Clinical trials: Methamphetamine, open to volunteers
Substance Related Disorders
Testing Implementation Strategies to Scale-up a Multicomponent Continuum of Service Intervention for Families Involved in Systems With Parental Opioid and Methamphetamine Use
This study will explore how to expand the Just Care for Families (JCFF) program beyond its current sites in Oregon, while addressing two main challenges: the developer team cannot provide ongoing support to every new program, and…
- Trial name
- NCT07365293
- Testing
- Just Care for Families (JCFF), Just Care for Families (JCFF) App, Just Care for Families (JCFF) App Feedback
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Chestnut Health Systems
Methamphetamine Use Disorder
Methamphetamine Cue-reactivity
In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation with abstinence from methamphetamine use (MUD) and examine…
- Trial name
- NCT07086014
- Testing
- Cognitive Reappraisal
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Methamphetamine Abuse, Substance Use Disorders
rTMS for Craving in Methamphetamine Use Disorder
The primary aim of this project is to use a randomized single-blind sham-controlled study to investigate if high frequency repetitive transmagnetic stimulation (HF-rTMS) can modulate cue-induced craving in adult methamphetamine…
- Conditions
- Methamphetamine Abuse, Substance Use Disorders, Stimulant Dependence, Methamphetamine-dependence
- Trial name
- NCT03470480
- Testing
- Real Repetitive transcranial magnetic stimulation, Methamphetamine visual cues, Neutral visual cues
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Methamphetamine Use, Common Mental Disorders (CMD)
Friendship Bench for Women Who Use Methamphetamine in Vietnam
The high comorbidity of mental health issues and meth use in women worsens both their mental health and meth use outcomes. The study team proposes to evaluate the potential of Friendship Bench to be used as a low-threshold…
- Trial name
- FB-WWUM (NCT06789523)
- Testing
- Friendship Bench, Usual psychiatric care
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- Hanoi Medical University
Depression, Anxiety
Creatine for Depressed Male and Female Methamphetamine Users
Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users Assess creatine's effect on methamphetamine use Assess the safety of creatine in male methamphetamine users with depression
- Conditions
- Depression, Anxiety, Methamphetamine Dependence
- Trial name
- NCT02568878
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Montana State University
Alcohol Use Disorder (AUD), Alcoholism
Role of Pavlovian Mechanisms for Control Over Substance Use
During the first funding period (1st FP), the investigators developed a novel full Pavlovian-to-instrumental transfer (PIT) task that allows assessing both, general and specific PIT to investigate whether specific PIT differs…
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders, Cannabis Use Disorder
- Trial name
- ReCoDe (NCT06701487)
- Testing
- fMRI imaging (BOLD), sMRI (structure), Pavlovian-to-instrumental transfer (PIT) paradigm
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technische Universität Dresden
Methamphetamine Use Disorder
Non-Abstinence Outcomes in Methamphetamine Use Disorder
Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral change, preventing adoption of this endpoint in clinical trials.
- Trial name
- RCT (05) (NCT07226596)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- William Stoops
Methamphetamine Use, Heart Failure
Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement
The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology…
- Trial name
- PEER-Heart (NCT06461962)
- Testing
- Treatment as Usual, Telehealth-Cardiology
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Healthy Adult Male and Female Volunteers
Safety and PK Study of BICX104 With or Without Bupropion Compared to Vivitrol
Naltrexone (NTX), an opioid receptor antagonist, has a longstanding history of safe and effective use for the treatment of addictive disorders.
