Clinical trials: Methamphetamine Disorders
Nasal Congestion
Steady State Kinetics of l-Methamphetamine and Validation of Sensitivity of Dose Estimation
The intent of this study is to see if the rate that the body breaks down l-methamphetamine (l-MA) could be used as an accurate estimate for the rate that the body breaks down d-methamphetamine (d-MA).
- Trial name
- NCT00829634
- Testing
- l-methamphetamine, d-methamphetamine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Pacific Medical Center Research Institute
Amphetamine-Type Substance Use Disorder
Floatation-REST in Methamphetamine Use Disorder: A Pilot Study
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 50 individuals receiving treatment for…
- Trial name
- NCT05799209
- Testing
- Float Pool, Float Chair
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Methamphetamine Use, Common Mental Disorders (CMD)
Friendship Bench for Women Who Use Methamphetamine in Vietnam
The high comorbidity of mental health issues and meth use in women worsens both their mental health and meth use outcomes. The study team proposes to evaluate the potential of Friendship Bench to be used as a low-threshold…
- Trial name
- FB-WWUM (NCT06789523)
- Testing
- Friendship Bench, Usual psychiatric care
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- Hanoi Medical University
Amphetamine-Related Disorders
A Cognitive Behavioral Therapy-Based Text Message Intervention for Methamphetamine Dependence
This Phase I behavior therapy development study seeks to improve treatment outcomes for methamphetamine (MA)-dependent subjects by developing a novel cognitive behavioral therapy- (CBT-) based short message service (SMS) text…
- Trial name
- NCT01899313
- Testing
- CBT- based SMS text messaging intervention, CBT group therapy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- California Pacific Medical Center Research Institute
Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers
Effectiveness of Stress Management Training Program For Expressed Emotions in Caregivers of Drug Induced Psychosis Patients Specially Methamphetamine
The main purpose of this study is to evaluate the effectiveness of a Stress Management Training (SMT) program in reducing stress levels among caregivers of individuals suffering from methamphetamine ("ice") addiction and…
- Conditions
- Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers, Stress Cause Expressed Emotion and Burden
- Trial name
- NCT07714642
- Testing
- O'Connor's (2003) Stress Management Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Methamphetamine-dependence, Methamphetamine Abuse
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder
The primary objective of this study is to evaluate the efficacy of extended release naltrexone plus bupropion XL (XR-NTX/BUP-XL) compared to matched injectable and oral placebo (iPLB/oPLB) in reducing methamphetamine (MA) use in…
- Trial name
- NCT06233799
- Testing
- extended-release naltrexone (XR-NTX), extended release bupropion (BUP-XL) tablets (BUP-XL), iPLB
- Where
- 11 sites in United States
- Volunteers
- 360 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine Use Disorders
Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorder
Repetitive transcranial magnetic stimulation (rTMS) was used to treat methamphetamine use disorder in previous studies, while the evidence-based protocols still required.
- Trial name
- NCT03736317
- Testing
- real mPFC cTBS, real dlPFC iTBS, real dlPFC iTBS + real mPFC cTBS
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Stress Physiology, Stress Reaction
The Human Stress Response in a Simulated ED Setting
Stress is important for health. As emergency departments (EDs) are often stressful places, a better understanding of the human stress response is important for understanding how and why patients respond as they do when they come…
- Conditions
- Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence
- Trial name
- NCT04317482
- Testing
- Standard social stress task, Stressful experience in the ED
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Methamphetamine Addiction
Efficacy of Adaptive, Gamified Digital Therapeutics Intervention for Individuals With Methamphetamine Use Disorder in Community Rehabilitation
This study evaluates the efficacy of a comprehensive, adaptive digital therapeutics (DTx) smartphone application compared to treatment as usual (TAu) for individuals with Methamphetamine Use Disorder (MUD) receiving…
- Trial name
- NCT07319325
- Testing
- WonderLab Harbor+ (Adaptive DTx), Standard Community Counseling
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Methamphetamine Abuse
Digital Therapeutics Smartphone Application for Methamphetamine Use Disorder
One hundred participants were recruited and randomized into a digital therapeutics (DTx) group (n=52) and a treatment as usual (TAU) group (n=48).
