Clinical trials: Metabolism Changes, open to volunteers
Fasting, Dietary Fibre
Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health Benefits
This study builds on the knowledge that fasting provides metabolic health benefits and that prebiotic interventions can enhance the gut microbiome's metabolic output to likewise improve host health.
- Conditions
- Fasting, Dietary Fibre, Gut Microbiome, Metabolism Changes
- Trial name
- CoFFIe (NCT07691736)
- Testing
- Fibre Arm, Control Arm
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Body Composition Changes, Body Weight Change
Effect of Dairy Protein Yogourt vs Plant-based Yogourt on Body Weight, Body Composition, Bone Health and Gut Microbiota
The consumption of an adequate quantity of protein in the diet is essential to maintain a healthy body composition and functioning.
- Conditions
- Body Composition Changes, Body Weight Change, Metabolic Health, Bone Metabolism
- Trial name
- PROYO (NCT07578103)
- Testing
- Dairy yogurt, Plant based yogurt, No yogurt
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity & Overweight, Metabolism Changes
Acute and Chronic Effects of Obesity
The goal of this study is to understand if there are differences in the fat, muscle and metabolism of individuals who developed obesity during childhood versus those who developed obesity in adulthood.
- Conditions
- Obesity & Overweight, Metabolism Changes, Lipid Metabolism
- Trial name
- ACEO (NCT07515547)
- Testing
- Weight loss
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Concordia University, Montreal
Metabolism Changes, Psychology Functional Behavior
The Effects of Daytime, Nighttime, and Combined Heat Exposure on Human Health
Assess the acute effects of high-temperature exposure (including both daytime and nighttime conditions) on multiple physiological and psychological indicators, including cardiovascular, respiratory, neuropsychiatric, and…
- Conditions
- Metabolism Changes, Psychology Functional Behavior, Cardiovascular System, Respiratory System
- Trial name
- NCT07501923
- Testing
- Daytime or Nighttime High-Temperature Exposure, Daytime and nighttime neutral temperature exposure
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jian Cheng
Sleep, Metabolism Changes
Nighttime Synchrony of Your Nutrition and Circadian Health
Sleep is an important factor for overall health. This study will see how different light exposure patterns and food intake impact a person's metabolism (how the body breaks down food) when sleeping is reduced.
- Conditions
- Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors
- Trial name
- N-Sync (NCT07329283)
- Testing
- Central Clock Misalignment, Peripheral Misalignment
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Fat Mass, Risk Factors Cardiovascular Disease
Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Biomarkers of Aging
A large ongoing randomized, open-label trial aimed at evaluating the effects of two different dietary interventions, FMD and LD, on body composition and cardiovascular (CV) biomarkers in a real word population (NCT05698654) is…
- Conditions
- Fat Mass, Risk Factors Cardiovascular Disease, Epigenetic Aging, Metabolism Changes
- Trial name
- NCT07255300
- Testing
- fasting mimicking diet
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Hypertension, Vascular Function
Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.
This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health.
- Conditions
- Hypertension, Vascular Function, Fitness Testing, Metabolism Changes
- Trial name
- Antitension (NCT06823570)
- Testing
- Individualized exercise therapy, Lifestyle recommendations
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Sepsis, Septic Shock
Evaluation of Blood Protein O-GlcNAcylation Levels in Children
Stimulation of O-GlcNAcylation has been shown to be beneficial in several acute pathologies and different animal models, such as haemorrhagic and septic shock, and ischaemia-reperfusion (cerebral and cardiac).
- Conditions
- Sepsis, Septic Shock, Development and Health, Metabolism Changes
- Trial name
- CHANCE (NCT06754696)
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes
The Role of Nutrition in Muscle Function of Bariatric Surgery Patients
Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function…
- Conditions
- Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes, Muscle Function, Handgrip Strength Test, Protein Metabolism
- Trial name
- NCT06680492
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal