Clinical trials: Metabolic Disorder, Glucose
Type 2 Diabetes Mellitus
Fasiglifam 25 mg BID vs 50 mg QD
To evaluate the efficacy of fasiglifam 25 mg twice daily (BID) and fasiglifam 50 mg once daily (QD) on glycemic control in adults with type 2 diabetes who are inadequately controlled on diet and exercise alone.
- Trial name
- NCT01982253
- Testing
- Fasiglifam
- Where
- 88 sites in United States, Bulgaria and 5 more
- Volunteers
- 10 people
- Sponsor
- Takeda
Gestational Diabetes, Weight Loss
Smartphone App to Restore Optimal Weight in Women With Recent Gestational Diabetes
Gestational diabetes (GDM) complicates about 20% of pregnancies in Singapore. These women are at high risk of developing type 2 diabetes years after pregnancy; seven times more likely than normal.
- Conditions
- Gestational Diabetes, Weight Loss, Diet Habit
- Trial name
- SPAROW (NCT03324737)
- Testing
- Interactive Smartphone App
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
Type 1 Diabetes
Assessment of a Decision Support Tool in Participants With Type 1 Diabetes
Type 1 diabetes (T1D) is a complex disease with a high risk of both hyper- and hypoglycemia which can lead to severe acute and chronic complications.
- Trial name
- NCT04428645
- Testing
- DailyDose Decision Support
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Oregon Health and Science University
Type 2 Diabetes Mellitus
A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers
This Phase I clinical study is to evaluate the safety/tolerability and pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 tablets).
- Trial name
- NCT02375139
- Testing
- DA-1229_01, E+M
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Type 2 Diabetes Mellitus
Effectiveness and Safety of Treatment of Insulin Glargine in Type 2 Diabetes Mellitus Following Glucagon-like Peptide-1 (GLP-1) Failure
Primary Objective: To assess the efficacy of insulin glargine as measured by changes of HbA1c levels from baseline in type 2 diabetes mellitus (T2DM) patients following GLP-1 failure.
- Trial name
- GAUDI (NCT01461577)
- Testing
- INSULIN GLARGINE HOE 901
- Where
- Japan
- Volunteers
- 89 people
- Sponsor
- Sanofi
Cardiovascular Disease, Diabetes Mellitus
LIFESTAT - Living With Statins, a Cross Sectional Study
Background Statins are cholesterol lowering drugs that are prescribed to lower the risk of cardio-vascular diseases (CVD). The use of statins has increased markedly and it is now one of the most prescribed drugs in the world.
- Trial name
- NCT02250677
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- University of Copenhagen
Obesity, Morbid, Metabolic Syndrome
Non-randomized Prospective Comparison Between SASI Bipartition and RYGB
The main aim of this project is to assess the safety and efficiency of the SASI Bipartition.
- Conditions
- Obesity, Morbid, Metabolic Syndrome, Bariatric Surgery Candidate, Postoperative Complications
- Trial name
- NCT04469712
- Testing
- SASI Bipartition, Gastric bypass
- Where
- Norway
- Volunteers
- 280 people
- Sponsor
- Aleris Hospital
Type 2 Diabetes Mellitus
Safety and Efficacy of Bexagliflozin Compared to Glimepiride as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
The purpose of this study is to investigate the effect of bexagliflozin compared to glimepiride as an add-on therapy to metformin in lowering hemoglobin A1c (HbA1c) levels in subjects with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT02769481
- Testing
- Bexagliflozin, Glimepiride
- Where
- 45 sites in United States, Germany and 2 more
- Volunteers
- 426 people
- Sponsor
- Theracos
Osteoarthritis, Knee, Diabete Type 2
Increased Blood Glucose Levels After Steroid Injection
a sample of 600 patients diagnosed as Knee osteoarthritis injected with 40 mg triamcinolone, recorded their morning fasting blood glucose levels for 7 days before injection used as the baseline blood glucose level, which was…
- Trial name
- NCT06228911
- Testing
- steroid (triamcinolone)
- Where
- Syria
- Volunteers
- 600 people
- Sponsor
- Syrian Private University
Tuberculosis, Diabetes Mellitus
Immunobiology of Diabetes and Tuberculosis
The study hypothesis is that type 2 diabetics have abnormal cell-mediated immunity to tuberculosis manifesting as altered cytokine responses by peripheral blood mononuclear cells (PBMCs).
- Trial name
- NCT00568854
- Testing
- BCG
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gastric Cancer With Metabolic Syndrome or Metabolic Disease
Prospective Cohort Study for Analyzing the Effect of Gastric Cancer Surgery to the Metabolic Syndrome and Insulin Resistance
Gastric cancer is still one of the most common malignance in Korea. Because of the popularity of regular check ups, early detection of gastric cancer has increased, consequently, the survival of the patients also has increased.
- Trial name
- NCT01714622
- Testing
- subtotal gastrectomy with gastroduodenostomy, subtotal gastrectomy with Roux-en-Y gastrojejunostomy,, total gastrectomy with Rou-en-Y esophagojejunostomy
- Where
- 3 sites in South Korea
- Sponsor
- Yonsei University
Diabetes Mellitus
Patient Education in NorthTrondelag Hospital Trust
The purpose of this randomised open study is to examine the effect of self-management program for diabetes patients.
- Trial name
- NCT00326222
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 146 people
- Sponsor
- Norwegian University of Science and Technology
Obesity
The Effects of Oral Glucose Compared to Sweetener Drinking on Hormonal/Metabolic Responses
The goal of this study is to determine the hormonal/metabolic reponse to ingestion of sugar compared to consuming artificial sweetened drink, and to evalute macronutrient consumption 24 hours post ingestion of the drinks.
- Trial name
- NCT01683929
- Testing
- glucose, sweetner
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Diabetes, Diabetes Mellitus, Type 2
Safety and Efficacy of Biphasic Human Insulin Compared to EX1000 in Type 2 Diabetes
This trial is conducted in Asia and Africa. This trial aims for a comparison of blood glucose control of biphasic human insulin 100 IU/mL and EX1000.
- Trial name
- NCT00698802
- Testing
- EX1000, biphasic human insulin
- Where
- 3 sites in India, South Africa and 1 more
- Volunteers
- 397 people
- Sponsor
- Novo Nordisk A/S
Coronary Artery Disease, Diabetes Mellitus
The Effect of Remote Ischemic Preconditioning on Diastolic Function in Coronary Artery Bypass Surgery Between Diabetic and Non-Diabetic Patients
This randomized controlled study aims to evaluate the effects of Remote Ischemic Preconditioning (RIPC) on diastolic function in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Diastolic Function
- Trial name
- NCT06841757
- Testing
- Remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alzahraa Khalil Marie
Type 2 Diabetes
Post-prandial Effects of Extra Virgin Olive Oil on Endothelial Function in Adults at Risk for Type 2 Diabetes
Purpose: The number of cases of adults with Type 2 diabetes has quadrupled since 1980. This increase in the number of cases of diabetes is attributed to changes in dietary patterns, which include an increase in the consumption of…
- Trial name
- NCT04025281
- Testing
- Extra Virgin Olive Oil, Refined Olive Oil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Griffin Hospital
Diabetes Mellitus Type 2 Without Complication, Polyneuropathies, Diabetic
Polyneuropathy in Diabetes Mellitus Type 2
This is a population-based study of type 2 diabetes patients with and without neuropathy recruited from the Danish National Type 2 Diabetes cohort (DD2).
- Conditions
- Diabetes Mellitus Type 2 Without Complication, Polyneuropathies, Diabetic, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- NCT02947828
- Where
- 2 sites in Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Type2 Diabetes, Major Depressive Disorder
Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes
This study will enroll participants who have been diagnosed with type 2 diabetes and are experiencing symptoms of depression. This study will look at an anti-depressant medication called vortioxetine (Trintellix).
- Trial name
- NCT03580967
- Testing
- Vortioxetine
- Where
- United States
- Sponsor
- Todd Doyle
Chronic Renal Failure (CRF), Renal Transplantation
Assessing the Prevalence of Metabolic Syndrome in Renal Transplantation
Metabolic syndrome (MS) is characterized by a series of metabolic and hemodynamic parameters such as hypertension (hypertension), abdominal obesity, dyslipidemia, abnormal glucose metabolism and insulin resistance, resulting in…
- Trial name
- NCT01753973
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes, Diabetes Mellitus, Type 1
Efficacy and Safety of Insulin Aspart vs. Human Insulin During Pregnancy by Women With Type 1 Diabetes
This trial was conducted in Europe, Middle East, North America and South America. The aim of this trial was to compare the use of an intensified insulin treatment with insulin aspart (NovoRapid®) versus human insulin (Actrapid®)…
- Trial name
- NCT00365170
- Testing
- human insulin, insulin aspart
- Where
- 95 sites in Argentina, Austria and 16 more
- Volunteers
- 419 people
- Sponsor
- Novo Nordisk A/S
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