Clinical trials: Methamphetamine Addiction
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Addiction
The primary purpose of this study is to preliminarily determine if the use of psilocybin to promote abstinence from methamphetamine is feasible and well tolerated in populations such as those found in Northern Louisiana.
- Trial name
- NCT06899594
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kevin Murnane
Opioid-use Disorder, Cocaine Use Disorder
Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives
Combatting the rise of the opioid epidemic is a central challenge of U.S. health care policy. A promising approach for improving welfare and decreasing medical costs of people with substance abuse disorders is offering incentive…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use
- Trial name
- NCT04927143
- Testing
- App-Based Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wake Forest University Health Sciences
Methamphetamine Use Disorder
TACS Intervention for Methamphetamine Addiction
In 2021, nearly 296 million people worldwide used psychoactive substances, highlighting a significant need for effective interventions for disorders such as Methamphetamine Use Disorder (MUD).
- Trial name
- tACS for MUD (NCT06288997)
- Testing
- Active transcranial alternating current stimulation
- Where
- 5 sites in China
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center
Crystal Methamphetamine Abuse, Crystal Methamphetamine Dependence
Behavioral Activation and HIV Risk Reduction for Men Who Have Sex With Men With Crystal Meth Abuse
The purpose of this study is to research a new behavioral treatment to reduce sexual risk-taking in men who have sex with men (MSM) who abuse crystal methamphetamine (crystal meth), and are at risk for HIV acquisition.
- Trial name
- NCT01255280
- Testing
- Behavioral Activation Therapy and Risk Reduction Counseling (BAT-RR), Information, Motivation, Behavioral skills change approach to sexual risk reduction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Methamphetamine Addiction, Crystal Meth Addiction
An Assessment of the Safety of Varenicline in Methamphetamine-dependent Volunteers
More people worldwide use amphetamine-type stimulants than any illicit drug besides cannabis, and methamphetamine (MA) abuse and dependence is the fastest growing drug problem in the United States.
- Conditions
- Methamphetamine Addiction, Crystal Meth Addiction, Amphetamine Addiction
- Trial name
- NCT00713479
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
An Study of Aripiprazole in the Treatment of Methamphetamine Dependence
Methamphetamine substance use is common worldwide. No approved pharmacologic treatments for methamphetamine dependence exist. Aripiprazole are Second generation antipsychotics，but have different pharmacological effects of…
- Trial name
- NCT01813656
- Testing
- Aripiprazole
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Wei Hao
Methamphetamine Dependence
Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence
Methamphetamine dependence is a serious public health problem, with methamphetamine abusers being at risk for significant morbidity and mortality, including HIV.
- Trial name
- NCT02034201
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Arkansas
Methamphetamine-dependence
Repetitive dTMS Intervention for Methamphetamine Addiction
A growing body of evidence suggests a wide range of brain areas including medial prefrontal cortex (mPFC), dorsolateral prefrontal cortex (DLPFC) and other subcortical regions, such as anterior cingulate cortex (ACC) are critical…
- Trial name
- NCT04202926
- Testing
- real coil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Shanghai Mental Health Center
Methamphetamine-dependence, Rectal Gonorrhea
Inflammation in Methamphetamine and STIs (IMSTI)
This clinical trial aims to investigate the effects of a decline in methamphetamine use on rectal inflammatory cytokine levels, substance use contexts, and HIV/STI risk behavior.
- Conditions
- Methamphetamine-dependence, Rectal Gonorrhea, Rectal Chlamydia
- Trial name
- IMSTI (NCT05162391)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Methamphetamine-dependence, Substance Abuse
Safety Interaction Trial Ibudilast and Methamphetamine
This study is designed to collect data to determine whether a medication, ibudilast, is safe for use as a potential treatment for methamphetamine-dependent people.
- Trial name
- NCT01217970
- Testing
- Ibudilast 20mg, Ibudilast 50mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
Tolerability and Safety of 30, 45, and 60 mg of Sublingual Lobeline. - 1
The purpose of this study is to assess safety and pharmacokinetics of sublingual lobeline in healthy normal volunteers.
