Clinical trials: Methamphetamine Use
Stimulant Use Disorder
Mirtazapine for the Treatment of Methamphetamine Use in Opioid Use Disorder Patients Receiving Medication Assisted Treatment
This project will evaluate the ability of Mirtazapine (MZP), a pharmacologically unique medication with a growing body of evidence to support its efficacy and safety for the treatment of methamphetamine (MA) use among medication…
- Trial name
- MIRROM (NCT06323837)
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington State University
Burns, Acute Lung Injury
Amphetamine Induced Adult Respiratory Distress Syndrome
Methamphetamine and amphetamine has various cardiovascular and central nervous system effects. Long-term use is associated with many adverse health effects including cardiomyopathy, hemorrhagic, and ischemic stroke.
- Conditions
- Burns, Acute Lung Injury, Acute Respiratory Distress Syndrome, Methamphetamine Abuse
- Trial name
- NCT05611385
- Testing
- Difference in development of Acute Lung Injury in Amphetamine positive and negative patients
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Arrowhead Regional Medical Center
Contingency Managment, Methamphetamine Use Disorder
Implementing a Contingency Management Program Addressing Methamphetamine Use For and With the People of Hawaii
The goal of this clinical trial is to use contingency management (CM) as an intervention tool to address methamphetamine use. The main objectives are to: Gather effectiveness data on a pilot a CM program for participants in…
- Trial name
- NCT06532370
- Testing
- Contingency Managment
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Queen's Medical Center
Methamphetamine Use Disorder
A Study for the Risky Decision-making Deficits Among Methamphetamine Dependence Individuals and Treatment
The risky decision-making deficits is the core feature of the methamphetamine (MA) dependence. Our previous research found that MA dependents have network abnormalities such as decision-making and rewarding.
- Trial name
- NCT06279273
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Abuse
A Pilot Study of Repetitive Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorders
We propose a single-arm clinical trial, with historical controls as a comparison group for select outcomes. Subjects with MAUD will receive 16 sessions of dual-target theta burst stimulation to the DLPFC and MPFC over 4 weeks.
- Trial name
- NCT04883021
- Testing
- Dual Target Theta Burst Stimulation
- Where
- United States
- Sponsor
- University of New Mexico
Methamphetamine, Methamphetamine Abuse
Delivering Contingency Management in Outpatient Addiction Treatment
Methamphetamine misuse has become a growing concern in Alberta, creating a burden on the health care system. Further, individuals who use methamphetamine in Alberta exhibit significant difficulty remaining in treatment.
- Conditions
- Methamphetamine, Methamphetamine Abuse, Methamphetamine-dependence, Contingency Management
- Trial name
- PRISE (NCT04544124)
- Testing
- Contingency management
- Where
- 2 sites in Canada
- Volunteers
- 88 people
- Sponsor
- University of Calgary
Substance-Related Disorders
Disrupting SRFOH to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions
The study will evaluate the effectiveness of the Just Care for Families program in preventing Oregon Department of Human Services (ODHS)-involved parents in rural communities from escalating opioid and/or methamphetamine use and…
- Trial name
- NCT06560866
- Testing
- Just Care for Families
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Methamphetamine Use Disorder
Semaglutide for Treatment of People With Methamphetamine Use Disorder: the SHIFT Study
Methamphetamine use disorder is a major public health concern in Australia and globally. GLP-1 medications such as semaglutide (e.g.
- Trial name
- SHIFT (NCT07509112)
- Testing
- 12 weeks of weekly subcutaneous semaglutide injection
- Where
- 5 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Kirby Institute
Methamphetamine Use Disorder
Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV
The goal of this clinical trial is to learn whether it is possible to use intramuscular (IM) ketamine in combination with psychotherapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in publicly insured patients…
- Trial name
- KARE (NCT06538285)
- Testing
- Ketamine, Psychotherapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Nicky Mehtani, MD, MPH
Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers
Effectiveness of Stress Management Training Program For Expressed Emotions in Caregivers of Drug Induced Psychosis Patients Specially Methamphetamine
The main purpose of this study is to evaluate the effectiveness of a Stress Management Training (SMT) program in reducing stress levels among caregivers of individuals suffering from methamphetamine ("ice") addiction and…
- Conditions
- Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers, Stress Cause Expressed Emotion and Burden
- Trial name
- NCT07714642
- Testing
- O'Connor's (2003) Stress Management Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Amphetamine Use Disorders
Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorder
Repetitive transcranial magnetic stimulation (rTMS) was used to treat methamphetamine use disorder in previous studies, while the evidence-based protocols still required.
