Clinical trials: Microdialysis
Staphylococcal Skin Infections, Streptococcal Infections
Evaluation of Penetration of Ceftobiprole Into Soft Tissue Determined by Microdialysis in Healthy Volunteers
The primary objective of this study is to measure the penetration of ceftobiprole into subcutaneous (s.c.) adipose tissue and skeletal muscle and to determine the concentration over time of ceftobiprole in these tissues and in…
- Trial name
- NCT01026740
- Testing
- Ceftobiprole
- Volunteers
- 15 people
- Sponsor
- Basilea Pharmaceutica
Traumatic Brain Injury
Copenhagen Head Injury Ciclosporin (CHIC) Study
This is an open label study on the pharmacokinetics and safety of ciclosporin in patients with severe traumatic brain injury, who require intensive care unit admission and monitoring of intracranial pressure via a ventricular…
- Trial name
- CHIC (NCT01825044)
- Testing
- NeuroSTAT 5 mg/kg/day, NeuroSTAT 10 mg/kg/day
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- NeuroVive Pharmaceutical AB
Kidney Diseases
Detecting Markers of Kidney Function With Intravenous Microdialysis
Patients will be invited to participate from an outpatient nephrology clinic at Hammersmith Hospital. They will have a microdialysis catheter inserted into a peripheral vein and connected to a sampling system.
- Trial name
- NCT03159806
- Testing
- Microdialysis sampling
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Accunea Ltd.
Healthy
Microdialysis and Pharmacokinetic Study of TR-701
The purpose of this study is to measure the penetration of TR-700 into subcutaneous adipose tissue and skeletal muscle after a single oral dose of 600 mg TR-701
- Trial name
- NCT00666601
- Testing
- TR-700 (active moiety), TR-701 (pro-drug)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Skin Infections, Bacterial
Retapamulin Microdialysis Feasibility Study
This feasibility study will allow for the determination of the in vivo recovery and time of dialysis to optimize a future thorough microdialysis study.
- Trial name
- NCT01812382
- Testing
- Retapamulin Microdialysis
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Transplant;Failure,Kidney
Real-time Monitoring of Kidney Grafts on Hypothermic Machine Perfusion
A significant number of deceased donor kidneys donated for transplantation are not used and are thrown away due to lack of ways of checking their condition and function before the operation.
- Trial name
- REMO-HYMAP (NCT04619732)
- Testing
- Monitoring biochemical concentrations during cold machine perfusion
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Accunea Ltd.