- Trial name
- NCT00519259
- Testing
- Lobeline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine Addiction
Robot-Assisted Intelligent Rehabilitation Treatment for Methamphetamine Use Disorders.
The purpose of this research is to evaluate the efficacy and safety of Robot-assisted rehabilitation intelligent system as a virtual stand-alone treatment, delivered with minimal clinical monitoring compared with treatment as…
- Trial name
- NCT04531384
- Testing
- robot-assisted rehabilitation intelligent treatment, standard psychotherapy treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Mental Health Center
Cocaine Use Disorder, Methamphetamine Abuse
rTMS for Stimulant Use Disorders
The purpose of the study is to determine feasibility of repetitive transcranial magnetic stimulation (rTMS) for individuals with moderate to severe cocaine or methamphetamine use disorder (CUD/MUD).
- Conditions
- Cocaine Use Disorder, Methamphetamine Abuse, Cocaine Dependence, Methamphetamine Dependence
- Trial name
- CTN-0108 (NCT04907357)
- Testing
- rTMS
- Where
- 4 sites in United States
- Volunteers
- 129 people
- Sponsor
- Medical University of South Carolina
Stimulant Use Disorder, Cocaine Use Disorder
LDART for Stimulant Use Disorder
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a digital intervention called LDART in adults with stimulant use disorder.
- Conditions
- Stimulant Use Disorder, Cocaine Use Disorder, Methamphetamine Use Disorder
- Trial name
- LDART (NCT07221396)
- Testing
- LDART, Psychoeducational booklet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
HIV Infections, Methamphetamine-dependence
Stimulant Use and Methylation in HIV
This study will leverage extracted leukocyte DNA specimens from a completed NIH-funded project to examine the efficacy of a behavioral intervention model that reduced stimulant use on DNA methylation over 6 months.
- Conditions
- HIV Infections, Methamphetamine-dependence, Methamphetamine Abuse
- Trial name
- NCT05916989
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Florida International University
Methamphetamine-dependence, HIV-1-infection
Contingency Management for PrEP Adherence and/or Methamphetamine Use
Use of crystal methamphetamine (MA) leads to changes in sexual risk behavior, adherence to HIV prevention tools, immune response to infection, and tissue inflammation that collectively increase risk for HIV transmission among…
- Trial name
- C-MAX (NCT04563962)
- Testing
- Contingency Management-ART, Contingency Management-Methamphetamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
Risk and Protective Factors for Rural Methamphetamine Dependence
The primary goal of this study is to identify factors which may put a person that has used methamphetamine at greater risk for mental and physical health problems and social problems and factors that may lessen the risk for these…
- Trial name
- NCT00882037
- Where
- 2 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Methamphetamine Dependence
Efficacy and Safety of CDP-choline in Patients With Methamphetamine Dependence
The purpose of the study is to determine if cytidine 5'diphosphocholine (CDP-choline, a naturally occurring chemical in your body) has efficacy in reducing the methamphetamine craving of the subjects with methamphetamine…
- Trial name
- NCT01007539
- Testing
- CDP-choline
- Where
- 2 sites in South Korea
- Volunteers
- 31 people
- Sponsor
- Seoul National University Hospital
Methamphetamine Dependence, Substance Abuse
Varenicline-Methamphetamine Interaction Study (2008)
The primary aim of the study is to determine the safety and tolerability of treatment with Varenicline in methamphetamine-dependent volunteers.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT00733967
- Testing
- Varenicline
- Sponsor
- Baylor College of Medicine
Craving, Depression, Anxiety
Non-invasive Brain Stimulation in Patients With Methamphetamine Use Disorder
The study aims to apply the intermittent theta burst transcranial magnetic stimulation (iTBS) treatment and evaluate the effect in improving craving, affective symptoms, and cognitive function for those participants in the…
- Conditions
- Craving, Depression, Anxiety, Amphetamine Addiction
- Trial name
- NCT05535101
- Testing
- Intermittent theta burst transcranial magnetic stimulation (iTBS)
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch