Clinical trials: Microtia, Congenital
Microtia, Microtia, Congenital
Study of Analgesic Efficacy of Nerve Blocks on Otoplastic Surgery
Background: Children with microtia complain of severe postoperative pain during early postoperative days after rib cartilage harvest for auricular reconstruction.
- Trial name
- NCT04192708
- Testing
- intercostal nerve block under direct vision, intercostal nerve block under ultrasound guidance, paravertebral block under ultrasound guidance
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Microtia, Alcohol Dependence
Nitrate Modulates Cognitive Impairment Via Oral Microbiota.
Alcohol use is increasingly prevalent in modern society and is known to cause cognitive impairment and dysregulation of inflammatory responses.
- Trial name
- NCT05963659
- Testing
- nitrate-rich beetroot juice, nitrate-depleted beetroot juice
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Sixth Hospital
Microtia, Dysbiosis
Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and…
- Conditions
- Microtia, Dysbiosis, Alcohol Drinking, HIV Infections
- Trial name
- META HIV CVD (NCT05288790)
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Vanderbilt University Medical Center
Craniofacial Microsomia, Hemifacial Microsomia
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
This study is a multi-center, longitudinal cohort study of 125 infants with craniofacial microsomia (CFM) and 100 infants without craniofacial anomalies.
- Conditions
- Craniofacial Microsomia, Hemifacial Microsomia, Oculo-Auriculo-Vertebral-Syndrome, Goldenhar Syndrome
- Trial name
- CLOCK (NCT02224677)
- Where
- 5 sites in United States
- Volunteers
- 417 people
- Sponsor
- Seattle Children's Hospital
Obesity, Microtia
Akkermansia and Weight Maintenance
Obesity and related disorders such as type 2 diabetes are a worldwide diet-related problem. As such new treatment options are constantly being developed.
- Conditions
- Obesity, Microtia, Metabolic Syndrome, Weight Loss
- Trial name
- Amansia (NCT05417360)
- Testing
- Akkermansia muciniphila
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Microtia, Congenital, Microtia
Rib Microtia and the Erector Spinae Plane (ESP) Block
The erector spinae plane block is a novel regional anesthetic technique that allows for analgesia of the thorax and abdomen with a peripheral nerve block.
- Conditions
- Microtia, Congenital, Microtia, Anesthesia, Local, Anesthesia
- Trial name
- NCT03729427
- Testing
- Erector Spinae Plane Block
- Where
- United States
- Sponsor
- Stanford University
Congenital Microtia
Application and Effectiveness of the Perioperative Position Management Based on the ADDIE Model in Patients With Congenital Microtia
Aims and objectives: To evaluate the clinical application and effectiveness of a perioperative position management program constructed using the ADDIE model for patients with congenital microtia.
- Trial name
- NCT06569927
- Testing
- Utilization of a perioperative position management protocol for congenital microtia patients based on the ADDIE model.
- Where
- China
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Microtia, Outcome Assessment
Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery
Eligible patients will be admitted from the outpatient clinic to complete the relevant examinations after admission（Preoperative routine examination and chest CT）.
- Conditions
- Microtia, Outcome Assessment, RCT, Surgery Related Complications Rate
- Trial name
- NCT06763991
- Testing
- Two-stage connection, One-stage connection
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Sichuan Provincial People's Hospital
Insulin Sensitivity, Glucose Metabolism Disorders
Bisphenol A and Muscle Insulin Sensitivity
This study examine oral bisphenol A consumption on muscle insulin sensitivity and hepatic glucose suppression. Half of the participants will receive a diet plus BPA and the other half will receive a diet plus no bisphenol A.
- Conditions
- Insulin Sensitivity, Glucose Metabolism Disorders, Microtia
- Trial name
- NCT03771066
- Testing
- bisphenol A
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Microtia, Congenital, Auricular Reconstruction
Social Perception of Microtia
Rationale: Microtia is a congenital craniofacial condition characterized by the underdevelopment of the external ear. Children with microtia become aware of their deformity at a young age, and this awareness intensifies in…
- Trial name
- NCT07721805
- Where
- Netherlands
- Volunteers
- 1,271 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Overweight, Microtia
Demonstration of the Prebiotic-like Effects of Camu-camu Consumption Against Obesity-related Disorders in Humans
Previous work of the investigators demonstrated the anti-obesity and anti-steatosis potential of the Amazonian fruit camu-camu (CC) in a mouse model of diet-induced obesity [1].
- Conditions
- Overweight, Microtia, Endotoxemia, Metabolic Syndrome
- Trial name
- NCT04130321
- Testing
- Camu camu
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Laval University
Inflammatory Bowel Diseases, Clostridium Difficile Infections
Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD Patients
The goal of this research is to compare alterations of gut microbiota and fecal metabolomics alterations between inflammatory bowel disease patients infected with or without Clostridioides difficile.
- Conditions
- Inflammatory Bowel Diseases, Clostridium Difficile Infections, Microtia
- Trial name
- NCT05714566
- Testing
- Clostridioides difficile toxin detection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Microtia
Auricular Reconstruction in Microtia by Medpor Implant Following Tissue Expansion
The study involves patients with microtia of certain criteria will undergo tissue expansion by silicone bags in the postauricular region then Medpor implants will be applied undercover of the expanded skin for reconstruction of…
- Trial name
- NCT05068362
- Testing
- Auricular reconstruction
- Where
- Egypt
- Volunteers
- 3 people
- Sponsor
- Assiut University