- Trial name
- NCT07269873
- Testing
- BICX104 naltrexone implantable pellet, Bupropion 150 mg XL, Naltrexone (depot)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BioCorRx Pharmaceuticals Inc
Methamphetamine Use Disorder
Randomized Controlled Trial of Tirzepatide for Methamphetamine Use Disorder
This is a phase 2, randomized, double-blind, placebo-controlled, parallel-group trial evaluating the tolerability, safety, and preliminary efficacy of tirzepatide for the treatment of individuals with moderate or severe…
- Trial name
- T-STEM (NCT07825857)
- Testing
- Tirzepatide
- Where
- 4 sites in United States
- Volunteers
- 228 people
- Sponsor
- University of Texas Southwestern Medical Center
Methamphetamine-dependence
Glutide for Ending Methamphetamine
GEM is a two-phase study to evaluate the use of semaglutide (Wegovy) for the treatment of methamphetamine use disorder (MeUD). The first phase is a pilot study, which will be an open-label, single-arm pilot study of 25…
- Trial name
- GEM (NCT07204249)
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
Methamphetamine-Associated Heart Failure, Methamphetamine-Associated Pulmonary Arterial Hypertension
Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
The purpose of this study is to evaluate the feasibility and preliminary effectiveness of increasing control over stimulant use and physical health through incentivized rehabilitation (INSPIRE).
- Trial name
- INSPIRE (NCT07915882)
- Testing
- Increasing control over stimulant use and physical health through incentivized rehabilitation, Usual Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Michael Incze
Methamphetamine Use Disorder, Methamphetamine Induced Psychosis
ECG Findings in Methamphetamine Use
This prospective cohort study aims to examine and compare electrocardiogram (ECG) parameters in subjects diagnosed with Methamphetamine Use Disorder (MUD) and Methamphetamine-Induced Psychotic Disorder (MP) during inpatient…
- Trial name
- NCT07459244
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Substance Abuse, Decision Making, Shared
Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose Prevention
Oregon's decision makers (e.g., community service providers, public health, justice, advocacy groups, payers) are calling for comprehensive, current, and trusted data to inform how they allocate resources to improve substance use…
- Conditions
- Substance Abuse, Decision Making, Shared, Implementation Science, Decision Making
- Trial name
- D2A Oregon (NCT06852170)
- Testing
- Co-Design Sessions (CDS), Data products
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
HIV Prevention
Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals
This research study is testing a new behavioral therapy called Episodic Future Thinking or EFT can help people reduce drug use and risky sexual behaviors while helping them adhere to their HIV prevention medication (PrEP).
- Trial name
- NCT06745947
- Testing
- EFT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
HIV, Methamphetamine Disorders
PrEP Readiness Interventions for Sustained Motivation (PRISM)
This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI) for optimizing entry or re-entry into the HIV prevention or care…
- Trial name
- PRISM (NCT06637436)
- Testing
- Motivational Interviewing (MI), Contingency Management (CM)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Florida International University
Methamphetamine Disorders
Reliability, Validity, and Acceptability of a Novel Visual Scale for Estimating Daily Methamphetamine Use Among People Who Use Methamphetamine
PROJECT RESIN: This study is examining the reliability, validity, and acceptability of a novel visual scale for estimating daily methamphetamine use among people who use methamphetamine.
- Trial name
- PROJECT RESIN (NCT07464873)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Phillip Coffin, MD, MIA
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Use Disorder
This trial tests whether psilocybin-assisted treatment can help adults stop using methamphetamine. Participants receive a single oral dose of psilocybin during a supervised session, paired with brief cognitive behavioral therapy…
- Trial name
- NCT07774702
- Testing
- Psilocybin (single oral capsule administered at one of two dose levels, Dose A or Dose B; specific doses withheld during conduct)., Manualized cognitive behavioral therapy platform (2 preparation + 2 integration sessions).
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Peter Hendricks
PrEP Adherence, Methamphetamine Use Disorder
CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM
The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use…
- Conditions
- PrEP Adherence, Methamphetamine Use Disorder, HIV
- Trial name
- CHAMPION (NCT07213258)
- Testing
- CHAMPION Intervention, Delayed CHAMPION Package
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Methamphetamine Use Disorder
Semaglutide for Treatment of People With Methamphetamine Use Disorder: the SHIFT Study
Methamphetamine use disorder is a major public health concern in Australia and globally. GLP-1 medications such as semaglutide (e.g.
- Trial name
- SHIFT (NCT07509112)
- Testing
- 12 weeks of weekly subcutaneous semaglutide injection
- Where
- 5 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Kirby Institute