Clinical trials: Metabolic Surgery
Obesity
Harmonic Versus Electro Surgery in Lower Body Lift Procedures
The objective of this study is to determine if the use of The Harmonic™ (an ultrasonic surgical instrument) in Lower Body Lift procedures reduces volume and duration of wound drainage after surgery when compared to Electro…
- Trial name
- LBL (NCT00522171)
- Testing
- The Harmonic™ ultrasonic scalpel
- Where
- 2 sites in United States, Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
Colon Neoplasms, Crohn Disease (CD)
Feasibility Study of the SEGER Device in Laparoscopic Gastrointestinal Surgery
This is a first-in-human feasibility study designed to evaluate the safety and performance of the SEGER device in patients undergoing elective laparoscopic gastrointestinal surgery requiring intracorporeal anastomosis.
- Conditions
- Colon Neoplasms, Crohn Disease (CD), Obesity & Overweight
- Trial name
- SEGER-FIH (NCT07508592)
- Testing
- SEGER Device
- Where
- El Salvador
- Volunteers
- 10 people
- Sponsor
- Seger Surgical Solutions
Diabetes Mellitus, Type 2, Surgery
Carbohydrate Loading and Diabetes in Colorectal Surgery
The goal of this study is to evaluate the feasibility of conducting a large study that would assess the safety of carbohydrate drinks (i.e. juice) prior to elective colorectal surgery in patients with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Surgery, Surgery--Complications
- Trial name
- NCT04410419
- Testing
- Pre-operative carbohydrate drink
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- University of Alberta
Bariatric Surgery, Weight Loss
Social Isolation But Not Deprivation Involved in Employment Status After Bariatric Surgery.
This study looked at how bariatric surgery (weight-loss surgery) affects people's chances of getting a job, especially in a low-income area.
- Conditions
- Bariatric Surgery, Weight Loss, Employment, Obesity
- Trial name
- NCT06998953
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Type 2 Diabetes
Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines
The obesity and type 2 diabetes mellitus (T2DM) are among the most threatening health crisis for the 21st century. Currently, it is estimated that there are 205 million people with T2DM worldwide.
- Trial name
- PRODIGIES (NCT01974544)
- Testing
- Best medical treatment, gastric bypass, sleeve gastrectomy
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity, Type 2 Diabetes
The Impact of Hafnia Alvei on Weight Loss and Glycaemic Control After Bariatric Surgery
This study aims to investigate the effects of Hafnia alvei HA4597 TM supplementation on weight loss and glycemic control after bariatric surgery.
- Trial name
- NCT05170867
- Testing
- Hafnia alvei HA4597™
- Where
- Portugal
- Volunteers
- 49 people
- Sponsor
- Universidade Nova de Lisboa
Surgical View, Shoulder Tip Pain
Evaluation of Low Pressure Pneumoperitoneum in Bariatric Surgery (ELOPES Study)
This is a prospective study whereby it involves patients who are planned for bariatric surgery. In the bariatric surgery procedure, pneumoperitoneum pressure will be the experimental aspect in this study.
- Conditions
- Surgical View, Shoulder Tip Pain, Abdominal Pain
- Trial name
- NCT03179111
- Testing
- Pneumoperitoneum Pressure
- Where
- Malaysia
- Volunteers
- 94 people
- Sponsor
- Universiti Putra Malaysia
Asthma, Obesity
Contributing Factors in the Pathobiology of Airway Remodeling in Obesity
There are two aims for this study. The purpose of this study is to determine the effects of body weight and hormones on airway fibrosis (scarring) and lung function in obese \& lean asthma subjects compared to obese \& lean…
- Conditions
- Asthma, Obesity, Obesity, Morbid, Bariatric Surgery Candidate
- Trial name
- NCT03115632
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Gynecologic Cancer, Anemia
Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery)
Iron deficiency has been reported in approximately 35% of patients with a gynecologic malignancy. Blood transfusions are known to be immunosuppressive and carry immediate and long-term risks.
- Conditions
- Gynecologic Cancer, Anemia, Iron-deficiency
- Trial name
- FORGE II (NCT05407987)
- Testing
- Ferric derisomaltose
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- AHS Cancer Control Alberta
Obesity
Efficacy of Tirzepatide for Weight Management in Patients With Suboptimal Weight Loss After Bariatric Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Many people who have bariatric (weight-loss) surgery do not lose as much weight as expected, or they regain weight over time. This study will test whether a medicine called tirzepatide can help these patients lose more weight and…
- Trial name
- TirBaS (NCT07829198)
- Testing
- Tirzepatide
- Where
- 3 sites in Portugal
- Volunteers
- 70 people
- Sponsor
- Universidade do Porto
Obesity, Bariatric Surgery Candidate
BE Smart - Bariatric Patient - Empowerment in the Preparation and Follow-up of Bariatric Surgery Using the Smartvisit App (BESmart)
Obesity affects an increasing proportion of the population and is associated with numerous comorbidities that cause increased morbidity and mortality. The most effective therapy for morbid obesity is metabolic bariatric surgery.
