Clinical trials: Metoclopramide
Emesis, Postoperative, Maxillofacial Abnormalities
Effects of Antiemetic Agents in Orthognathic Surgery Patients
In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied.
- Trial name
- NCT06454825
- Testing
- Intravenous drug
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Headache, Migraine
Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department
Metoclopramide (Reglan) is a common agent used for relief of headaches in the emergency department (ED).In this study the investigators seek to explore another option for treatment of headaches in the ED, one that may be more…
- Trial name
- NCT02972502
- Testing
- Metoclopramide, Haloperidol, Normal Saline
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- OhioHealth
Akathisia
Prophylaxis Against Metoclopramide-Induced Akathisia
ABSTRACT Study Objective: To compare the effects of midazolam and diphenhydramine for the prevention of metoclopramide induced akathisia.
- Trial name
- NCT01051271
- Testing
- midazolam
- Volunteers
- 225 people
- Sponsor
- Pamukkale University
Probable Migraine, Migraine With Aura
Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department
Migraine headaches are a common problem for children. When treatment at home fails, children may benefit from intravenous treatment administered in a hospital setting like the Emergency Department.
- Conditions
- Probable Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- EDMigraine-4 (NCT01596166)
- Testing
- Ketorolac Tromethamine, Metoclopramide
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Trauma Injury
IV Injection of Metoclopramide With or Without Dexamethasone
Reflux and the aspiration of gastric contents have always been important focal points. Previous study stated that trauma is an important factor in aspiration pneumonia.
- Trial name
- NCT07343817
- Testing
- Dexamethasone, Ultrasonography assessment
- Volunteers
- 1 people
- Sponsor
- Ahmed Nassar Ibrahim Mohammed
Post-Traumatic Headache
Metoclopramide for Post Traumatic Headache
Nearly 1.5 million patients present to US emergency departments annually following head trauma. Headache is a frequent symptom of victims of head trauma.
- Trial name
- NCT03220958
- Testing
- Metoclopramide, Diphenhydramine, Normal saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
Gastroesophageal Reflux Disorder
Efficacy and Safety of Ondansetron Versus Metaclopromide Treatment in Infants With Gastro Oesophageal Reflux
This study aimed to fill the gaps by comparing the efficacy and safety of ondansetron versus metoclopramide for the control of gastroesophageal reflux disorder in children 1-12 months of age, presenting at the outdoor department…
- Trial name
- NCT06898268
- Testing
- Metoclopramide, Ondansetron
- Where
- Pakistan
- Volunteers
- 290 people
- Sponsor
- Muhammad Aamir Latif
Breastfeeding
Maxolon to Improve Breastmilk Supply in Diabetic Women: a Randomised Controlled Trial
Early use of oral maxalon can hasten and improve the establishment of breastfeeding in diabetic mothers after preterm and term deliveries.
- Trial name
- Maxalon (NCT00477776)
- Testing
- Metoclopramide (Maxolon)
- Where
- Singapore
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Cataract, Dexamethasone
Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery
Postoperative nausea and vomiting (PONV) is a common consequence of ambulatory surgery, affecting up to 80% of high-risk patients and 20-30% overall.
- Trial name
- NCT07086118
- Testing
- 0.9% normal saline, Metoclopramide 10mg, Dexamethasone
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Alexandria University
Acute Stroke, Aspiration Pneumonia
Metoclopramide vs Placebo for Prevention of Pneumonia in Acute Stroke
Pneumonia is a major cause of mortality and morbidity in patients with acute stroke fed via nasogastric tubes and may be because of vomiting and gastro-esophageal regurgitation.
