Clinical trials: Middle Cerebral Artery Infarction
Acute Ischaemic Middle Cerebral Artery Stroke
A Study to Evaluate the Efficacy and Safety of Piracetam on Aphasia After Acute Ischemic Cerebral Artery Stroke
The aim of this study was to confirm the efficacy of piracetam after 12 weeks of treatment on the aphasic status of subjects suffering from aphasia after acute ischemic middle cerebral artery stroke and having received their…
- Trial name
- NCT01883011
- Testing
- Piracetam
- Where
- 44 sites in Argentina, Austria and 13 more
- Volunteers
- 571 people
- Sponsor
- UCB S.A. - Pharma Sector
Stroke, Middle Cerebral Artery Stroke
Dual-Task Training With Different Priority Instructional Sets on the Gait Parameters in Patients With Chronic Stroke
Balance is controlled through a complex process involving sensory, visual, vestibular and cerebral functioning which get affected by various neurological disorders such as in stroke.
- Conditions
- Stroke, Middle Cerebral Artery Stroke, Chronic Stroke
- Trial name
- NCT03752788
- Testing
- Dual-task Training Fixed Priority, Dual-task Training Variable Priority
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
Infarction, Middle Cerebral Artery, Ischemic Stroke,
Implantation of Olfactory Ensheathing Cells (OECs)
Recruited patients should receive the endoscopic surgery for picking the olfactory mucosa 1 to 2 months before transplantation. The Olfactory Ensheathing Cells (OECs) will be cultured and expanded under the rule of GTP.
- Conditions
- Infarction, Middle Cerebral Artery, Ischemic Stroke,, Stroke With Hemiparesis,, Thromboembolic Stroke.
- Trial name
- OECs (NCT01327768)
- Testing
- Olfactory ensheathing cells
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- China Medical University Hospital
High Resolution Vessel Wall Imaging, Recurrent Stroke
Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients
The epidemiology of TOAST classification in Asian patients seems to differ due to the higher rates of large-artery atherosclerosis.
- Conditions
- High Resolution Vessel Wall Imaging, Recurrent Stroke, Stroke, Mechanism, Atheroscleroses, Intracranial
- Trial name
- NCT06404242
- Where
- Vietnam
- Volunteers
- 75 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Middle Cerebral Artery Occlusion With Cerebral Infarction
The AGAINST Protocol: Augmentative Craniotomy in Stroke
Malignant Middle Cerebral Artery (MCA) infarction is a term used for the severe clinical and neurological hemispheric syndrome caused by ischemic occlusion of the proximal tract of MCA and it is observed in near the 10% of all…
- Trial name
- AGAINST (NCT05860855)
- Testing
- Augmentative craniotomy, Decompressive craniotomy
- Volunteers
- 70 people
- Sponsor
- University of Roma La Sapienza
Ischemic Stroke, MCA Infarction
Intraarterial Stem Cells in Subacute Ischemic Stroke
Stroke is a leading cause of morbidity and mortality.Acute ischemia causes irreversible damage to neurons and glial cells, leading to functional deficits and chronic sequelae with variable degrees of spontaneous recovery of…
- Trial name
- NCT03080571
- Testing
- autologous BMMNC stem cells, standard care
- Volunteers
- 20 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Stroke, Acute
aICP Measurement in Patients With Cerebral Artery Infarction / aICP MCA Infarction
Space-occupying, malignant middle cerebral artery (M-MCA) infarctions are still one of the most devastating forms of ischemic stroke, with a mortality of up to 80% in untreated patients.
- Trial name
- aICPStroke (NCT03641963)
- Testing
- Vittamed 205 Non-invasive intracranial pressure (ICP) meter
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Kantonsspital Aarau
Stroke, Acute, Stroke, Ischemic
Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial
The objective of the MEDIS study is to determine if subjects experiencing an Acute Ischaemic Stroke due to large vessel occlusion, treated with IV tPA combined with the MED procedure have a greater likelihood of recanalisation…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Infarction, Middle Cerebral Artery, Strokes Thrombotic
- Trial name
- MEDIS (NCT03098732)
- Testing
- Magnetically Enhanced Diffusion (MED)
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Pulse Therapeutics
Traumatic Brain Injury, Middle Cerebral Artery Stroke
Intracranial Pressure After Decompressive Craniectomy
Observational study to investigate the natural course of intracranial pressure (ICP) after decompressive craniectomy (DC) using long-term telemetric ICP monitoring.
- Conditions
- Traumatic Brain Injury, Middle Cerebral Artery Stroke, Intracranial Hemorrhages, Intracranial Hypertension
- Trial name
- NCT03364634
- Testing
- Intracranial pressure monitoring
- Volunteers
- 17 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stroke, Acute, Infarction, Middle Cerebral Artery
Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment.
The aim of the study is to determine the safety and efficacy on an autologous CD34+ subset bone marrow stem cell infusion into the middle cerebral artery in patients who have suffered acute middle cerebral artery stroke.
