-intensity interval exercise training (HIIT), moderate-intensity exercise training (MIT)
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Diabetes
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single-dose GZR4
This trial is conducted in China. The aim of this trial is to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of single-dose GZR4.
- Trial name
- NCT06548815
- Testing
- GZR4
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Overweight and Obesity
Effect of Transcranial Direct Current Stimulation (tDCS) and Probiotic Supplementation in Overweight Adults
The aim of the current study is to investigate and compare the effectiveness of probiotic supplementation and tDCS stimulation on risky decision-making related to food choices in overweight people.
- Trial name
- NCT06035718
- Testing
- Probiotic Blend Capsule, tDCS
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Tehran
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