Clinical trials: Microscopic Colitis
Microscopic Colitis
A Study to Investigate the Efficacy and Safety of SAR444336 in Adults With Microscopic Colitis in Clinical Remission
This is a parallel, placebo-controlled, multicenter, randomized, double-blind, Phase 2, proof of concept study. The study aims to evaluate the efficacy and safety of SAR444336 in adult participants with microscopic colitis.
- Trial name
- NCT07156175
- Testing
- SAR444336
- Where
- 24 sites in Belgium, Denmark and 7 more
- Volunteers
- 54 people
- Sponsor
- Sanofi
Microscopic Colitis
Efficacy and Safety of Budesonide MMX® vs. Budesonide CR for Induction of Remission in Microscopic Colitis
The purpose of this research study is to compare how well two formulations of budesonide (budesonide MMX [Cortiment] and budesonide CR [Entocort]) work for treating patients with microscopic colitis.
- Trial name
- NCT05915104
- Testing
- Budesonide MMX®, Budesonide controlled ileal release (CR) capsules
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Calgary
Chronic Diarrhea, Microscopic Colitis
Chronic Diarrhea Owing to Underlying Microscopic Colitis
The goal of this observational study is to search for accurate diagnoses for patients with chronic diarrhea and assess the prevalence of microscopic colitis.
- Trial name
- NCT06530836
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Enabling Microbiomics- Driven Personalized Nutrition
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Celiac Disease, Diarrhea
- Trial name
- EMPOWER (NCT06657001)
- Where
- United States
- Volunteers
- 4,001 people
- Sponsor
- Mayo Clinic
Ulcerative Colitis, Crohn Disease
Systems Biology of Gastrointestinal and Related Diseases
This is a longitudinal observational study on patients with gastrointestinal and related disease. The study will be conducted for at least 10 years, following each participant over time, as they either go through relapses and…
- Conditions
- Ulcerative Colitis, Crohn Disease, Obesity, Colon Polyp
- Trial name
- NCT05579444
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Viome
Microscopic Colitis, Colorectal Cancer
Mucosa Adherent Intestinal Microbiome in Microscopic Colitis and Colorectal Cancer
Microscopic colitis (MC) is an inflammatory bowel disease characterized by chronic non-bloody watery diarrhoea and a macroscopically normal colonic mucosa upon endoscopic exploration (colonoscopy).
- Conditions
- Microscopic Colitis, Colorectal Cancer, Colon Adenoma
- Trial name
- CMBACT (NCT06172647)
- Testing
- Colonoscopy
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Mutua de Terrassa
Microscopic Colitis
External Validation of a Microscopic Colitis Clinical Scoring System in Patients With Chronic Watery Diarrhoea
Chronic watery diarrhoea is a very common problem in the population and most of these patients will be referred for colonoscopy.
- Trial name
- NCT06031064
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Mutua de Terrassa
Microscopic Colitis
Faecal Microbiota Transplantation for Microscopic Colitis
A pilot study investigating if orally administrated faecal microbiota transplantation capsules have the potential to treat active microscopic colitis.
- Trial name
- NCT05998174
- Testing
- Faecal Microbiota Transplantation
- Volunteers
- 20 people
- Sponsor
- Hvidovre University Hospital
Microscopic Colitis
Modulation of Intestinal Barrier Function and Inflammation Via Butyrate-promoting Dietary Fibre
This study examines how a fermentable dietary fibre known to promote butyrate production impacts intestinal barrier function, intestinal microbiota, intestinal inflammation, and gastrointestinal symptoms in patients with…
- Trial name
- NCT05058131
- Testing
- Dietary fibre
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Örebro University, Sweden
Colitis, Microscopic
Identification/Characterization of Changes in Microscopic Colitis
The goal of this study is to establish a prospective observational cohort of adult patients with microscopic colitis and collect clinical information and specimens over the course of their treatment.
- Trial name
- NCT03063957
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Massachusetts General Hospital
Microscopic Colitis
Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis
This is an open label study looking at rifaximin therapy for the treatment of microscopic (collagenous or lymphocytic) colitis.
- Trial name
- NCT04043897
- Testing
- Rifaximin 550mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Eugene F Yen, MD
Colitis, Microscopic
Risk Factors for Microscopic Colitis
Microscopic colitis is a common cause of watery diarrhea, particularly in the elderly. Although the incidence is comparable to ulcerative colitis and Crohn's disease, the etiology is unknown.
- Trial name
- NCT02699333
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- University of North Carolina, Chapel Hill
Incomplete Microscopic Colitis
Budesonide for Induction of Remission in Incomplete Microscopic Colitis
The purpose of this study is to demonstrate the efficacy of budesonide for the treatment of active incomplete microscopic colitis.
- Trial name
- NCT02142634
- Testing
- Budesonide granules 9 mg
- Where
- 2 sites in Germany, Sweden
- Volunteers
- 44 people
- Sponsor
- Dr. Falk Pharma GmbH
Microscopic Colitis
Faecal Microbiota Transplantation in Patients With Microscopic Colitis
Microscopic colitis (MC) is a disease with chronic inflammation of the colon that is mostly diagnosed in middle-aged or elderly women. Patients suffer from chronic watery diarrhoea, abdominal pain and weight loss.
- Trial name
- NCT03275467
- Testing
- Faecal microbiota transfer (FMT)
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Faecal Microbiota Transplantation, Crohn Disease
FMT in Inflammatory Bowel Disease
This is a prospective observational cohort study, over 52 weeks, evaluating the the use of faecal microbiota transplantation amongst patients with Inflammatory Bowel Disease and Microscopic Colitis
- Conditions
- Faecal Microbiota Transplantation, Crohn Disease, Ulcerative Colitis, Microscopic Colitis
- Trial name
- NCT03477032
- Testing
- Faecal Microbiota Transplantation
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- St Vincent's Hospital Melbourne
Collagenous Colitis
Rifaximin-treatment of Collagenous Colitis
The hypothesis of this study is that an altered gut microbiota is a contributory factor in initiating an inflammatory process in the colonic mucosa leading to collagenous colitis.
- Trial name
- XiCoCo (NCT03658993)
- Testing
- Rifaximin 550 MG
- Volunteers
- 50 people
- Sponsor
- Bonderup, Ole K., M.D.
Microscopic Colitis, Collagenous Colitis
Case-Control Study to Identify Risk Factors for Microscopic Colitis
The purpose of the study is to assess among others environmental and hygiene-related risk factors for microscopic colitis (MC), a common diarrheal disease.
- Conditions
- Microscopic Colitis, Collagenous Colitis, Lymphocytic Colitis
- Trial name
- NCT01928667
- Testing
- Whole saliva sample
- Where
- Netherlands
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Microscopic Colitis
Ussing Experiments to Evaluate the Role of Medication-induced Microscopic Colitis
Medication use, especially NSAIDs and PPIs, prior to diagnosis is considered a risk factor for MC development. However, the exact pathophysiological mechanism is unclear.
- Trial name
- NCT02303132
- Testing
- Ussing experiment
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chronic Diarrhoea, Lymphocytic Colitis
Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis
The purpose of this study is to determine whether chromoendoscopy using Indigo-Carmine dye spray is useful in diagnosing microscopic colitis among patients undergoing colonoscopy due to chronic watery diarrhea.
- Conditions
- Chronic Diarrhoea, Lymphocytic Colitis, Collagenous Colitis
- Trial name
- NCT01504048
- Testing
- Colonoscopy with Indigo-Carmine Chromoendoscopy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Colitis
Treatment of Microscopic Colitis
The study compares the effect of Budesonide, Bismuth and fiber in patients with microscopic colitis
- Trial name
- NCT00184171
- Testing
- Budesonide, Bismuth, Fiber
- Where
- 9 sites in Norway
- Volunteers
- 105 people
- Sponsor
- Norwegian University of Science and Technology