Clinical trials: Metabolic Syndrome X
Cardiovascular Disease, Metabolic Syndrome
Canola Oil Multi-center Intervention Trial II
Building on the findings from the investigators previous study, COMIT I, the purpose of the COMIT II study is to supplement the DEXA measurement of body composition with a supplementary DEXA measurement of visceral adipose tissue…
- Trial name
- COMITII (NCT03054779)
- Testing
- Canola Oil, High oleic acid canola oil, Western diet oil combination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Penn State University
Metabolic Syndrome
Genetic Assessment of the Patients With Metabolic Syndrome
Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. The exact mechanisms of the complex pathways of metabolic syndrome are not yet completely known.
- Trial name
- GENMetS (NCT01268696)
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Metabolic Syndrome
The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
The aim of the present study is to characterize novel mechanisms whereby HDL may exert potent vasculoprotective effects independent of reverse cholesterol transport, in particular the effect of HDL on the regulation of the…
- Trial name
- NCT00346970
- Testing
- Extended-Release Niacin
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Metabolic Syndrome X
Comparison of Two Different Diets on Health Outcomes
The purpose of this study is to compare the effects of a low-carbohydrate diet and a high-carbohydrate, high-fiber diet, on insulin sensitivity and blood chemicals considered risk markers for heart disease, in persons with the…
- Trial name
- NCT00269646
- Testing
- Low-carbohydrate and high-carbohydrate diets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity, Metabolic Syndrome X
Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons
The purpose of this trial is to study the safety, tolerability and efficacy of an almond enriched hypocaloric diet on weight loss and weight maintenance, as well as on established and emerging cardiovascular risk factors in…
- Conditions
- Obesity, Metabolic Syndrome X, Hyperlipidemia, Hypertension
- Trial name
- NCT00194428
- Testing
- Almond enriched diet, Low fat caloric diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Temple University
Metabolic Syndrome, Obesity
Effects of Brisk Walking and Regular Intensity Exercise Interventions on Glycemic Control
Physical activity is shown to positively reduce the risk of developing both cardiovascular disease and type 2 diabetes. Current guidelines recommend 30-60 minutes of moderate intensity cardiorespiratory exercise five days per…
- Trial name
- NCT03227575
- Testing
- Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Plymouth State University
Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism
Growing up With the Young Endocrine Support System (YESS!)
Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out…
- Conditions
- Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism, Growth Hormone Deficiency, Combined Pituitary Hormone Deficiency
- Trial name
- YESS (NCT04252001)
- Testing
- YESS! game, Snake '97, Transition-toolkit
- Where
- 7 sites in Belgium, Netherlands and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- dr. Laura C. G. de Graaff-Herder
22q11 Deletion Syndrome, DiGeorge Syndrome
SNP-based Microdeletion and Aneuploidy RegisTry (SMART)
This multi-center prospective observational study is designed to track birth outcomes and perinatal correlates to the Panorama prenatal screening test in the general population among ten thousand women who present clinically and…
- Conditions
- 22q11 Deletion Syndrome, DiGeorge Syndrome, Trisomy 21, Trisomy 18
- Trial name
- SMART (NCT02381457)
- Where
- 21 sites in United States, Australia and 4 more
- Volunteers
- 20,960 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Metabolic Syndrome, Coronary Artery Disease
Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles
People with cardiovascular risk (CV) factors (obesity, diabetes, etc...) or established heart disease (such as coronary heart disease or chronic heart failure) often have cognitive dysfunction as compared to people without CV…
- Conditions
- Metabolic Syndrome, Coronary Artery Disease, Heart Failure
- Trial name
- COGNEX (NCT03018561)
- Testing
- Exercise and Cognitive testing
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Metabolic Syndrome X
Efficacy Study Regarding the Beneficial Effects of Omega-3 Fatty Acids on Cardiometabolic Health
Fish oil supplements (which are rich in omega-3 fatty acids) have been shown to provide cardiometabolic benefits to individuals of all ages.
- Trial name
- FOHS (NCT02042274)
- Testing
- Fish oil supplement
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Obesity, Inflammation
Long-term Investigation of Resveratrol in Obesity
The aim of this study is to investigate potential metabolic effects of resveratrol in men with metabolic syndrome(otherwise healthy).
- Conditions
- Obesity, Inflammation, Insulin Sensitivity, Osteoporosis
- Trial name
- LIRMOI (NCT01412645)
- Testing
- Resveratrol
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Metabolic Syndrome, Obesity
Body Weight and Vascular Function
An increased body mass impairs vascular function (VF), an important characteristic of subjects suffering from type 2 diabetes and a risk marker for cardiovascular diseases.
- Trial name
- NCT01675401
- Testing
- Weight-loss treatment, No-weight loss treatment
- Where
- Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
NAFLD
Effects of Overfeeding Followed by Weight Loss on Liver Fat Content and Adipose Tissue Inflammation
A. BACKGROUND Accumulation of fat in the liver due to non-alcoholic causes (NAFLD) is associated with hepatic insulin resistance, which impairs the ability of insulin to inhibit the production of glucose and VLDL .
- Trial name
- NCT02133144
- Testing
- overeating fat, overeating carbohydrate
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Cardiovascular Diseases, Metabolic Syndrome
Feasibility of Reducing Cardiovascular Disease Risk Factors in Hispanics Through a Family-Based Community Intervention
The purpose of this study is to evaluate the feasibility of a 6-month family-based community intervention to mitigate cardiovascular disease risk factors in Hispanic families in northern Colorado as measured through biometric…
- Trial name
- NCT05322876
- Testing
- Healthy Hearts Family Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poudre Valley Health System
Metabolic Syndrome, Diabetes
Nusantara Diet (Low Calorie and Low Sodium) for Metabolic Syndrome
The goal of this randomized clinical trial is to evaluate the effect of Nusantara Diet (Low Calorie and Low Sodium) for Metabolic Syndrome.
- Conditions
- Metabolic Syndrome, Diabetes, Hyperlipidemias
- Trial name
- NCT05566197
- Testing
- Diet Nusantara, Nutrition Counseling
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Hypogonadism, Metabolic Syndrome
Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men
The purpose of this study is to determine the effect of training and testim on Hypogonadism.
- Trial name
- NCT00700024
- Testing
- Testim, Strength training
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Metabolic Syndrome, Obesity
Genistein Stimulates Insulin Sensitivity Through Gut Microbiota
There is evidence that genistein present in soy can improve insulin resistance in rodents and humans with metabolic syndrome (MetS). However, it is not known if this improvement is associated with changes in the gut microbiota.
- Trial name
- GENISTEIN (NCT04105023)
- Testing
- genistein
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Obesity, Metabolic Disease
Beijing Children and Adolescents Metabolic Syndrome Study (BCAMS Study)
Base on enriched resources from the Metabolic Syndrome cohort in children, a long-term prospective cohort study will be carried out.
- Trial name
- BCAMS (NCT03421444)
- Testing
- No intervention
- Volunteers
- 19,593 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Vitamin D Deficiency, Diabetes Mellitus
Vitamin D Supplementation on Metabolic Syndrome Indicators Among Older Adults, Alborz Province, Iran
General objective: To assess the effect of vitamin D supplementation on metabolic syndrome among food insecure and vitamin D deficient older adults in Karaj city, Alborz province in Iran.
- Conditions
- Vitamin D Deficiency, Diabetes Mellitus, Hypertension, Lipid Metabolism Disorders
- Trial name
- NCT03193944
- Testing
- D-vitin, soft gelatin capsule (vitamin D3,50000 IU)
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alborz Medical University