- Trial name
- BESmart (NCT06061406)
- Testing
- smart visit app
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Wuerzburg University Hospital
Obesity
StomaphyX Versus Sham for Revisional Surgery in Post-Roux-en-Y Patients to Reduce Regained Weight
The Roux-en-Y gastric bypass (RNYGB) is a weight loss surgery that involves the creation of a small gastric pouch and rearrangement of the small intestine.
- Trial name
- NCT00939055
- Testing
- StomaphyX
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- EndoGastric Solutions
Type 2 Diabetes
Glargine U300 Hospital Trial
The purpose of this study is to find out if treatment with Glargine U300 when compared to Glargine U100 will result in similar sugar control in patients with Type 2 Diabetes (T2D), who are admitted to the hospital and then…
- Trial name
- NCT03013985
- Testing
- Glargine U300, Glargine U100, Glulisine Insulin
- Where
- 4 sites in United States
- Volunteers
- 247 people
- Sponsor
- Emory University
Obesity
Quality of Life Following Gastric Bypass Surgery.
A central goal of health care is to maximize patient functioning and well-being. This has prompted measurement of health-related quality of life (HRQOL) that encompasses physical, psychological, and social functioning.
- Trial name
- NCT02032199
- Where
- Denmark
- Volunteers
- 121 people
- Sponsor
- René Klinkby Støving
Diet, Healthy, Obesity, Visceral
NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery
Obesity is a major public health problem and is constantly on the rise. Therapeutic approaches based on dietary advice, physical activity and the management of psychological difficulties are not always sufficient to achieve a…
- Conditions
- Diet, Healthy, Obesity, Visceral, Bariatric Surgery Candidate
- Trial name
- NUTRACOB (NCT04942093)
- Testing
- With low-calorie, high-protein diet, Without low-calorie, high-protein diet
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Apneic Oxygenation, High-flow Nasal Cannulae
High-flow Nasal Oxygenation in Obese Patients During Apnea
Before going off to sleep patients are given oxygen to saturate blood with oxygen to extend time before a decrease in the level of oxygen in the blood occurs.
- Conditions
- Apneic Oxygenation, High-flow Nasal Cannulae, Bariatric Surgery, Anesthesia Induction
- Trial name
- NCT03195504
- Testing
- HFNC, CON (control)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Obesity, Morbid, Obesity
Study Testing Patient Decision Tools Related to the Risks and Benefits of Weight Loss Surgery
Morbid obesity currently affects more than 11 million US adults and is strongly associated with type 2 diabetes, cancer, cardiovascular disease, and arthritis.
- Conditions
- Obesity, Morbid, Obesity, Decision Aids, Bariatric Surgery
- Trial name
- POINT of View (NCT00666952)
- Testing
- Video Decision Aid, Booklet Decision Aid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kaiser Permanente
Pediatric Obesity, Metabolic and Bariatric Surgery
Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth
This is a Phase 3a, randomized, parallel-controlled trial designed to compare the early re-initiation of semaglutide, starting two weeks after sleeve gastrectomy, to standard care (no pharmacotherapy following surgery).
- Conditions
- Pediatric Obesity, Metabolic and Bariatric Surgery, Semaglutide
- Trial name
- NCT06934655
- Testing
- Semaglutide 2.4 mg
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Los Angeles
Obesity
Effects of Exercise Training in Individuals Undergoing Bariatric Surgery
The subject of the research; Effects of exercise training on cardiometabolic risk factors and functional capacity in individuals undergoing bariatric surgery.
- Trial name
- NCT05085015
- Testing
- Functional Exercise Training Group, Home Exercise Training Group
- Where
- Cyprus
- Volunteers
- 64 people
- Sponsor
- Eastern Mediterranean University
Obesity, Nausea and Vomiting, Postoperative
The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting
The purpose of this study is to assess the efficacy of Aprepitant + standard antiemetic regimen in reducing postoperative nausea and vomiting after laparoscopic gastric sleeve versus placebo + standard antiemetic regimen
- Trial name
- NCT05772676
- Testing
- Aprepitant
- Where
- Mexico
- Volunteers
- 400 people
- Sponsor
- Hospital General Tlahuac
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