Clinical trials: Metabolic Disorder, Glucose
Hydroxymethylglutaryl-CoA Reductase Inhibitors, Diabetes Mellitus
Statins in Patients With Type 2 Diabetes Mellitus and Previous History of Acute Coronary Syndrome
The purpose of this study was to compare the efficacy and safety of high dose atorvastatin (40 mg) versus high dose rosuvastatin (20 mg) in Egyptian type II diabetic patients with previous acute coronary syndrome history.
- Trial name
- NCT05306990
- Testing
- Atorvastatin 40 Mg Oral Tablet, Rosuvastatin 20 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Helwan University
Type 2 Diabetes Mellitus
A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)
This study assessed the safety and efficacy of MK-3577. The primary efficacy hypothesis was that, after 4 weeks of treatment, either the morning (AM) administration or the evening (PM) administration of MK-3577 provides superior…
- Trial name
- NCT00868790
- Testing
- MK-3577, Metformin
- Volunteers
- 118 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 1 Diabetes
Efficacy of Coordinated Insulin Boluses in Type 1 Diabetic Patients
A recent study suggests that, in Type 1 Diabetes (T1D) patients treated by insulin pumps, a better coordination of meal boluses and post prandial basal rate could reduce the importance of postprandial hyperglycaemias without…
- Trial name
- COBOL (NCT02229097)
- Testing
- Normal bolus, Coordinated bolus
- Where
- 3 sites in France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Toulouse
Type2 Diabetes Mellitus, Pre Diabetes
Investigating Plasma Biomarker Molecules Associated With the Progression of Prediabetes to Overt Type 2 Diabetes
There are an estimate 7 million people in the United Kingdom living with pre-diabetes. The increasing number of new cases of pre-diabetes presents a global health concern due to funding implications.
- Trial name
- NCT04851223
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- University of Roehampton
Prostate Cancer, Resistance Exercise
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose
Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM) and increased fat mass).
- Conditions
- Prostate Cancer, Resistance Exercise, Androgen Deprivation Therapy
- Trial name
- NCT03440879
- Testing
- Zoladex
- Where
- Norway
- Volunteers
- 23 people
- Sponsor
- Norwegian School of Sport Sciences
Type 1 Diabetes
Personalized Comprehensive Diabetes Support for Children With Newly Diagnosed Type 1 Diabetes
The goal of this clinical trial is to learn if access to a diabetes coach improves quality of life (QOL) for families of children with newly diagnosed type 1 diabetes. The main questions it aims to answer are: 1.
- Trial name
- NCT06057662
- Testing
- personalized comprehensive diabetes support
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Diabetes Type 1
Optimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Adults With Type 1 Diabetes: a Feasibility Study (D-stress Study)
Up to one in two adults with type 1 diabetes find living with and managing diabetes to be emotionally challenging. This 'emotional side' of diabetes - feeling worried, frustrated, overwhelmed, sad, burnt-out - is called diabetes…
- Trial name
- NCT07193446
- Testing
- D-stress study: The detection, prevention and management of diabetes distress for adults living with type 1 diabetes.
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Obesity and Overweight, Dietary Intervention
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.
The aim of the study is to determine the optimal plant-based dietary model in terms of weight loss and health that would be both acceptable and environmentally friendly dietary model based on limiting the consumption of meat and…
- Conditions
- Obesity and Overweight, Dietary Intervention, Vegetarian Diet, Vegan Diet
- Trial name
- VEGPREV (NCT06886490)
- Testing
- Mediterranean diet, Planetary diet, Lactovegetarian diet
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Warsaw
Diabetes Mellitus
The Relationship Between Voiding Dysfunction and Intravesical Sensory Threshold in Diabetes Women
The investigators will recruit a cross-sectional group of diabetic women in internist clinics. UDS will be applied for voiding function in each case.