- Trial name
- NCT05550493
- Testing
- Cognitive Behavioral Therapy, Counseling, Approach Bias Modification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Use Disorder
This trial tests whether psilocybin-assisted treatment can help adults stop using methamphetamine. Participants receive a single oral dose of psilocybin during a supervised session, paired with brief cognitive behavioral therapy…
- Trial name
- NCT07774702
- Testing
- Psilocybin (single oral capsule administered at one of two dose levels, Dose A or Dose B; specific doses withheld during conduct)., Manualized cognitive behavioral therapy platform (2 preparation + 2 integration sessions).
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Peter Hendricks
Substance Use Disorders, Opioid Use Disorder
Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR) device in substance use disorder (SUD)…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder
- Trial name
- EDITOR (NCT06434818)
- Testing
- EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Evon Medics LLC
Methamphetamine Use Disorder, Methamphetamine Induced Psychosis
ECG Findings in Methamphetamine Use
This prospective cohort study aims to examine and compare electrocardiogram (ECG) parameters in subjects diagnosed with Methamphetamine Use Disorder (MUD) and Methamphetamine-Induced Psychotic Disorder (MP) during inpatient…
- Trial name
- NCT07459244
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Substance-Related Disorders
Brain Electrophysiological Study(EEG/ERP) on Opiate Addicts Treating by Bilateral NAc/ALIC Deep Brain Stimulation
Drug addiction is compulsive and spontaneous drug-taking behavior which is characterized by non-medical usage, long and repeated exposure to addictive drugs and gradually increasing drug-taking dosage and frequency,and become a…
- Trial name
- NCT02594306
- Testing
- Emotional pictures stimulation system, Deep brain stimulation, adjacent contact stimulation
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Methamphetamine Use Disorder, Transcranial Magnetic Stimulation
Deep TMS of Neural Circuits Associated With Stimulant Use Disorder
This study aims to evaluate the efficacy of deep transcranial magnetic stimulation (dTMS) as a treatment for Veterans with a methamphetamine use disorder (MUD).
- Trial name
- NCT06578429
- Testing
- Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Active
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Methamphetamine Use Disorder, Substance Use Disorder
Closed-loop TMS for the Core Clinical Features of the Methamphetamine Use Disorder
The goal of this clinical trial is to evaluate whether closed-loop transcranial magnetic stimulation (TMS) can improve core clinical symptoms in individuals with methamphetamine use disorder (MUD), such as cue-reactivity and…
- Conditions
- Methamphetamine Use Disorder, Substance Use Disorder, Cue-reactivity, Craving
- Trial name
- NCT07154160
- Testing
- Closed-loop TMS, Conventional TMS, Random TMS
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Shanghai Mental Health Center
Opioid Use Disorder, Methamphetamine Abuse
Contingency Management for Drug Use: Does Age Matter?
The OVERALL AIM is to assess whether app-based incentives are effective for older adults and to quantify the associations between age and both the efficacy and take-up of app-based incentives.
- Conditions
- Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
- Trial name
- NCT05521854
- Testing
- DynamiCare app (app-based contingency management)
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Wake Forest University Health Sciences
Methamphetamine Use Disorder, Pregnancy
Transcranial Magnetic Stimulation for Methamphetamine Use Disorder During Pregnancy
The goal of this clinical trial is to learn whether transcranial magnetic stimulation, also called TMS, is a practical and acceptable treatment option for methamphetamine use disorder during pregnancy.
- Trial name
- NCT07849530
- Testing
- 4- Week Dual-Target Transcranial Magnetic Stimulation (TMS), Accelerated Dual-Target Transcranial Magnetic Stimulation (aTMS), Treatment as Usual (TAU)
- Volunteers
- 45 people
- Sponsor
- University of Utah
Methamphetamine Abuse
Theta Burst TMS for Treatment of Methamphetamine Use Disorder
This study is using Transcranial Magnetic Stimulation (TMS) to determine if interventional psychiatry treatment can help with the treatment of Methamphetamine Use Disorder.
- Trial name
- NCT06372288
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Carilion Clinic
Amphetamine Dependence
Dose Response of Mirtazapine to Methamphetamine Induced Interest, Mood Elevation and Reward
The primary purpose of this study is to determine if Mirtazapine will produce a decrease in interest in the drug, a decrease in mood elevation, and/or a decrease in reward when given before methamphetamine compared to placebo.
- Trial name
- NCT00600145
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia