Clinical trials: Microplastics, active
Infertility, Microplastics Exposure
Fertility Impact of Microplastics - Advancing Countermeasures and Tracking
FERTIMPACT is a prospective clinical study based on the hypothesis that exposure to micro- and nanoplastics (MNPs) is associated with impaired reproductive function.
- Conditions
- Infertility, Microplastics Exposure, Fertility
- Trial name
- FERTIMPACT (NCT07562958)
- Volunteers
- 1,000 people
- Sponsor
- University of Kragujevac
Coronary Microvascular Dysfunction (CMD), Microplastic Exposure
Micro-nanoplastic Exposure and Coronary Microcirculatory Dysfunction as Well as Cardiovascular Outcomes
With strict quality control procedures applied throughout microplastic testing, this study will assess the association between baseline circulating micro-nanoplastic exposure and coronary microvascular dysfunction, as well as…
- Conditions
- Coronary Microvascular Dysfunction (CMD), Microplastic Exposure, Nanoplastics, MACE
- Trial name
- NCT07748767
- Testing
- micro-nanoplastic examination, Microvascular Function Examination
- Volunteers
- 184 people
- Sponsor
- Beijing Anzhen Hospital
Urolithiasis
Assessment of Urinary Microplastic Concentration in Patients With Urolithiasis: A Prospective Case-Control Study
This prospective observational case-control study aims to evaluate the presence and burden of microplastic particles in urine samples from patients with kidney and ureteral stones and to compare these findings with healthy…
- Trial name
- Microplastics (NCT07841834)
- Testing
- No Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Atopic Dermatitis
Prenatal Exposure to Emerging Contaminants and Children's Atopic Dermatitis
This prospective cohort study aims to investigate the association between prenatal blood levels of Emerging Contaminants and the five-year incidence of atopic dermatitis (AD) in offspring.
- Trial name
- PECCAD (NCT06316609)
- Testing
- Gestational Exposure to Emerging Contaminants (ECs)
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Children's Hospital of Fudan University
Crohns Disease, Pregnancy
Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation
The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as…
- Conditions
- Crohns Disease, Pregnancy, Inflammatory Bowel Disease
- Trial name
- PLANET (NCT06001450)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Microplastic and Nanoplastic Particle Burden in Peripheral Blood, Double-Filtration Plasmapheresis
Evaluating DFPP for Microplastic and PFAS Reduction
This prospective, non-interventional, within-subject paired biomarker study will evaluate whether circulating microplastic and nanoplastic-associated particle concentrations and PFAS concentrations in peripheral blood change…
- Trial name
- DFPP-MNP (NCT07658443)
- Testing
- Double-Filtration Plasmapheresis With the IN300 Apheresis Device
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 20 people
- Sponsor
- Proxima Health, Inc.
Gastric Cancers
The Association Between Microplastics and Macrogenomics and Metabolomics in Gastric Cancer
The aim of this study was to identify and quantify microplastics in blood, stool, and tumor surgical specimens from gastric cancer patients by analyzing the nature, type, and abundance of microplastics using laser direct infrared…
- Trial name
- NCT06856382
- Testing
- gastric cancer
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Dong Peng
Pancreatic Diseases, Pancreatic Neoplasms
Microplastics in Pancreas: Oncologic and Metabolic Impact
Microplastics and nanoplastics (MNPs) are emerging environmental contaminants that have been detected in several human tissues, raising concerns about their potential impact on human health.
- Trial name
- PAN-Plastic (NCT07486128)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Crohn Disease, Pediatric Inflammatory Bowel Diseases
Microplastic Analysis in Pediatric Inflammatory Bowel Disease
The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD.
- Conditions
- Crohn Disease, Pediatric Inflammatory Bowel Diseases, Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- MAP-IBD (NCT07141238)
- Testing
- Environmental microplastic exposure
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Lung Cancer
Investigation of MP Pollution in the Human Respiratory System and Its Relationship to Lung Cancer
This project will study and characterize Microplastic (MP) burden in the lungs of patients undergoing Bronchoalveolar Levage (BAL) in thoracic clinics at Moffitt.