- Trial name
- NCT00155610
- Testing
- intravesical current perception test
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Type 2
Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus
An AGE-rich diet can induce after 2-6 weeks persistent increases in mediators linked to vascular dysfunction (e.g. TNFα, VCAM-1) in people with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT00446810
- Testing
- Benfotiamine
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ruhr University of Bochum
Type 2 Diabetes Mellitus
Autologous Bone Marrow Mononuclear Cell Transplantation in Treating Type 2 Diabetes Mellitus
The study is aimed to evaluate the safety and efficiency of autologous bone marrow mononuclear cell transplantation in treating selective patients with type 2 Diabetes Mellitus.
- Trial name
- NCT01677013
- Testing
- BMMCT
- Where
- China
- Volunteers
- 1,026 people
- Sponsor
- Peking University Aerospace Center Hospital
Immunological Status, Healthy Volunteers
Critical Food Ingredients on Immunocompetence to Prevent the Risk and Development of Obesity/Metabolic Syndrome
Double-blind cross-over intervention where the volunteers were randomized into two groups who, after receiving nutritional counseling, received two formulations in the form of a cookie: Group 1, commercial formulation and Group…
- Conditions
- Immunological Status, Healthy Volunteers, Healthy Volunteers - Male and Female
- Trial name
- CricoImNut (NCT07496320)
- Testing
- Administration of a commercial cookie formulation, Immunonutritional_2
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Postoperative Delirium, Hip Fractures
Association Between Preoperative Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients
This retrospective study aims to collect electronic medical record data from Dandong central hospital spanning from January 2013 to November 2023.
- Conditions
- Postoperative Delirium, Hip Fractures, Hyperglycemia
- Trial name
- NCT06473324
- Where
- China
- Volunteers
- 2,031 people
- Sponsor
- Wenbo Ding
Diabetes Mellitus, Prediabetes
Effects of an Exercise and Lifestyle Education Program for People With Diabetes and Prediabetes
The purpose of this trial is to pragmatically investigate whether participation of people with diabetes and prediabetes in an Exercise and Lifestyle Education Program (i.e., exercise and education classes) results in better…
- Trial name
- NCT03914924
- Testing
- Exercise Program, Lifestyle Education Program
- Where
- 2 sites in Brazil
- Volunteers
- 240 people
- Sponsor
- Federal University of Juiz de Fora
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cardiometabolic Syndrome, Obesity and Cardiovascular Risk
Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic Risk
The increasing prevalence of obesity, its serious health consequences, and the substantial economic burden on healthcare systems underscore a pressing need for effective, long-term prevention strategies that can be implemented in…
- Conditions
- Cardiometabolic Syndrome, Obesity and Cardiovascular Risk, Overweight , Obesity
- Trial name
- NCT07806279
- Testing
- Bupropion 150 mg, Lyophilized powder from edible mushrooms, Lifestyle Management
- Where
- 3 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Uppsala University
Platelet Aggregation During Acute Myocardial Infarction
DPP-4 Inhibitors and Acute Myocardial Infarction:Effects on Platelet Function
Cardiovascular events are the main cause of mortality in diabetic patients ,on the other hand,during an acute myocardial infarction(AMI),hyperglycemia increases mortality and is related to different pathophysiologic processes.
- Trial name
- NCT02377388
- Testing
- sitagliptin OR saxagliptin
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- University of Sao Paulo General Hospital
Physical Activity, PreDiabetes
Exercise Promotion in Primary Care
The investigators conducted a pilot study to determine if telephone counseling, in a health care setting that routinely assesses physical activity of its members, is a feasible approach to improve physical activity among patients…
- Conditions
- Physical Activity, PreDiabetes, Diabetes
- Trial name
- EPPC (NCT03429088)
- Testing
- Motivational interviewing telephone counseling
- Volunteers
- 67 people
- Sponsor
- Kaiser Permanente
Vagus Nerve Stimulation, Insulin Sensitivity
Effect of Breathing Maneuvers on Peripheral Glucose Metabolism
Two important mechanisms play a major role in the pathogenesis of type 2 diabetes: insulin resistance of the target tissues and the impaired insulin secretion from pancreatic β-cells.
- Conditions
- Vagus Nerve Stimulation, Insulin Sensitivity, Deep Breathing Maneuver
- Trial name
- RESPI01 (NCT04150627)
- Testing
- deep breathing
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
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