- Trial name
- NCT04873297
- Testing
- Metoclopramide 10mg
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Nausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific
Drugs to Reduce the Side Effects of Chemotherapy
RATIONALE: Antiemetic drugs may help to reduce or prevent nausea and vomiting in patients treated with chemotherapy. It is not known whether receiving dexamethasone with granisetron is more effective than receiving dexamethasone…
- Trial name
- NCT00003213
- Testing
- dexamethasone, granisetron hydrochloride, metoclopramide hydrochloride
- Where
- 10 sites in Italy, Switzerland
- Volunteers
- 267 people
- Sponsor
- Swiss Cancer Institute
Trauma, Opioid Analgesic Adverse Reaction
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
Tramadol is widely used as analgesic in trauma patients. However, it causes side effects, most notably nausea and vomiting. This study aim to determine the role of prophylactic metoclopramide in preventing tramadol induced nausea…
- Trial name
- NCT03383315
- Testing
- Tramadol, Metoclopramide
- Where
- Malaysia
- Volunteers
- 191 people
- Sponsor
- University of Malaya
Aspiration Prophylaxis
Effect of Intravenous Metochlopramide Prophylaxis on Gastric Volume
Gastric fluid volume and pH in patients undergoing cesarean section are essential considerations for general anesthesia (GA). Increased gastric volume and low pH of gastric contents could predispose the risk of aspiration…
- Trial name
- NCT04609124
- Testing
- Abdominal ultrasound evaluation of antral area
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Assiut University
Poor Responders in IVF
Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients
Poor ovarian response population of ART are considered the biggest challenge for providers. Hitherto, no one protocol has been proven to be effect in this subgroup of IVF patients.
- Trial name
- NCT03560583
- Testing
- Metoclopramide
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Vomiting
The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics
This study investigates the effectiveness of combining vitamin B6 (pyridoxine) and metoclopramide compared to standard antiemetic treatments for managing nausea and vomiting.
- Trial name
- NCT06390787
- Testing
- Metoclopramide and Vitamin B6, Vitamin B6, Ondansetron
- Where
- Iraq
- Volunteers
- 250 people
- Sponsor
- University of Baghdad
Nausea, Vomiting
Olanzapine Plus Metoclopramide for the Prevention of Opioid-Induced Nausea and Vomiting
The goal of this clinical trial is to evaluate the efficacy and safety of olanzapine plus metoclopramide in preventing opioid-induced nausea and vomiting (OINV) in adult patients with advanced cancer who are initiating strong…
- Trial name
- NCT07208305
- Testing
- Olanzapine, Metoclopramide
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Affiliated Hospital of Qinghai University
Ileus Postoperative
The Effects of Combined Gum-chewing and Parenteral Metoclopramide on Post-operative Ileus
A delay in the return of bowel function is a common occurrence after abdominal surgeries.1 The goal of this study was to test the effect of the combined use of chewing a gum and administering metoclopramide intravenously on the…
- Trial name
- NCT05669781
- Testing
- Metoclopramide 10mg, Gum and metoclopramide, Gum
- Where
- Nigeria
- Volunteers
- 105 people
- Sponsor
- Ikechukwu Bartholomew Ulasi
Feeding Disorder, Nutrition Disorder
Use of Prokinetics in Early Enteral Feeding in Preterm Infants
Objective of this study are: 1) To determine if medication help extreme preterm infants to tolerate feeding better by reaching full feeding earlier.2) Out of two medication; which one is better for efficacy 1) Erythromycin 2)…
- Conditions
- Feeding Disorder, Nutrition Disorder, Infant,Premature
- Trial name
- NCT01569633
- Testing
- Metclopramide, Erythromycin
- Where
- United States
- Sponsor
- East Tennessee State University
Breastfeeding
Metoclopramide to Aid Establishment of Breastfeeding:a Randomised Controlled Trial
Hypothesis: Early use of oral metoclopramide can hasten and improve the establishment of lactogenesis II in mothers after preterm and term deliveries.
- Trial name
- NCT00264719
- Testing
- Metoclopramide (Maxolon)
- Where
- Singapore
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Drug Metabolism, Poor, CYP2D6-RELATED
Pharmacogenetic Factors and Side Effects of Metoclopramide and Diphenhydramine
Pharmacokinetic of Metoclopramide (MCP) in correlation to polymorphisms of CYP2D6 and Dopamine-D2-Receptor. Pharmacokinetic of Diphenhydramine (DPH) in correlation to polymorphisms of CYP2D6
- Trial name
- MalD (NCT01289938)
- Testing
- Diphenhydramine, Metoclopramide
- Where
- Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Matthias Schwab