Clinical trials: Metabolic Regulation
Insulin Sensitivity, Healthy Adult
Diaplex and Glycemic Control
The goal of this 16-week double-blind, placebo-controlled pilot study is to determine whether daily Diaplex supplementation improves insulin sensitivity and glycemic control in adults with elevated blood glucose levels, while…
- Trial name
- NCT07711587
- Testing
- Diaplex
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Obesity, Insulin Resistance
Plasma Triglyceride Extraction by The Muscle
Increased accumulation of fat into the muscles is associated with what is called insulin-resistant state, which is a pre-diabetic state.
- Trial name
- NCT01860911
- Testing
- Insulin, NG-monomethyl-L-arginine
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Insulin Resistance
Regulation of KATP Channels and Na+/K+ ATPase in Relation to Fatigue Development
To investigate the role of ATP sensitive K+ potassium channels and the Na+/K+ pump in the development of fatigue in healthy and in insulin resistant subjects.
- Trial name
- NCT03775902
- Testing
- Nicorandil
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cryotherapy, Training
Short to Long Effects of Whole Body Cryostimulation on Insulin Sensitivity Among Overweight
Therapeutic effectiveness of coldness in relieving pain and reducing inflammation has been known for many years now. Over that time, various coldness therapies have gained in popularity, including winter swimming, snow baths or…
- Conditions
- Cryotherapy, Training, Overweight, Insulin
- Trial name
- NCT04375969
- Testing
- whole body cryostimulation treatment, Connection WBC treatment and HIIT training, Control Group
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Childhood Obesity
Physical Activity and Screen-Time Regulations in Childcare Centers - Aim 1
The goal of this project is to examine the physical activity and screen-time environment of licensed childcare centers before and after the enactment of new state regulations.
- Trial name
- Pause and Play (NCT02751788)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Overweight
A Study of the Effects of Fish Protein Intake on Glucose Regulation in Overweight and Obese Adults.
The purpose of this study is to compare the possible health benefits of intake of proteins from salmon, herring, cod and milk on glucose tolerance in overweight and obese adults.
- Trial name
- FISK3 (NCT01641055)
- Testing
- Salmon protein hydrolysate, Herring protein hydrolysate, Cod protein
- Where
- Norway
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Emotional Eating, Emotion Regulation
ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating
This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in…
- Conditions
- Emotional Eating, Emotion Regulation, Overweight, Psychological Flexibility
- Trial name
- ACT-EE (NCT07559552)
- Testing
- ACT-Based Group Therapy, ACT-Based Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Obesity, Diabetes
Fibre and Appetite Regulation Trial (FART)
High intake of cereal fibre has been shown to be associated with reduced weight gain and improved insulin sensitivity. We hypothesize these effects are due to the short chain fatty acids derived from the bacterial fermentation…
- Trial name
- NCT00247455
- Testing
- Low fibre breakfast cereal (puffed rice/cornflakes), High fibre cereal (All Bran/Bran Flakes)
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Schizophrenia, Type 2 Diabetes Mellitus
Pfizer/IVGTT/Ziprasidone/Olanzapine
Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions.
- Trial name
- NCT00205725
- Testing
- Ziprasidone, Olanzapine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Intestinal Disorder, Inflammatory Bowel Diseases
Effect of Acupuncture on Mild to Moderate Active Crohn's Disease
To observe the clinical effect of acupuncture on Crohn's disease (CD) and its influence on brain function activity and the TRY-KYN metabolism level, and to screen the brain image markers of acupuncture on CD
- Conditions
- Intestinal Disorder, Inflammatory Bowel Diseases, Crohn Disease
- Trial name
- NCT04187820
- Testing
- acupuncture
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Body Weight Changes, Metabolic Syndrome
Evaluation the Effect of AKK Formula on Intestinal Microbiota Regulation and Body Composition
The AKK formula, a prebiotic blend, can effectively promote the proliferation of A. muciniphila. In this study, we attempt to explore the clinical efficacy of AKK formula for A. muciniphila proliferation and weight management.
- Trial name
- NCT06132269
- Testing
- AKK formula prebiotic sachet
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Healthy, Obese
Exercise Regulation of Human Adipose Tissue
The purpose of this study is to determine whether exercise training leads to changes in the white adipose tissue that are beneficial to the body's regulation of sugar and body weight.
- Conditions
- Healthy, Obese, Diabetes Mellitus, Type 2
- Trial name
- NCT03133156
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity, Menopausal Syndrome
Regulation of Cortisol Metabolism and Fat Patterning
The purpose of this study is to determine if estrogen or testosterone can affect cortisol levels and where fat builds up in our bodies.
- Trial name
- NCT00694733
- Testing
- Depo Lupron/Aromatase inhibitor, Estrogen cream
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
NAFLD, Overweight and Obesity
The Role of Dietary Carbohydrate and Fat Availability in the Regulation of Hepatic Lipid Content
The purpose of this study is to investigate dietary compositions effect on liverfat measured by magnetic resonance imaging.
- Conditions
- NAFLD, Overweight and Obesity, Metabolic Syndrome, Diabetes
- Trial name
- LICARB (NCT04581421)
- Testing
- High Carb Low Fat Diet, Low Carb High Fat Diet
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Obesity
Effects of Intravenous Infusions of Gut Hormones on Appetite and Metabolism.
The purpose of this study is to investigate the effects of intravenous infusion of two gastrointestinal hormones, PYY3-36 and GLP-1, alone and in combination, on appetite in healthy obese men.
- Trial name
- INGEAR-1 (NCT00940134)
- Testing
- PYY 3-36, GLP-1, saline infusion
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Growth Hormone as a Determinant of Weight Regulation
With the alarming increase in the prevalence of obesity, identifying factors that predispose individuals to weight-gain is of critical importance.
- Trial name
- NCT00355784
- Testing
- overfeeding, growth hormone treatment
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity
Determinants of Post-Exercise Eating Patterns
This study examines potential physiological and psychological determinants of food intake in response to exercise. Specifically, beyond measuring actual food consumption and physiological markers typically assessed during…
- Trial name
- DEEP (NCT03643315)
- Testing
- Exercise and Meal (EX), No-Exercise and Meal (NEX)
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Obesity
Blood Glucose and Body Fat Regulatory Effect of Peanut Skin Extract
The regulatory effects of the peanut skin extract (Sugarlock®) on body fat and blood glucose was demonstrated in a double-blind, placebo-controlled study. .
- Trial name
- NCT02537912
- Testing
- Sugarlock®
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Obesity, Diet
Effect of Carbonated Soft Drinks on Appetite-Regulation
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks…
- Trial name
- NCT00776971
- Testing
- Sugar-sweetened soft drink, Aspartame-sweetened soft drink, Semi-skimmed milk
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Postmenopausal Osteoporosis
Study on the microRNA Expression Level in Postmenopausal Osteoporosis
The miRNA plays an important regulation role in gene expression, and also closely related to bone metabolism. Previous research found that postmenopausal osteoporosis with kidney Yin deficiency syndrome (POP) is associated with…
- Trial name
- microRNA (NCT02128009)
- Testing
- osteoporosis
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Academy of Traditional Chinese Medicine