- Trial name
- NCT03736317
- Testing
- real mPFC cTBS, real dlPFC iTBS, real dlPFC iTBS + real mPFC cTBS
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Amphetamine Use Disorders
Closed-loop tTIS Targeted of the Nac as an Intervention for MUD Patients
Closed-loop transcranial temporal interference stimulation (tTIS) targeting the nucleus accumbens may modulate abnormal neural responses to drug-related cues in individuals with methamphetamine use disorder (MUD), thereby…
- Trial name
- NCT07802223
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Mental Health Center
HIV/AIDS, Adherence, Medication
Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users
Despite increasing knowledge about and use of PrEP nationally, HIV continues to have disproportionate impact among cisgender men and transgender persons who have sex with men and transgender persons (MSM/TG), with methamphetamine…
- Conditions
- HIV/AIDS, Adherence, Medication, Drug Use
- Trial name
- NCT03584282
- Testing
- Text Messaging, Peer Navigation
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Washington
Methamphetamine Use Disorder
The Effects of Suvorexant on Sleep, Stress, and Cue-reactivity in Methamphetamine Use Disorder
The purpose of this study is to determine the effects of SUVO on sleep, stress, and cue reactivity/craving and to evaluate the preliminary safety and side effects profile of suvorexant (SUVO)
- Trial name
- NCT05711862
- Testing
- suvorexant (SUVO)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The University of Texas Health Science Center, Houston
Methamphetamine Abuse
Mood and Decision-making in Methamphetamine Use Disorder
In this project, the investigators examine behavior and associated brain activity during explore-exploit decision-making tasks performed pre- and post-modulation of affective state using autobiographical memory recall.
- Trial name
- MDM-MUD (NCT06410196)
- Testing
- Mood modulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Methamphetamine Abuse
Digital Therapeutics Smartphone Application for Methamphetamine Use Disorder
One hundred participants were recruited and randomized into a digital therapeutics (DTx) group (n=52) and a treatment as usual (TAU) group (n=48).
- Trial name
- NCT05550493
- Testing
- Cognitive Behavioral Therapy, Counseling, Approach Bias Modification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Substance Use Disorders, Methamphetamine Abuse
Pharmacogenetics of Naltrexone for Stimulant Abuse
This investigation will be the first study assessing genetic modulation of naltrexone's NTX effects upon the abuse liability of a stimulant drug (methamphetamine).
- Trial name
- NCT03226223
- Testing
- Intranasal Methamphetamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- New York State Psychiatric Institute
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Addiction
The primary purpose of this study is to preliminarily determine if the use of psilocybin to promote abstinence from methamphetamine is feasible and well tolerated in populations such as those found in Northern Louisiana.
- Trial name
- NCT06899594
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kevin Murnane
Methamphetamine Abuse, Hiv
Methamphetamine, PrEP, and Intersectional Stigma Study
The goal of this clinical trail is to test the developed eMPrISe study in HIV-negative, adult, Latino men who have sex with men (MSM) who use non-injection substances.
- Conditions
- Methamphetamine Abuse, Hiv, Social Stigma
- Trial name
- eMPrISe (NCT05784467)
- Testing
- Methamphetamine, PrEP, and Intersectional Stigma (eMPrISe) study
- Volunteers
- 20 people
- Sponsor
- Arizona State University
Opioid-use Disorder, Cocaine Use Disorder
Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives
Combatting the rise of the opioid epidemic is a central challenge of U.S. health care policy. A promising approach for improving welfare and decreasing medical costs of people with substance abuse disorders is offering incentive…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use
- Trial name
- NCT04927143
- Testing
- App-Based Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wake Forest University Health Sciences