Clinical trials: Microvascular Resistance
Vascular Stiffness, Insulin Sensitivity
Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults
The investigators are studying the effects of Hyperglycemia on vascular function and insulin sensitivity on healthy adults
- Trial name
- EJB050 (NCT03520569)
- Testing
- Octreotide, Insulin, Dextrose 20% solution
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Metabolic Syndrome, Coronary Microvascular Dysfunction
Vericiguat in Patients With Metabolic Syndrome and Coronary Vascular Dysfunction
Coronary vascular dysfunction is one of the "final common pathways" for the impact of multiple cardiovascular risk factors. The investigators will conduct a randomized, double-blind placebo-controlled study in individuals with…
- Trial name
- NCT05711719
- Testing
- Vericiguat
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins University
Psoriasis, Metabolic Syndrome
Effects of TNF-alpha Antagonism (Etanercept) in Patients With the Metabolic Syndrome and Psoriasis
People with psoriasis have significantly higher rates of obesity, diabetes, heart failure and high blood pressure than the general public.
- Conditions
- Psoriasis, Metabolic Syndrome, Hyperlipidemia, Obesity
- Trial name
- NCT00477191
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Massachusetts General Hospital
Multi Vessel Coronary Artery Disease, STEMI
Assessing Microvascular Resistance Via IMR To Predict Cumulative Outcome in STEMI Patients Undergoing Primary PCI
The purpose of this study is to assess whether the Index of Microcirculatory Resistance (IMR) can be considered a prognostic predictor for the occurrence of events at one year of follow up after primary Percutaneous Coronary…
- Trial name
- AMICRO (NCT02325973)
- Testing
- PressureWire Certus guidewire
- Where
- 14 sites in Italy
- Volunteers
- 242 people
- Sponsor
- Abbott Medical Devices
Acute Coronary Syndrome (ACS), High On-treatment Platelet Reactivity (HTPR)
The Effect of IV Cangrelor and Oral Ticagrelor Study
Major heart attacks are caused by a number of factors, the two major of which are furring up of a coronary artery with atheroma and then sudden clot formation on this area leading to a blockage and interruption of blood flow.
- Conditions
- Acute Coronary Syndrome (ACS), High On-treatment Platelet Reactivity (HTPR), Microvascular Obstruction (MVO), ST-segment Elevation Myocardial Infarction (STEMI)
- Trial name
- NCT02733341
- Testing
- Cangrelor, Ticagrelor
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust