Clinical trials: Microbial Composition
Caesarean Section;Stillbirth, Microbial Colonization
Lactobacillus Kefiri LKF01 (DSM32079) in Newborns Born by Caesarian Section
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life.
- Trial name
- NCT03154866
- Testing
- Lactobacillus kefiri LKF01 DSM32079
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Vitamin B 12 Deficiency
The Impact of Vitamin B12 Deficiency on Infant Gut Microbiota
Vitamin B12 plays important roles in DNA synthesis and neurological functions. Vitamin B12 deficiency is one of the most common micronutrient deficiencies and it has become increasingly more frequent in infants.
- Trial name
- NCT03365583
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marmara University
Microbial Composition
Optimization of Collection Methods for Studies of the Human Microbiota
Background: The human microbiota is the bacteria and other microbes found in and on the human body. Scientists study the microbiota because it is related to many health conditions.
- Trial name
- NCT03731702
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Delirium of Mixed Origin, Microbial Colonization
The Gut Microbiota and Delirium in the ICU
To investigate whether the composition of the gut microbiota is different in patients that develop delirium during critical illness as compared to patients who do not.
- Trial name
- GuMDel-ICU (NCT03328377)
- Testing
- Metagenomic analysis of gut microbiota
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Healthy
Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects
The purpose of the study is to evaluate the effects of arabinoxylan-oligosaccharides (AXOS) on the colonic metabolism and microbial composition, and to compare these effects with the reference prebiotic fructo-oligosaccharide…
- Trial name
- NCT00853034
- Testing
- FOS-IN, AXOS
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy Young Adults, Healthy Elderly
Pectin, Aging and Intestinal Barrier Function
The population is aging worldwide, which requires more attention to health needs and leads to a dramatic increase in health care costs. Prevention or delay of onset of disorders associated with aging is needed.
- Trial name
- NCT02376270
- Testing
- Pectin, Maltodextrin
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity (Disorder)
Effects of Gallotannins on the Gut Microbiome and How it Affects Inflammatory Markers Among Obese Individuals.
The goal of this clinical trial is to understand how gallotannin-rich (GT-rich) mangoes can reduce the inflammatory markers in obese individuals in vitro.
- Trial name
- NCT07505212
- Testing
- Gallotannin-rich mango, Lactiplantibacillus pentosus (probiotic), No Treatment Added
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Prairie View A&M University
Microbial Colonization
Effect of a Multi Strain Probiotic on the Gut Microbiota
Over recent years there has been a lot of research looking at how the bacteria in our gut affect our health. Changes to gut bacteria has been linked to several diseases.
- Trial name
- NCT04554641
- Testing
- Fasted breath samples, Daily Diary, Stool sample
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Functional Gut Clinic
Pilot Study
How Differences in the Composition of Microorganisms in the Soil Affect the Microorganisms in the Human Gut, Through the Vegetables That Grow in it: a Process Pilot Study With Healthy Participants
There are two objectives for this clinical trial. The first is to test whether, with the current logistics and study setup it is possible to perform the study well and see where there might be bottlenecks we couldn't predict.
- Trial name
- HUMANITAS (NCT07742319)
- Testing
- Low diversity vegetable smoothie, High diversity vegetable smoothie
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Healthy Adults
Galacto-oligosaccharides and Intestinal Activity
Dietary intake of galacto-oligosaccharides (GOS) may have beneficial effects on host health by affecting the microbiota composition and -activity.
- Trial name
- NCT04104360
- Testing
- Galacto-oligosaccharides, Maltodextrin
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Depression, LPS
Anaerobic Exercise and Mental Acuity
This is a randomized controlled trial to examine the effect of anaerobic activity (e.g., weight training) on gut microbiome metabolism and neurological health in healthy sedentary men.
- Conditions
- Depression, LPS, Mood
- Trial name
- NCT05850221
- Testing
- weight training
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Healthy
A Randomized, Comparative Study to Evaluate the Effect of RL3014A-DP0421 Mouthwash on the Oral Microbial Composition
The Laboratoires Pierre Fabre has on the market a product range of daily use mouthwash, all containing 0.05% of O-Cymen -5-ol, a broad-spectrum bactericide.
- Trial name
- NCT07685782
- Testing
- RL3014A - DP0421, CO3014AZ, CO3014AY
- Where
- Poland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Healthy
Randomized Study on Salt Intake and Energy Metabolism
To perform a randomized, double-blind clinical study on the effects of an increased salt intake on metabolic, cardiovascular and immunological parameters and the gut microbiota
- Trial name
- TS4 (NCT03024567)
- Testing
- Salt
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany