Clinical trials: Methamphetamine
Methamphetamine, Amphetamine Dependence
Study of Medical Treatment for Methamphetamine Addiction
Currently there are no medications approved for the treatment of methamphetamine addiction. Bupropion is an antidepressant that is approved by the Food and Drug Administration (FDA) for the treatment of depression and for…
- Conditions
- Methamphetamine, Amphetamine Dependence, Pharmacogenetics, Methamphetamine Dependence
- Trial name
- BUP PGx (NCT00833443)
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Use Disorder
Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine]
This study will evaluate the behavioral effects of methamphetamine during maintenance on placebo, duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated human laboratory methods.
- Trial name
- NCT04178993
- Testing
- Methamphetamine, Methylphenidate, Duloxetine
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Craig Rush
Methamphetamine-dependence, Rectal Gonorrhea
Inflammation in Methamphetamine and STIs (IMSTI)
This clinical trial aims to investigate the effects of a decline in methamphetamine use on rectal inflammatory cytokine levels, substance use contexts, and HIV/STI risk behavior.
- Conditions
- Methamphetamine-dependence, Rectal Gonorrhea, Rectal Chlamydia
- Trial name
- IMSTI (NCT05162391)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
Studying Amphetamine Withdrawal in Humans
Methamphetamine use is very common in the US and is associated with serious medical and psychiatric problems. There has also been a significant increase in the number of patients entering treatment for methamphetamine dependence…
- Trial name
- NCT01215929
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arkansas
Continuous Methamphetamine Abuse
Monoamine Antagonist Therapies for Methamphetamine Abuse Prazosin
This protocol will test the safety, effectiveness and the metabolism and action of prazosin as a potential therapy for methamphetamine abuse. This will be accomplished by performing a series of human laboratory studies.
- Trial name
- MATMA (NCT01178138)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Methamphetamine
Topiramate for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess the efficacy and safety of topiramate as compared to placebo in reducing methamphetamine use in subjects with methamphetamine dependence.
- Trial name
- NCT00345371
- Testing
- Topiramate
- Where
- 8 sites in United States
- Volunteers
- 140 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine, Alcohol
Intermittent Naltrexone Among Polysubstance Users
Naltrexone, a µ-opioid receptor antagonist, is a promising agent for methamphetamine-using and binge-drinking men who have sex with men (MSM).
- Trial name
- Project iN (NCT01723384)
- Testing
- Intermittent Oral Naltrexone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Amphetamine-related Disorders
Long-term Behavior Change - 1
The purpose of this study is to determine if different reinforcement procedures (i.e., schedules) produce different patterns of long-term abstinence from methamphetamine.
- Trial name
- NCT00158197
- Testing
- contingency management voucher
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- Friends Research Institute, Inc.
Methamphetamine Dependence
Pilot Study of Entacapone for Methamphetamine Abuse
Addiction to methamphetamine is a serious health problem. There are no medications that a doctor can give someone to help them stop using methamphetamine.
- Trial name
- NCT02058966
- Testing
- Entacapone, Methamphetamine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Methamphetamine Use Disorder
Bupropion in the Treatment of Methamphetamine Dependence
Methamphetamine dependence is a significant drug use disorder in the Midwest. While a number of psychosocial and pharmacological treatments have been studied, no specific treatments for methamphetamine have been identified.
- Trial name
- NCT00572234
- Testing
- bupropion SR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Methamphetamine Dependence, Methamphetamine Abuse
Buspirone as a Candidate Medication for Methamphetamine Abuse
Methamphetamine use disorders are an unrelenting public health concern. Intensive research efforts have yielded behavioral interventions that reduce methamphetamine use, however, these interventions are not universally effective…
- Trial name
- NCT01843205
- Testing
- Methamphetamine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Methamphetamine Use Disorder
The Effects of Suvorexant on Sleep, Stress, and Cue-reactivity in Methamphetamine Use Disorder
The purpose of this study is to determine the effects of SUVO on sleep, stress, and cue reactivity/craving and to evaluate the preliminary safety and side effects profile of suvorexant (SUVO)
- Trial name
- NCT05711862
- Testing
- suvorexant (SUVO)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The University of Texas Health Science Center, Houston
Methamphetamine Abuse, Methamphetamine Dependence
Safety Assessment of Atomoxetine With MA IV Administration
This is a study of 4 nontreatment seeking individuals who were MA-dependent and the safety and tolerability of atomoxetine. This double-blind, placebo-controlled, within-subjects study is to determine the safety and tolerability…
- Trial name
- NCT01019707
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Intoxication (Disorder)
Meth-OD: A Study of IXT-m200 in Patients With Toxicity From Methamphetamine Overdose
The hypothesis of this multisite Phase 2a study is that IXT-m200 will be well-tolerated in patients with acute mild to moderate METH toxicity.
- Trial name
- Meth-OD (NCT04715230)
- Testing
- IXT-m200, Lorazepam, Haloperidol
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- InterveXion Therapeutics, LLC
Methamphetamine-dependence, Postpartum Abstinence
PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of 200 mg oral micronized progesterone twice daily…
- Trial name
- NCT05128071
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Utah
Methamphetamine Dependence
Modafinil vs Placebo for the Treatment of Methamphetamine Dependence
Modafinil is a non-amphetamine type stimulant that acts as a wakefulness-promoting drug, and is approved for managing symptoms of narcolepsy (i.e., daytime somnolence).
- Trial name
- Modafinil (NCT00469508)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence, Methamphetamine Withdrawal
Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study
Methamphetamine use has escalated in recent years. Methamphetamine use has also spread throughout the country. Although much information has been gathered on the treatment of cocaine abuse, very little information has been…
- Trial name
- NCT00653263
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Arkansas
Methamphetamine-dependence, Methamphetamine Abuse
Study of Antibody for Methamphetamine Outpatient Therapy
This study evaluates the ability of IXT-m200 to change methamphetamine concentrations in blood and alter the way methamphetamine feels.
- Trial name
- STAMPOUT (NCT03336866)
- Testing
- IXT-m200
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- InterveXion Therapeutics, LLC
Methamphetamine Dependence
Modafinil for Methamphetamine Dependence
Fifty methamphetamine dependent treatment-seeking volunteers will be enrolled in this 10 week, double bind, placebo controlled, randomized clinical trial to receive either modafinil or placebo.
- Trial name
- NCT00859573
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Arkansas
Healthy
Effects of MDMA on Emotional and Social Memories
The purpose of this study is to examine the effects of MDMA on encoding and retrieval of emotional and social memories in healthy young adults.
- Trial name
- NCT03050541
- Testing
- MDMA
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Chicago