- Trial name
- NCT06530615
- Testing
- Bronchoalveolar Lavage (BAL) during Bronchoscopy
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Artificial Turf, Athletic Performance and Injury Risk
Analysis of New Materials and Artificial Turf Products: Influence and Impact on Athlete Performance and Perception
This request pertains to a series of related projects on a common theme. Specifically, this set of projects aims to analyze the impact of new alternatives in materials and structures of artificial turf on athlete performance and…
- Conditions
- Artificial Turf, Athletic Performance and Injury Risk, Physical Fitness, Sports Equipment
- Trial name
- ANMATT (NCT06939218)
- Testing
- Countermovement Jump (CMJ), Repeated Jump Test, Repeated Sprint Ability (RSA) Test
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
ST-elevation Myocardial Infarction (STEMI), Microplastics
Microplastics and Nanoplastics (MNPs) in Patients With ST-elevation Myocardial Infarction (STEMI)
Air pollution and microplastics pose major public health threats. Emerging data have shown that micro- and nanoplastics (MNPs) are ubiquitous environmental pollutants accumulating in human tissues, triggering inflammation and…
- Conditions
- ST-elevation Myocardial Infarction (STEMI), Microplastics, Nanoplastics, Pollution Exposure
- Trial name
- STEMI-Plastics (NCT06965023)
- Where
- 10 sites in Italy
- Volunteers
- 130 people
- Sponsor
- Azienda Ospedaliera "Sant'Andrea"
Intracerebral Hemorrhage, Brain Hematoma
Microplastics in Brain Hematomas and Neurological Outcomes After Intracerebral Hemorrhage
This observational study investigates the presence of micro- and nanoplastics in surgically removed intracerebral hematomas and their association with neurological outcomes in patients with spontaneous intracerebral hemorrhage.
- Trial name
- PARTENOPE (NCT07580326)
- Testing
- Observational Analysis
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Campania Luigi Vanvitelli
Gastric Carcinoma, Gastritis Chronic
Association Between Microplastic Exposure and the Pathological Progression of Gastric Carcinogenesis
The objective of this clinical trial is to explore the correlation between the level of microplastic exposure and the risk of gastric mucosal carcinogenesis, and to evaluate the strength of its effect as an independent risk…
- Conditions
- Gastric Carcinoma, Gastritis Chronic, Intestinal Metaplasia, Gastric Precancerous Lesions
- Trial name
- NCT07542652
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Yongquan Shi
Bronchopulmonary Dysplasia
Preliminary Study on Microplastics Deposition in Ventilator Circuit and the Risk of Bronchopulmonary Dysplasia in Premature Infants
In this study, the premature infants with gestational age less than 30 weeks were taken as the object, and the deposition characteristics of microplastics in ventilator circuit and its correlation with the risk of…
- Trial name
- Microplastics (NCT07848646)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiyi Li
Female Infertility, Environmental Exposure
Detection of Microplastics in Human Granulosa Cells and in the Follicular Fluid of Women Undergoing ICSI Treatment
Plastic products have been used ubiquitously in the modern world for many decades - for example as packaging materials, textile fibers or molded parts.
- Trial name
- MP2021 (NCT05179993)
- Testing
- Microplastics
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Periodontal Diseases, Periodontitis
Detection of Microplastics in Patients With Periodontitis
Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system.
- Trial name
- micropl_perio (NCT07231198)
- Volunteers
- 25 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Healthy Adult Participants
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
The goal of this observational study is to evaluate the feasibility and usability of at-home urine sample collection, preparation, and smartphone imaging using the EcoExposure™ platform in adults.
- Trial name
- OMNU (NCT07775495)
- Where
- 51 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ecotera Health LLC
Obesity and Overweight
Identification of Microplastics in Liver, Stomach, Blood, and Feces of Obese Patients and Their Association Analysis with Macrogenomics and Metabolomics.
The aim of this study was to identify and quantify microplastics in the stomach, liver, feces, and blood of obese patients to be treated with bariatric surgery by using a variety of advanced analytical techniques to explore the…
- Trial name
- NCT06826586
- Testing
- Measuring the microplastics
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Microplastic Exposure
Microplastic Exposure From Clear Aligner Wear (MPE)
An observational longitudinal study measuring microplastic exposure and physiologic uptake in orthodontic patients receiving clear aligner treatment.
- Trial name
- MPE (NCT06934603)
- Testing
- Clear Aligner Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill