Clinical trials: Metastatic Malignant Neoplasm to Femur
Proximal Femoral Metastases
A Randomized Trial to Assess Patient Quality of Life and Function After Alternative Surgeries for Pathologic Fractures of the Femur
The purpose of this study is to look at two different types of surgeries regularly used for treating cancer that has spread to and weakened the thigh bone (femur).
- Trial name
- NCT02164019
- Testing
- long-stem cemented hemiarthroplasty (LSCH), intramedullary nailing (IMN), questionnaires
- Where
- 6 sites in United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Metastatic Malignant Neoplasm to Femur
Femoral Bone Metastases
Bone is a common site of metastasis for a range of malignancies. Bone metastases have the potential to cause significant morbidity including pain, impairment of ambulation and reduced functional independence.
- Conditions
- Cancer, Metastatic Malignant Neoplasm to Femur, Risk of Fracture
- Trial name
- NCT01428895
- Testing
- Surgery Alone, Combined Surgery and Radiation therapy
- Where
- 2 sites in Canada
- Volunteers
- 180 people
- Sponsor
- University Health Network, Toronto
Pathological Fracture of Hip, Bone Metastases
Evaluation of the Performance of Y-STRUT® Medical Device to Strengthen Pre-fractural Tumour-induced Lesions at the Level of the Proximal Femur
HIPPON 100 is a national, multicentre, prospective, retrospective, descriptive and non-interventional study, in patients having a Y-STRUT® medical device implanted to prevent a high risk of impending pathological fracture.
- Trial name
- NCT03579212
- Testing
- Y-STRUT® (Hyprevention, Pessac, France)
- Where
- 4 sites in France
- Volunteers
- 16 people
- Sponsor
- Hyprevention
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Metastases to Bone, Metastatic Breast Cancer
Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study
Osteolytic bone metastases and myeloma bone lesions are responsible of long bone and vertebral fractures leading to restricted mobility, surgery and medullar compression that severely alter quality of life and that have a huge…
- Conditions
- Metastases to Bone, Metastatic Breast Cancer, Metastatic NSCLC
- Trial name
- MEKANOS (NCT04170634)
- Testing
- Evaluation of the fracture risk using data from routine qCT (quantitative Computed Tomography) scan and numerical simulation
- Where
- 12 sites in France
- Volunteers
- 220 people
- Sponsor
- Hospices Civils de Lyon