- Trial name
- NCT00761982
- Testing
- Infusion on autologous CD34+ stem cells into middle cerebral artery
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario Central de Asturias
Ischemic Stroke, Acute, Thrombolysis
Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion
The purpose of this study is to investigate the safety and efficacy of endovascular treatment with or without preceding intravenous Tenecteplase in patients with late-window (4.5-24 hours of symptom onset) acute ischemic stroke…
- Conditions
- Ischemic Stroke, Acute, Thrombolysis, Endovascular Treatment
- Trial name
- TNK-PLUS (NCT06221371)
- Testing
- Tenecteplase, direct EVT
- Where
- 21 sites in China
- Volunteers
- 391 people
- Sponsor
- Beijing Tiantan Hospital
Infarction, Middle Cerebral Artery
Thrombectomy Under Reopro Versus Alteplase to Treat Stoke
Intravenous (IV) Alteplase (rt-PA) is the gold standard for brain infarction within 4 h 30 of symptoms onset. Efficacy of this therapy is limited in the setting of large artery occlusions.
- Trial name
- TURANDOT (NCT02016547)
- Testing
- abciximab IV and thrombectomy, alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- SOS Attaque Cérébrale
Cerebral Herniation
Hemicraniectomy in Patients With Malign Middle Cerebral Artery Infarction
This trial is a prospective, randomized, controlled, clinical trial based on a stroke center. We randomly assigned 151 patients 41 years of age or older (median, 65 years; range, 41 to 83) with malignant middle cerebral artery…
- Trial name
- NCT04555460
- Testing
- Hemicraniectomy, Conservative medical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Ege University
Cerebrovascular Occlusion, Collateral Blood Circulation
The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion
Stroke is the first leading cause of death in China, and is responsible for almost 22.4% of deaths. In approximately 80% of cases stroke is ischaemic, i.e.
- Conditions
- Cerebrovascular Occlusion, Collateral Blood Circulation, Anterior Cerebral Circulation Infarction
- Trial name
- INCIMO (NCT02594995)
- Testing
- NBP
- Where
- China
- Volunteers
- 311 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Ischemic, Infarction, Middle Cerebral Artery
Testing of Identification Markers for Stroke
Stroke is the third leading cause of death and the first cause of physical disability and dementia worldwide. Ischemic stroke caused by large vessel occlusion (LVO) is responsible for the vast majority of deaths and disabilities.
- Conditions
- Stroke, Ischemic, Infarction, Middle Cerebral Artery, Infarction, Anterior Circulation, Brain
- Trial name
- TIME (NCT04292600)
- Testing
- POCKiT diagnostics' algorithm for LVO detection
- Where
- 3 sites in United States
- Volunteers
- 383 people
- Sponsor
- POCKiT diagnostics Ltd
Stroke, Middle Cerebral Artery Infarction
Gait Training for Persons With Stroke
The objective of this study is to investigate the effects of an automatic gait trainer (Lokomat) handled by physical therapists compared with categorized gait training by physical therapists in ambulatory stroke patients.
- Trial name
- GTS (NCT00612300)
- Testing
- Lokomat - Physical therapy, Physical therapy - Lokomat
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
Intracranial Embolism, Thrombosis
Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion
The purpose of the present, randomized, controlled multicenter phase III trial is to investigate the safety and efficacy of continuous 1-hour insonation of occluded middle cerebral artery with 2 MHz TCCS in stroke patients…
- Trial name
- NCT00336596
- Testing
- transcranial ultrasound in patients treated with iv t-PA
- Where
- 6 sites in Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Stroke, Acute, Infarction, Middle Cerebral Artery
Autologous Bone Marrow Stem Cells in Ischemic Stroke.
The aim of the study is to determine the safety and tolerability of an autologous CD34+ subset bone marrow stem cell infusion into the middle cerebral artery in patients who have suffered acute total or partial anterior…
- Trial name
- NCT00535197
- Testing
- Infusion of autologous CD34+ stem cells into middle cerebral artery
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Imperial College London
Infarction, Anterior Cerebral Artery, Infarction, Middle Cerebral Artery
An Observational Registry Study of LUOTAI in Patients With Acute Ischemic Stroke in Vietnam
Ischemic stroke occurs when an artery to the brain is blocked. If the artery remains blocked for more than a few minutes, the brain cells may die. This is why immediate medical treatment is critical.
- Conditions
- Infarction, Anterior Cerebral Artery, Infarction, Middle Cerebral Artery, Ischemic Attack, Transient
- Trial name
- NCT03679364
- Where
- 3 sites in Vietnam
- Volunteers
- 364 people
- Sponsor
- KPC Pharmaceuticals, Inc
Middle Cerebral Artery Stroke
Post-stroke Epilepsy: Primary Prophylaxis Study
Advance in stroke treatment have resulted in a dramatic reduction in the stroke mortality, however, the number of stroke survivors living with morbidity has increased significantly.
- Trial name
- NCT04858841
- Testing
- Levetiracetam Oral Product, Perampanel Oral Product
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- National Cheng Kung University