Clinical trials: Metabolism Changes
Diabetes
Acute Whole Body Vibration Change the Glycemic and Lactate Levels
The type II diabetes is characterized by high levels of blood glucose followed by excessive insulin release so that the target cells become less sensitive and develop insulin resistance, maintaining hyperglycemic levels.
- Trial name
- NCT03542929
- Testing
- whole body vibration
- Where
- Brazil
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Healthy, Weight Loss
Adaptations of Exercise Energy Metabolism in Response to Weight Loss in Healthy Normal Weight People
More and more normal weight people are dieting in the general population. The NUTRILEX study aims to better understand the physiological adaptations in response to weight loss in healthy normal weight individuals.
- Conditions
- Healthy, Weight Loss, Body Weight, Diet Habit
- Trial name
- NUTRILEX (NCT05370222)
- Testing
- Dietary weight loss intervention
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Impaired Glucose Tolerance
The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women
This study will look at the effect of exenatide, a drug which has been approved for the treatment of type 2 diabetes, on body weight, appetite and energy expenditure among moderately obese women without diabetes.
- Trial name
- NCT00456885
- Testing
- exenatide
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetes Mellitus, Type 2
The Value of Adding Group Education (DESMOND Method) to the Standard Primary Care Education Practices in Changing Glycemic Control and Self-care Practices in Adults With Type II Diabetes Mellitus: A Randomized Controlled Intervention Study.
The goal of this clinical trial is to assess the outcome of delivering the health education in a group format using the DESMOND program compared to the standard health education in newly diagnosed adults with type 2 diabetes…
- Trial name
- NCT06513468
- Testing
- Group education session by DESMOND Program
- Where
- Qatar
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Primary Health Care Corporation, Qatar
Overweight, Obesity
Timing of Meals for Weight Loss
While eating the majority of energy earlier in the day appears to have a positive effect on weight and cardiometabolic outcomes, it is not clear how eating earlier in the day influences other behaviors that have a circadian…
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- TIME (NCT02204735)
- Testing
- Eat majority of calories in the morning, Eat the majority of calories in the evening
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
PreDiabetes
The Effect of Lifestyle Modification on the Risk of Prediabetes Among Patients Attending Outpatient Clinic.
Diabetes mellitus is a major global health challenge, with type 2 diabetes (T2DM) accounting for nearly 90% of all cases worldwide.
- Trial name
- NCT07462078
- Testing
- Lifestyle modification
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Mild Cognitive Impairment, Insulin Resistance
Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease
The purpose of the BEAM study is to compare the effects of a low-carbohydrate diet and a lowfat diet for adults with mild memory loss and adults with pre-diabetes.
- Trial name
- BEAM (NCT02984540)
- Testing
- Low-Carbohydrate Diet, Low-Fat Diet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Thinness
The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women
This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain.
- Conditions
- Obesity, Thinness, Weight Gain
- Trial name
- NCT00072917
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Health Education, Community, Diet, Food, and Nutrition
Change in Child-feeding Knowledge, Attitudes, and Practices With Nutrition Education Mass Media in Ghana
Optimal infant and young child feeding practices are largely inadequate in rural and poor households in Ghana. Child welfare clinics (CWCs) focus on immunization, supplementation, and growth monitoring and promotion (GMP)…
- Conditions
- Health Education, Community, Diet, Food, and Nutrition, Malnutrition, Infant Nutritional Sciences
- Trial name
- NCT02800564
- Testing
- Active mass media approach, Passive mass media approach
- Where
- 4 sites in Canada, Ghana
- Volunteers
- 689 people, healthy volunteers welcome
- Sponsor
- McGill University
Childhood Obesity
Childhood Obesity- Characteristics and Treatment
The study is evaluating the effect of a 14-session cognitive behavioural treatment for childhood obesity. The treatment is family based and 49 families with children with obesity, aged 8-12, will be recruited.
- Trial name
- NCT00961740
- Testing
- Cognitive Behavioural Therapy, Waitlist condition
- Where
- Norway
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Obesity, Overweight
Effect of Orlistat in Body Composition
The purpose of this study is to determine if a 24 week weight loss program with orlistat 60 mg will produce greater changes in body composition compared to placebo.
- Trial name
- NCT00752726
- Testing
- Orlistat
- Where
- 3 sites in United States, Sweden
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Weight Loss, Obesity
A Mentor-Based Approach to Long-Term Weight Loss
The purpose of this study to examine the effect of having a weight loss mentor on long-term weight loss in overweight adults.
- Trial name
- NCT00177697
- Testing
- behavioral weight loss program
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hot Weather; Adverse Effect, Kidney Dysfunction
Renal Considerations in the Heat Stress Recommendations (Aim2)
An epidemic of chronic kidney disease is occurring in laborers who undertake physical work outdoors in hot conditions. The reason for this is largely unknown, but may be related to kidney dysfunction caused by increases in body…
- Conditions
- Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia
- Trial name
- NCT05458843
- Testing
- Fluid replacement, No fluid replacement
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Weight Loss, Bariatric Surgery Candidate
Resting Metabolic Rate Testing in Bariatric Surgery Patients
This study evaluates if measuring resting metabolic rate (the number of calories the body burns at rest) before surgery can help predict successful weight loss after surgery.
- Trial name
- NCT03221543
- Testing
- ReeVue Indirect Calorimeter
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Osteoarthritis, Hip
Femoral Remodeling Following Total Hip Arthroplasty With OMNI Apex Modular™ and OMNI Apex ARC™ Stem Compared to Competitive Designs
This study compares the change in bone density which occurs after hip replacement with different femoral stem devices.
- Trial name
- NCT01359540
- Testing
- OMNI Apex Modular™ Hip Device, OMNI Apex ARC™ Hip Device
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity
Parents are children's primary role models, are food and physical activity gatekeepers, and create the structure/lifestyle environment within the home.
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Cognitive Change, Child Behavior
- Trial name
- HomeStyles-2 (NCT04802291)
- Testing
- HomeStyles-2: Obesity Prevention Program for Families with Children in Middle Childhood
- Where
- United States
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obesity, Overweight
Chewing Gum for Weight Loss
This is a randomized controlled trial of the effects of chewing gum on body weight. The investigators will randomly assign 200 overweight or mildly obese adults to one of two groups.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT00971347
- Testing
- Extra sugar-free chewing gum sticks, nutrition brochure
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pregnancy Diabetic
Predictive Value of Fetal Modified Myocardial Performance Index for Adverse Perinatal Outcomes in Late Onset Preeclampsia and Diabetes Mellitus
High-Risk Pregnancies complicated by gestational diabetes mellitus (GDM) and preeclampsia (PE) represent a significant global health challenge, affecting approximately 15-20% of all pregnancies.
- Trial name
- NCT07811050
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 1 Diabetes, Hypoglycemia
Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes Mellitus
This study is designed to investigate the effects of diabetes mellitus and its treatment upon the body's responses to low blood glucose (blood sugar) levels.
- Trial name
- NCT00580710
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Yale University
Metabolic Syndrome X, Cachexia
The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance
Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases.
- Conditions
- Metabolic Syndrome X, Cachexia, Insulin Resistance
- Trial name
- NCT00172614
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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