Clinical trials: Metabolites
Changes in Gut Microbiota, Gut Metabolites, Respiratory Symptoms, and Well-being Index
A Probiotic for Health Outcomes in Short-Term Overseas Travel
With the improvement of living standards, travel has become a common form of leisure. However, travelers often face changes in living environments, dietary habits, and sleep schedules, all of which can impact the gut microbiota…
- Trial name
- NCT07705659
- Testing
- Bifidobacterium longum, Maltodextrin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DiproBio (Shanghai) Co., Ltd.
Phase I and Phase II Metabolites of Berberine
Metabolic Differences Between Dihydroberberine and Micellar Berberine
Differences in metabolites of dihydroberberine (DHB) and micellar berberine (LipoMicel®, LMB) are investigated through a randomized study involving human volunteers.
- Trial name
- NCT06202157
- Testing
- LMB, DHB
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.
Bioavailability, Metabolites
Bioavailability Study of Hemp Phenolics
The aim is to determine the bioavailability of the polyphenol fraction form a commercially available hemp hull fiber at two different amounts in generally healthy adults.
- Conditions
- Bioavailability, Metabolites, Excretion
- Trial name
- NCT06098001
- Testing
- Low dose dietary fiber, High dose dietary fiber
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brightseed
Probiotics, Oral Health
Double-blind Clinical Trials of Probiotic Products in Oral Health.
In order to evaluate the effects of supplementary probiotics and their metabolites on oral environment and oral microbiota, Taiwan FDA No.
- Conditions
- Probiotics, Oral Health, Probiotic Metabolites
- Trial name
- NCT04289337
- Testing
- Combined probiotics (1), Combined probiotics (2), Combined heat-killed probiotics (1)
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Glac Biotech Co., Ltd
Asthma,, Pharmacokinetics,
Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.
The main purpose of the study is to compare the change of the AZD5069 Pharmacokinetic profile when administered with ketoconazole.
- Conditions
- Asthma,, Pharmacokinetics,, Cmax,, Tmax,
- Trial name
- NCT01735240
- Testing
- AZD5069, Ketoconazole
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pharmacokinetics of Darexaban and Metabolites, Healthy Subjects
To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)
The primary objective of this study is to determine the effect of ketoconazole on the blood concentrations of darexaban and its metabolites (drug degradation products).
- Trial name
- NCT01405989
- Testing
- darexaban, ketoconazole
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Pharmacokinetics of Darexaban and Metabolites, Healthy Subjects
To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)
The primary objective of this study is to determine the effect of rifampicin on the way the body handles darexaban and its metabolites (drug degradation products).
- Trial name
- NCT01406002
- Testing
- darexaban, Rifampicin
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc