Clinical trials: Middle Aged Patients
Hypotension
Median Sevoflurane Concentration for Hypotension Between Young and Elderlypatients: Adaptive Clinical Trial
Two arms: elder group, young group. Dixon's up and down adaptive methodology for ED50. Executed after Anesthesia induction for 10min without touching the patient after starting mechanical ventilation.
- Trial name
- NCT03595319
- Testing
- Sevoflurane
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Brasilia University Hospital
Hormone Deficiency
Outcomes of Adipose Derived Mesenchymal Stem Cells on Sexual Hormone Deficiency
The purpose of this study is to evaluate the safety and effectiveness of adipose derived mesenchymal stem cells (AD-MSCs) therapy on sexual hormone deficiency in the middle-aged patients
- Trial name
- MSCSHD (NCT03346967)
- Testing
- adipose-derived mesenchymal stem cells
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Low Back Pain
Comparative Analysis of DS and NMT on Pelvic Inclination in Early Middle-Aged Patients With Radicular Low Back Pain
Radicular low back pain (RLBP) is a common and debilitating condition characterized by nerve root irritation or compression, often resulting in altered biomechanics, muscular imbalances, and postural deviations such as anterior…
- Trial name
- NCT06997640
- Testing
- Dynamic Stretching Protocol, Neural Mobilization Technique Protoco
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Superior University
Middle Aged Patients, General Anesthesia
Minimum Alveolar Concentration of Sevoflurane With Nitrous Oxide Inducing Isoelectric EEG
In order to investigate the effect of a combination effect of sevoflurane and nitrous oxide on cerebral electrical activity, the investigators determined the MAC of sevoflurane combined with nitrous oxide inducing isoelectric…
- Trial name
- NCT01705743
- Testing
- Sevoflurane+Nitrous oxide, Sevoflurane
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Huazhong University of Science and Technology
Neck Pain, Cervical Pain
The Effect of Smartphone Use Duration in Patients With Chronic Mechanical Neck Pain.
PURPOSE: The purpose of this study is to investigate the effects of smartphone usage duration on neck pain and sense of position as well as Deep Cervical Flexor (DCF) fatigue in young and middle aged patients with chronic…
- Trial name
- NCT03745469
- Testing
- Smartphone
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Aliaa Rehan Youssef
Effect of Age on Mortality, ICU Mortality
Impact of Age on Mortality in Critically Ill Adult Patients in Nepal- a Single Center Retrospective Study of 5 Years.
Rationale: Age is often considered a strong factor that determines the outcomes in critically ill patients. In a resource limited low middle income country (LMIC) like Nepal, the age factor is often considered when making…
- Conditions
- Effect of Age on Mortality, ICU Mortality, Age
- Trial name
- NCT06888206
- Where
- Nepal
- Volunteers
- 8,189 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Diabetes Mellitus, Type 2, Depression
Minimal Psychological Intervention in Diabetes Patients
The purpose of this study is to determine whether the telephone-delivered Minimal Psychological Intervention (MPI) could improve diabetes' depressive symptom and diabetes-related immediately , as well as HbA1c level in the…
- Trial name
- NCT02473081
- Testing
- Minimal psychological intervention, Usual care
- Volunteers
- 182 people
- Sponsor
- National Cheng-Kung University Hospital
Depressive Disorder, Major, Adult Attention Deficit Hyperactivity Disorder
Clinical and Suicidal Features of Urban, Turkish Middle Age Depressive Patients With Comorbid ADHD
In the presence of attention deficit hyperactivity disorder (ADHD) together with additional psychiatric diseases, the treatment process and prognosis of both ADHD and psychiatric comorbidity are adversely affected.
- Conditions
- Depressive Disorder, Major, Adult Attention Deficit Hyperactivity Disorder, Suicide
- Trial name
- NCT03721588
- Testing
- Clinical interviews, psychometric scales were applied.
- Volunteers
- 96 people
- Sponsor
- Bozyaka Training and Research Hospital
PCIA, Frailty
Impact of Frailty on Nalbuphine Dose for Postoperative Analgesia in Elderly Patients Undergoing Laparoscopic GI Surgery
This study aims to investigate the ED50 and ED95 of nalbuphine combined with dexmedetomidine in patient-controlled intravenous analgesia (PCIA) for elderly patients with different degrees of frailty, as well as their analgesic…
- Conditions
- PCIA, Frailty, Laparoscopic Gastrointestinal Surgery
- Trial name
- NCT06953570
- Volunteers
- 120 people
- Sponsor
- Yongtao Sun
Heart Failure
Balance and Executive Function in Middle-age and Older Patients With Heart Failure in Post-Acute Care Program
This trial is a single-center clinical trial in Taiwan with an expected enrollment of 60 people in Taiwan. The purpose of this trial is to compare the performance of middle-aged and elderly patients with subacute heart failure…
- Trial name
- NCT06463496
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Chia-Jung
Psoriasis
Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients
The purpose of this study is to determine the safety and efficacy of voclosporin in patients with plaque psoriasis.
- Trial name
- ESSENCE (NCT00408187)
- Testing
- voclosporin, Ciclosporin
- Where
- 49 sites in Canada, Germany and 1 more
- Volunteers
- 642 people
- Sponsor
- Aurinia Pharmaceuticals Inc.
Depression
Preventing the Return of Depression in Elderly Patients
The purpose of this study is to compare the effectiveness of two doses of nortriptyline in elderly patients whose depression returned after stopping treatment. Nortriptyline is an antidepressant.
- Trial name
- NCT00000377
- Testing
- Nortriptyline
- Sponsor
- University of Pittsburgh
Early Onset Alzheimer Disease, Alzheimer Disease
Sleep Apnea in Early to Mid-Stage Alzheimer's Disease
Obstructive sleep apnea (OSA) is much more common in the elderly than in the young; the latest studies show prevalence between 45% and 62% in individuals over 60.
- Conditions
- Early Onset Alzheimer Disease, Alzheimer Disease, Obstructive Sleep Apnea Syndromes
- Trial name
- AZAP (NCT01400542)
- Testing
- CPAP Treatment, No treatment
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Quality of Life, Health Care Acceptability
Quality of Care and Welfare Services for Disabled Middle Older Adults in Iran Lebanon
The findings of this research will be a basis for improving the quality of care and welfare services for the disabled middle-aged and older people in Iran and Lebanon using the SERVQUAL model.
- Conditions
- Quality of Life, Health Care Acceptability, Disabilities Mental
- Trial name
- ServQual (NCT05876819)
- Where
- Iran
- Volunteers
- 86 people
- Sponsor
- Shiraz University of Medical Sciences
Hip Fractures
Hip Fracture in Individuals Under 60 Years of Age
This study prospectively analyses and describes a cohort of non-elderly hip fracture patients at four orthopaedic departments in two Scandinavian countries regarding epidemiology, treatment, Patient Reported Outcome Measures…
- Trial name
- HFU-60 (NCT03848195)
- Where
- 4 sites in Denmark, Sweden
- Volunteers
- 218 people
- Sponsor
- Lund University
Chronic Pain
Escoge Salud (Choose Health): a Chronic Pain Self-Management Program in Middle to Older Age Hispanic Americans
The purpose of this study is to evaluate patient satisfaction and health status before and after a 6-week established self-management training program for middle to older age Hispanic Americans living with chronic musculoskeletal…
- Trial name
- NCT04554576
- Testing
- Chronic Disease Self-Management Program (CDSMP) for chronic pain in Spanish, Remote feedback active group, Remote feedback control group
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kaiser Permanente
Knee Pain Chronic
Arthroscopic Versus Conservative Treatment of Degenerative Meniscal Tear in Middle Aged Patients in Regard to Pain & Knee Function
The study is prospective comparative study, conducted in Erbil teaching hospital on 60 patients, their age ranging between 40 and 60 years.
- Trial name
- NCT04313569
- Testing
- Arthroscopic menisctomy
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Hawler Medical University
Cognitive Disorders
EGb 761® (Tanakan®) Effectiveness in the Treatment of Patients of Middle Age and Younger With Psycho-emotional Symptoms, Added to Cognitive Disorders
The purpose of this study is to determine the effectiveness of EGb 761® (Tanakan®) in Russian patients of middle age and younger, suffering from psycho-emotional symptoms added to cognitive disorders based on the improvement of…
- Trial name
- TAYPES (NCT02321475)
- Testing
- EGb761®
- Where
- 2 sites in Russia
- Volunteers
- 54 people
- Sponsor
- Ipsen
Frailty, Anesthesia Induction
ED50 of Remimazolam for Anesthesia Induction in Frail Elderly Patients
This study aimed to determine the median effective dose (ED50) of remimazolam for loss of consciousness (LOC) in elderly and frail elderly patients using the Dixon up-and-down method, while utilizing a novel Respiratory Volume…
- Trial name
- NCT07467603
- Testing
- Remimazolam Tosilate
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Hospital of Hebei Medical University
Tooth Wear, Attrition
Prevalence of Tooth Wear and Its Association with Oral Health-related Quality of Life
The aim of this study is to detect the prevalence of tooth wear (All forms of cumulative surface loss of mineralized tooth substance loss due to physical and chemico-mechanical process according to the definition of the European…
- Conditions
- Tooth Wear, Attrition, Erosion
- Trial name
- NCT06665191
- Testing
- No Intervention: Observational study for prevalence of dental wear and its association with quality of life
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Cairo University