Clinical trials: Metformin
Bladder Cancer, Diabetes
BLADDER CANCER SCREENING AMONG DIABETIC PATIENTS
patients om metformin from diabetic clinic were checked for bladder cancer
- Trial name
- NCT02505516
- Testing
- metformin
- Where
- Ghana
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UFUOMA MILLER FAKPOR
Type 2 Diabetes
Clinical Trial to Evaluate the Efficacy and Safety of DW1026C1 or DW1026C2
A Randomized, Double-blind, Multi-center, Placebo-controlled, Phase III Trial to Evaluate the Efficacy and Safety of DW1026C1 or DW1026C2 Add-on to Metformin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin…
- Trial name
- NCT07076056
- Testing
- DW1026C1, DW1026C2, DW1026S
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Type 2 Diabetes Mellitus
A 12-week Study To Evaluate PF-06291874 Once a Day in Adults With T2DM Inadequately Controlled On Metformin
The purpose of this study is to determine whether PF-06291874 is effective in the treatment T2DM
- Trial name
- NCT02554877
- Testing
- PF-06291874
- Where
- 38 sites in United States, Canada
- Volunteers
- 206 people
- Sponsor
- Pfizer
Epidermal Melasma, Facial Hyperpigmentation
Topical Metformin Versus Triple Regimen for Epidermal Melasma
Melasma is a common skin condition that causes dark brown patches, mainly on sun-exposed areas of the face. It is often persistent, may recur after treatment, and can affect a person's quality of life.
- Trial name
- MET-MEL (NCT07779811)
- Testing
- Topical 30% metformin cream, Topical Triple Regimen
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Combined Military Hospital, Pakistan
Diabetes Mellitus, Type 2
A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
The purpose of this study is to see if GSK1292263 is safe and well-tolerated when administered to type 2 diabetics, and to get preliminary information about whether it may be effective in the treatment of type 2 diabetes.
- Trial name
- NCT01119846
- Testing
- GSK1292263, Sitagliptin
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- GlaxoSmithKline
Type 2 Diabetes Treated With Insulin
Study to Evaluate the Safety and Efficacy of Oral Insulin Formulation in Type 2 Diabetes Mellitus Subjects
The aim of the study was to compare the pharmacodynamic properties of different doses of regular human insulin administered in capsule form twice daily in a randomised twelve-week open-label trial.
- Trial name
- NCT06473662
- Testing
- Oral insulin
- Where
- United Kingdom
- Volunteers
- 153 people
- Sponsor
- Roger New
Non-Alcoholic Fatty Liver Disease, Type2 Diabetes
Antidiabetic Effects on Intrahepatic Fat
This was a 24-week single-center, open-label, parallel controlled group comparing gliclazide, liraglutide, and metformin effects on diabetes with nonalcoholic fatty liver disease.
- Trial name
- NCT03068065
- Testing
- Liraglutide, Metformin, Gliclazide
- Where
- China
- Volunteers
- 87 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetes Mellitus, Type 2
Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%)
The present study is designed to evaluate the efficacy and safety of fixed combination therapy of vildagliptin and metformin (25/1000 mg bid) in patients with type 2 diabetes inadequately controlled with prior metformin…
- Trial name
- NCT00728351
- Testing
- vildagliptin + metformin, metformin
- Where
- 63 sites in United States, France and 3 more
- Volunteers
- 317 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Kidney Disease, Cardiovascular Disease
Metformin in Kidney Disease
Chronic kidney disease (CKD) is a major global health problem associated with substantial costs and resource utilization. Currently, CKD affects more than 500 million people worldwide.
- Conditions
- Chronic Kidney Disease, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT02252081
- Testing
- metformin
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- VA Office of Research and Development
Type 2 Diabetes Mellitus
Diabetes Treatment With Glucobay in Combination With Metformin
In this prospective, non interventional, observational Post Marketing Survelliance study data are obtained on the efficacy, safety and tolerability of Glucobay treatment on top of metformin under daily life treatment…
- Trial name
- NCT01612741
- Testing
- Acarbose (Precose/Glucobay, BAYG5421)
- Where
- India
- Volunteers
- 19,509 people
- Sponsor
- Bayer
Type 2 Diabetes
MiTy Kids (Metformin in Women With Type 2 Diabetes in Pregnancy Kids Trial)
The prevalence of diabetes in pregnancy is rising in all maternal age groups. There is increasing evidence that in-utero exposure to maternal diabetes is associated with an increased risk of obesity and type 2 diabetes in…
- Trial name
- NCT01832181
- Where
- Canada
- Volunteers
- 287 people
- Sponsor
- Mount Sinai Hospital, Canada
Type 2 Diabetes Mellitus, Hypercholesterolemia
Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.
This is a 16-week double-blind, placebo-controlled (for colesevelam hydrochloride (HCl)) study in the type 2 diabetic subjects and pre-diabetic subjects.
- Conditions
- Type 2 Diabetes Mellitus, Hypercholesterolemia, Pre-diabetes
- Trial name
- NCT00570739
- Testing
- Metformin HCl tablets and Colesevelam tablets, Colesevelam
- Where
- 31 sites in United States, Colombia and 2 more
- Volunteers
- 502 people
- Sponsor
- Daiichi Sankyo
Type 2 Diabetes Mellitus
Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects
To demonstrate the bioequivalence of 500 mg and 1000 mg Glucophage tablets manufactured by BMS relative to the respective strengths of 500 mg and 1000 mg Diabex tablets marketed in Australia by Alphapharm in the fed state
- Trial name
- NCT01068730
- Testing
- metformin (Diabex), metformin (Glucophage™)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Spina Bifida, Neuromuscular Diseases
Metformin in Children With Motor Deficit
Obesity with insulin resistance in the paediatric population provides an increasing challenge. Children with neurological or neuromuscular diseases are even more prone to obesity: their locomotor impairment leads to an…
- Trial name
- NCT00720161
- Testing
- Metformin
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetes Mellitus, Type 2, Hyperglycemia
Oral Peri-operative TIming of Metformin (or) Salsalate to Improve Non-cardiac Surgery Glucose Control
Hypothesis: In surgical patients with type 2 diabetes, taking either metformin or salsalate on the morning of surgery will reduce the incidence of hyperglycemia, inflammation and even surgical site infections, without any obvious…
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia, Perioperative/Postoperative Complications, Salsalate to Improve Non-cardiac Surgery Glucose Control
- Trial name
- OPTIM(i)SING (NCT03816488)
- Testing
- Metformin, Salsalate
- Sponsor
- McMaster University
Type 2 Diabetes
Efficacy and Safety of QLG1091 vs Rybelsus as add-on to Metformin in Subjects With Type 2 Diabetes
This study is to evaluate the efficacy and safety of QLG1091 vs Rybelsus as add-on to Metformin in Subjects With Type 2 Diabetes. The primary objective is to demonstrate equivalence of QLG1091 and Rybelsus.
- Trial name
- NCT07487103
- Testing
- QLG1091, Rybelsus
- Volunteers
- 478 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Diabetes Mellitus, Type 2
The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy
Objective: To observe the effect of alogliptin combined with metformin on pulmonary function in obese patients with type 2 diabetes inadequately controlled by metformin monotherapy (500 mg, bid po, for at least 3 months), and…
- Trial name
- NCT02798172
- Testing
- Alogliptin and Metformin
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Fourth People's Hospital of Shenyang
Type 2 Diabetes Mellitus
South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus
The primary objective of this study is: To investigate whether insulin aspart with meals is better than a standard treatment with insulin NPH at bedtime, evaluated by HbA1c.
- Trial name
- SDDS (NCT00121966)
- Testing
- Insulin Aspart, Insulin NPH, Metformin
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Odense University Hospital
Bone Fracture
Metformin Effect on Fracture Healing in Post-Menopausal Women
study the effect of metformin drug on fracture healing of patients with high risk of delayed fracture healing or non-union and correlating this to serum irisin myokine level.
- Trial name
- NCT03845153
- Testing
- Metformin Retard 850 mg
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
Type 2 Diabetes, Dyslipidemia
Metformin/Rosuvastatin Combination Therapy With in Patients With Type 2 Diabetes and Dyslipidemia
Compare the Efficacy and Safety of Metformin/Rosuvastatin Combination Therapy With Metformin or Rosuvastatin Monotherapy in Patients With Type 2 Diabetes and Dyslipidemia
- Trial name
- NCT02827903
- Testing
- Metformin + Rosuvastatin
- Where
- 33 sites in South Korea
- Volunteers
- 237 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.